Neurobiological Correlates of Apathy in Alzheimer's Disease and Mild Cognitive Impairment: A Critical Review

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

The University and its libraries: reactions and resistance to scientific publishers

This paper addresses the relationship of copyright and the right of universities on scientific production. Information and Communication Technologies (ICTs) are causing many changes in the system of scientific communication, such as the creation of Institutional Repositories that aim to gather scientific production in digital format. The University needs quicker ways of spreading academic production and many questions are emerging due to contexts such as the Open Access movement. Thus, this paper questions the positioning of Universities, especially Public Universities, which despite having policies related to intellectual property to protect the transferring forms of research results to society; many times do not have a positioning or a mechanism that regulates the self-deposit of scientific production in these Institutional Repositories. In order to develop this paper, the following issues are addressed: lack of interest of the University in storing scientific production; reports on the relationship of the library with scientific publishing houses; the participation of faculty members and students in supporting the Free Access movement; and initiatives aimed at greater flexibility of copyright to the context of scientific production. In order to follow the development of these issues at international level, it was opted for qualitative research with non-participating direct observation to carry out the identification and description of copyright policy of important publishers from the ROMEO SHERPA site; therefore, it can be observed that there are changes regarding the publishers' flexibility before self-archiving of authors in open access institutional repositories in their universities. Given this scenario, we presente reflections and considerations that involve the progress and mainly the integration of the University and its faculty members; the institution should recommend and guide its faculty members not to transfer their copyrights, but to defend their right of copy to Institutional Repositories along with Publishing Houses.

Creative Commons: a convergence model between the ideal of commons and the possibilities of creation in contemporary times, opposed to copyright impediments

The contemporary individual finds on the Internet and especially on the Web facilitating conditions to build a basic infrastructure based on the concept of commons. He also finds favorable conditions which allow him to collaborate and share resources for the creation, use, reuse, access and dissemination of information. However, he also faces obstacles such as Copyright (Law 9610/98 in Brazil). An alternative is Creative Commons which not only allows the elaboration, use and dissemination of information under legal conditions but also function as a facilitator for the development of informational commons. This paper deals with this scenario.

Archives information publishing new design in post-custodial regime: the national archives experience digital vaults

The uses of Information and Communication Technologies (ICT) and Web environments for creation, treatment and availability of information have supported the emergence of new social-cultural patterns represented by convergences in textual, image and audio languages. This paper describes and analyzes the National Archives Experience Digital Vaults as a digital publishing web environment and as a cultural heritage. It is a complex system - synthesizer of information design options at information setting, provides new aesthetic aspects, but specially enlarges the cognition of the subjects who interact with the environment. It also enlarges the institutional spaces that guard the collective memory beyond its role of keeping the physical patrimony collected there. Digital Vaults lies as a mix of guide and interactive catalogue to be dealt in a ludic way. The publishing design of the information held on the Archives is meant to facilitate access to knowledge. The documents are organized in a dynamic and not chronological way. They are not divided in fonds or distinct categories, but in controlled interaction of documents previously indexed and linked by the software. The software creates information design and view of documental content that can be considered a new paradigm in Information Science and are part of post-custodial regime, independent from physical spaces and institutions. Information professionals must be prepared to understand and work with the paradigmatic changes described and represented by the new hybrid digital environments; hence the importance of this paper. Cyberspace interactivity between user and the content provided by the environment design provide cooperation, collaboration and sharing knowledge actions, all features of networks, transforming culture globally.

Reliability of one-repetition maximum test in untrained young adult men and women

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Hip muscles strength and activation in older fallers and non-fallers

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Moderate intensity and volume downhill run does not impair knee joint stability at early and late phases of quadriceps/hamstrings contraction

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

PSEN1 and PSEN2 Gene Expression in Alzheimer's Disease Brain: A New Approach

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Physical Exercise Improves Peripheral BDNF Levels and Cognitive Functions in Mild Cognitive Impairment Elderly with Different BDNF Val66Met Genotypes

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Obstacle Crossing with Dual Tasking is a Danger for Individuals with Alzheimer's Disease and for Healthy Older People

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Greening the work force in Brazilian hotels: The role of environmental training

BACKGROUND: Organizations are increasingly required to reduce their environmental impact through the adoption of environmental management, which requires the support of human resource practices.OBJECTIVE: The objective of this study is to determine whether human resource management practices, especially training, are supporting environmental management practices at four hotels located in Brazil.METHODS: This research is qualitative, based on the analysis of four hotels in Brazil.RESULTS: Based on the systematized empirical evidence collected from four hotels (Hotels A, B, C, and D), it can be concluded that: (1) human resource management is still not fully aligned with environmental objectives at the hotels studied; (2) only Hotel B has implemented environmental management practices and aligned with human resource management in a more developed manner, which may indicate that these two variables of analysis could have interrelations; (3) environmental training as a human resource management practice was verified in all hotels analyzed.CONCLUSIONS: The greening of human resources practices is not fully aligned with environmental objectives in the hotels studied. If these hotels really wish to "go green," environmental training will be necessary. Hotel stakeholders play a major role in implementing the greening of the hotel industry.

