Modeling of allergen proteins found in sea food products

Shellfish are a source of food allergens, and their consumption is the cause of severe allergic reactions in humans. Tropomyosins, a family of muscle proteins, have been identified as the major allergens in shellfish and mollusks species. Nevertheless, few experimentally determined three-dimensional structures are available in the Protein Data Base (PDB). In this study, 3D models of several homologous of tropomyosins present in marine shellfish and mollusk species (Chaf 1, Met e1, Hom a1, Per v1, and Pen a1) were constructed, validated, and their immunoglobulin E binding epitopes were identified using bioinformatics tools. All protein models for these allergens consisted of long alpha-helices. Chaf 1, Met e1, and Hom a1 had six conserved regions with sequence similarities to known epitopes, whereas Per v1 and Pen a1 contained only one. Lipophilic potentials of identified epitopes revealed a high propensity of hydrophobic amino acids in the immunoglobulin E binding site. This information could be useful to design tropomyosin-specific immunotherapy for sea food allergies.

Determination of some quality properties of marinated sea bream (Sparus Aurata L., 1758) during cold storage

In this study, it was aimed to determine the effect of sea bream (Sparus aurata) marinated some quality properties during cold storage. The fillets of fish were immersed into brine including 3.5% acetic acid 11% salt in the ratio of 1: 1.5 (fish: marinate brine) for marination process. After the process of ripening, samples were grouped into two and packed in plastic containers; one being plain (in sunflower oil) and the other being sauced (sauced prepared with sunflower oil). During storage, sensory, crude protein, lipid, dry matter and crude ash, TBA, TVB-N, TMA-N and peroxide analyses were done periodically. According to results of 200 days of storage, TVB-N values of sea bream marinates packaged as plain and sauced were 15.86/14.89 mg/100g, TBA 7.06/7.99 mg MA/kg, TMA-N 2.97/3.12, mg/100g, the value of peroxide was 7.23/7.45 meq/kg respectively. According to chemical and sensory analyses results obtained in the study; it was concluded that sea bream marinates packaged as plain and sauced can be stored in +4 °C for 200 days.

Air-Sea Battle -konsepti John Wardenin Enemy as a System -teorian näkökulmasta

Tutkielman tavoitteena oli analysoida Air-Sea Battle -konseptia ja sen lähtökohtana ollutta viholliskuvaa John Wardenin Enemy as a System -teorian näkökulmasta julkisten asiakirjojen, raporttien ja artikkeleiden avulla. Tutkimusmenetelmänä on käytetty teoriaohjaavaa sisällönanalyysia. Tutkimusongelmaksi muodostui: ”Miten Air-Sea Battle -konsepti näyttäytyy Wardenin Enemy as a System -teorian näkökulmasta?” Tutkimuskysymyksien avulla pyrittiin lisäksi löytämään konseptin kehittämiseen johtaneita tekijöitä suurstrategisella tasolla, arvioimaan konseptin mukaista aseellisen voiman käyttöä sekä analysoimaan konseptia suhteessa Wardenin näkemyksiin sotilasstrategiasta. Wardenin Enemy as a System -teoria on esitelty tutkielman alkupuolella hyödyntäen alkuperäistekstejä, aiheesta kirjoitettuja tutkimuksia ja artikkeleita sekä sotataidollista kirjallisuutta. Air-Sea Battle -konseptia käsittelevän luvun aineisto on luokiteltu Wardenin neljän strategisen kysymyksen teemojen, eli tavoitteen, vaikuttamisen kohteiden, keinojen ja irtautumisen, mukaisesti. Tärkeimmät lähteet varsinaisen Air-Sea Battle -asiakirjan lisäksi olivat Yhdysvaltojen turvallisuus- ja sotilasstrategiaa määrittelevät dokumentit, tutkimuslaitosten julkaisemat raportit sekä aikakauslehtiartikkelit. Aineiston perusteella Yhdysvallat näkee tiettyjen valtioiden, kuten Kiinan, kehittyvät niin kutsutut anti-access/area denial -suorituskyvyt uhkana alueelliselle tasapainolle ja heidän kyvylleen ylläpitää sotilaallista läsnäoloa strategisesti merkittävillä alueilla. Air-Sea le -konseptin tavoitteena on määritellä ja kehittää suorituskyvyt, operatiiviset suunnitelmat ja toimintamallit, joiden mukaan toimivalla joukolla kyetään luomaan riittävä pelotevaikutus konfliktin ehkäisemiseksi tai säilyttämään toiminnanvapaus alueella sen muodostuessa.

The Baltic : sea of changes

Finnish Defence Studies is published under the auspices of the National Defence College, and the contributions reflect the fields of research and teaching of the College. Finnish Defence Studies will occasionally feature documentation on Finnish Security Policy. Views expressed are those of the authors and do not necessarily imply endorsement by the National Defence College.

EU Strategy for the Baltic Sea Region: its added value in environmental social and economic dimensions

The European Council has invited the European Commission to present the first macro-regional strategy – the EU Strategy for the Baltic Sea Region (EUSBSR) on the 14th of December 2007, primarily to address collective challenges and opportunities of the Region and also to engender cohesion in support of an European integration policy. However, macro-regional strategies conceived to aid European integration and territorial cohesion were viewed by academics with skepticism, obscuring the strategies’ potential impact. This thesis intends to investigate and measure the added value of the EUSBSR in order to analyze its impact on regional development and its feasibility as a guide for future programs intending to strengthen European cohesion and integration. To determine the added value of the EUSBSR the thesis is organized into three sections, so as to address environmental, social, and economic concerns, respectively. The first case examines EU-Russia cooperation in an environmental context to investigate how environmental cooperation with an external neighbor could forge increased cohesion in a macro-regional setting. To figure the added cooperation that academic cooperation among universities would contribute to social dimension, the work has chosen several study results. Lastly, to measure out the added value for the economic strategy objective, the study employs the project for Improved Global Competitiveness in an example of ‘A Baltic Sea Region Program for Innovation, Cluster and SME-Networks’ as an economic plan.

Between Dugin’s Eurasianism and Mahan’s Sea Power Concept: Russia’s Geopolitical Discourse within Foucault’s ‘Discursive Tree’ before and After the Incorporation of the Crimea

The fall of 2013 could be characterized as a crossroad in the geopolitics of Eastern Europe, namely Ukraine. Two rivalry geopolitical projects have been developing throughout the post-Cold War years, and it seems that they reached a collision point in Ukraine; a country whose authorities have been for long switching sides between the European Union and the Russian Federation in their foreign policy commitments. The refusal/postponing to sign the Association Agreement with Brussels, an expected event by a large category of the Ukrainian society, by Yanukovich’s government led to the outset of the latter; and brought a pro-Western, anti-Russian government in Kyiv. It seems that Ukraine, after those events, has embarked definitively on the path of integration into the West (European Union and possibly NATO). The Russian Federation, who has been throughout Putin’s years engaged into the re-integration of post-Soviet space, reacted to these developments in an assertive manner by violating borders, agreements and the territorial integrity of Ukraine. Thus, the incorporation of the Crimea into the Russian Federation is the first in its kind in the post-Soviet space, despite the existence of various other conflicts that broke out in the region after the Soviet Union broke up. I will investigate in this thesis the nature of what will be labelled, in this work, the Crimean issue. I argue that the incorporation of the Crimean peninsula into the Russian Federation marks a new era in Russian geopolitical thinking that shapes, to a far extent, Russian foreign policy. Discourse analysis will be the methodological basis for this study, with a special focus on Michel Foucault’s Archaeology of Knowledge. The innovation that this research brings is the fact that it discusses Russian geopolitical discourse within the scope of Foucault’s ‘discursive tree’, with a reference to the Crimean issue. A wide range of primary sources will be consulted in this study such as presidential addresses to the Federal Assembly (2000-2014), Foreign Policy Concepts of the Russian Federation (2000, 2008), Russian maritime doctrines, as wells as Dugin’s Osnovy Geopolitiki (Foundations of Geopolitics), Mahan’s (The Influence of Sea Power Upon History, 1660–1783) and other Eurasianism related literature.

Stories from the City, Stories from the Sea - How place brands are perceived differently from the points of view of a local and a tourist