Amazônia em xeque

Com o intuito de promover uma ação internacional para a gestão sustentável, conservação e desenvolvimento das florestas e chamar a atenção da população para o papel destas na geração de benefícios econômicos, sociais e ambientais, principalmente para os povos que dependem delas para sobreviver, a Assembléia Geral da Organização das Nações Unidas (ONU), declarou 2011 como o Ano Internacional das Florestas. Paradoxal a esta ação, o ano de 2011 é também marcado pela inauguração da Rodovia Interoceânica Sul (IOS) no Peru, que ao conectar-se a malha rodoviária brasileira cria um elo de ligação direta entre o Oceano Atlântico e o Oceano Pacífico. Segundo seus idealizadores, o projeto aumentará as possibilidades de comércio internacional. Além de incrementar o comércio bilateral e integrar a Macro-Região Sul do Peru ao restante do país, a IOS proporciona ao Brasil uma alternativa de acesso ao Oceano Pacífico e aos mercados da Ásia e, ao Peru, um acesso mais eficiente ao Atlântico e aos mercados da costa leste dos EUA e da Europa. Por outro lado, a IOS passa por uma das mais preservadas regiões da Amazônia e, é considerada de importância única em termos de risco para os esforços mundiais de conservação da biodiversidade e de respeito aos direitos das últimas populações humanas que ali vivem sem ou com muito pouco contato com a sociedade moderna. Os impactos socioambientais ligados à construção e/ou reabilitação de estradas em territórios tropicais úmidos adquiriram fama mundial precisamente com a BR- 364, trecho principal desse corredor no território brasileiro. A pavimentação desta estrada nos anos 1980 provocou desastres ambiental e social gravíssimos no norte de Mato Grosso, em Rondônia e no Acre. Desta forma, a presente pesquisa tem por objetivo fazer um estudo... (Resumo completo, clicar acesso eletrônico abaixo)

Desempenho em tarefas computacionais em função do uso de diferentes periféricos

With the popularization of information technology and government incentives for inclusion in the digital era, an important issue for science and for industry is the design of tool s for entrance of input to the device, that is , the peripherals at tached to the computer that are reaching the consumer. In order to minimize the impact of repetitive use of these tools for entry, whether when playing games or working, more studies are in need to developper ipherals that enable comfort and effi ciency. This study examined the per formance of individuals with differents izes of hand (i.e., large and small ) in performance of three task s on the computer us ing mouses of small and large sizes. For thi s study, 19 young adul ts were volunteers and asked to per form activities with greater precision and speed. In addition, al l participants were asked on the use of computers. The results showed no statistically significant differences in the performance related to the size of the mouse between subjects with small and large hands. However, an interest ingresult as observed with respect to the performance of individuals with a large hand to perform tas ks more quickly. The results of this study suggest that with both, the small and the large mouse, individuals with big hands have a fas terper formancein tasks of dragging and clicking when compared with the performance of indi viduals with small hand.

Human ABCB1 confers cells resistance to cytotoxic guanidine alkaloids from Pterogyne nitens

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Ditregra - An auxiliary program for structural determination of diterpenes

This work describes the creation of heuristics rules based on 13C-NMR spectroscopy that characterize several skeletal types of diterpenes. Using a collection of 2745 spectra we built a database linked to the expert system SISTEMAT. Several programs were applied to the database in order to discover characteristic signals that identify with a good performance, a large diversity of skeletal types. The heuristic approach used was able to differentiate groups of skeletons based firstly on the number of primary, secondary, tertiary and quaternary carbons, and secondly the program searches, for each group, if there are ranges of chemical shifts that identifies specific skeletal type. The program was checked with 100 new structures recently published and was able to identify the correct skeleton in 65 of the studied cases. When the skeleton has several hundreds of compounds, for example, the labdanes, the program employs the concept of subskeletal, and does not classify in the same group labdanes with double bounds at different positions. The chemical shift ranges for each subskeletal types and the structures of all skeletal types are given. The consultation program can be obtained from the authors. © 1997 - IOS Press. All rights reserved.