Tämä tutkielma käsittelee paikkamarkkinointia ja paikkabrändäystä. Tutkielmassa tarkastellaan paikallisen ja turistin tapoja muodostaa kaupunkibrändi; mistä palasista brändi muodostuu kirjallisuuden ja haastateltavien mukaan, koetaanko eri palaset vaihtelevissa määrin tärkeiksi riippuen siitä, tarkastellaanko paikkaa paikallisena vai turistina, ja löytyykö jotain yhteisiä retorisia nimittäjiä sille, miten kotikaupungista puhutaan verrattuna lomakaupunkiin. Tutkimuksessa haastateltiin yli kolmeakymmentä henkilöä heidän kotikaupungeistaan ja kaupungeista, joihin he olivat matkustaneet lomalle. Haastateltavat olivat suurinpiirtein samanikäisiä, mutta eri kaupungeista ja matkustaneet eri paikkoihin. Haastateltavia pyydettiin ensin kuvailemaan vapaasti kotikaupunkiaan ja sen jälkeen kaupungista kysyttiin kirjallisuuteen perustuen kysymyksiä. Sama menetelmä toistettiin lomakohteen suhteen. Tutkimuksesta selvisi, että paikkabrändi muodostetaan samoista komponenteista, mutta joidenkin komponenttien merkitys on tärkeämpi kotikaupungissa, kun taas toiset komponentit ovat tärkeitä lomakohteen suhteen. Ihmiset ja kulttuuri yleisesti koettiin tärkeinä komponentteina molemmista paikkabrändeistä puhuttaessa, kun taas kotikaupungin brändinmuodostukseen kuului vahvemmin lait ja muut käytännölliset menettelytavat kuten liikenteen toimivuus. Lomakohteen brändinmuodostuksessa vapaudella tehdä mitä haluaa oli suuri merkitys ja vapautta nähtiin eri muodoissa. Retoriikka kotikaupungista puhuttaessa oli selvästi negatiivista, kun taas lomakohteesta puhuttiin yleisesti ottaen positiiviseen sävyyn. Suhde kotikaupunkiin oli ambivalentti, sillä huonojakin puolia mainittaessa niitä puolusteltiin, tai kotikaupungista mainittiin loppujen lopuksi jotain hyvää. Tutkimusten tuloksiin perustuen toimenpidesuosituksina ehdotetaan olemassaolevan autenttisen kulttuurin ylläpitämäistä, korostamista ja kaupungin orgaanista kehittämistä suuntaan, jossa se on hyvä paikka niin elämiseen kuin lomailuun. Identiteetti, imago ja ihmiset kietoutuvat tiiviisti yhteen, minkä vuoksi kaupunkisuunnittelun- ja kehittämisen tehtävänä on pitää huolta, että kaupunki on onnistunut molempien ryhmien suhteen, ja molemmat ryhmät levittävät kaupungista positiivista sanomaa.

Geographical Studies of Underwater Light Dynamics in the Coastal Archipelago of SW Finland, Baltic Sea

The underwater light field is an important environmental variable as it, among other things, enables aquatic primary production. Although the portion of solar radiation that is referred to as visible light penetrates water, it is restricted to a limited surface water layer because of efficient absorption and scattering processes. Based on the varying content of optical constituents in the water, the efficiency of light attenuation changes in many dimensions and over various spatial and temporal scales. This thesis discusses the underwater light dynamics of a transitional coastal archipelago in south-western Finland, in the Baltic Sea. While the area has long been known to have a highly variable underwater light field, quantified knowledge on the phenomenon has been scarce, patchy, or non-existent. This thesis focuses on the variability in the underwater light field through euphotic depths (1% irradiance remaining), which were derived from in situ measurements of vertical profiles of photosynthetically active radiation (PAR). Spot samples were conducted in the archipelago of south-western Finland, mainly during the ice-free growing seasons of 2010 and 2011. In addition to quantifying both the seasonal and geographical patterns of euphotic depth development, the need and usability of underwater light information are also discussed. Light availability was found to fluctuate in multiple dimensions and scales. The euphotic depth was shown to have combined spatio-temporal dynamics rather than separate changes in spatial and temporal dimensions. Such complexity in the underwater light field creates challenges in data collection, as well as in its utilisation. Although local information is needed, in highly variable conditions spot sampled information may only poorly represent its surroundings. Moreover, either temporally or spatially limited sampling may cause biases in understanding underwater light dynamics. Consequently, the application of light availability data, for example in ecological modelling, should be made with great caution.

The outtermost or the fartheste parte of the Easterne Sea eastwardly, the which lyeth inclosed with in the coastes of East Finland, Rusland, & Lyffland, and wherein lye the Narve and Wyburgh the twoo furthermost places or marchante townes of the whole Easterne Navigation, with all the circumstances of the situation, the isles and Swedish rockes called Schares

Janamittakaavat: Englishe leagues 20 in a degree ; Spanische leagues 17 1/2 in a degree ; Dutche leagues 15 in a degree.

Resolución No. 080. ¿Cual es el control de legalidad que ejercen las Cámaras de comercio frente a las reformas estatutarias? ¿Cuáles son los elementos para que sea procedente la revocatoria directa del acto administrativo de inscripción?

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Resolución N° 240 ¿Cuáles son los presupuestos necesarios para que sea procedente la inscripción de una medida cautelar sobre un establecimiento de comercio?

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Preguntas frecuentes. Haz que la innovación sea parte de las estrategias

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