[32 phot. de types et de costumes de Serbie, par Jean Lacroix, phot. à Genève, B. Danilovic, F. Regetzky, D. Krstovic, Georg Kraljevacki, M.M. Handzserlija, N. Lekitsch, tous phot. à Belgrade, F. Luckhardt, phot. à Vienne, don Vladimir Yakchitch en 1885]

Donateur : Yakchitch, Vladimir (18..-19..? ; Statisticien)

Hermenêutica e saúde: reflexões sobre o pensamento de Hans-Georg Gadamer

Este artigo tem como objetivo contribuir para a utilização da hermenêutica de Gadamer na prática de enfermagem. Reflete acerca da incorporação do paradigma conceitual sobre a saúde, o cuidado e o diálogo terapêutico. Na primeira parte, apresenta a discussão dos conceitos Gadamerianos da obra Verdade e Método, a filosofia hermenêutica proposta pelo filósofo e finaliza com a articulação do conceito de saúde apresentado na obra O Caráter Oculto da Saúde, que propõe o cuidado mediado pelo diálogo terapêutico e sua utilização pelos profissionais de enfermagem.

Loi sur les finances du 28 avril 1816

[Acte royal. 1816-04-00]

Statuts, ordonnances et règlemens de la communauté des maîtres rôtisseurs de la ville, fauxbourgs et banlieue de Paris. Du mois de juin 1744. Rédigés par M. l'abbé Mxxx [J.-B. Le Mascrier]...

[Acte. 1744-06-00]

Local transient myocardial liposomal gene transfer of inducible nitric oxide synthase does not aggravate myocardial function and fibrosis and leads to moderate neovascularization in chronic myocardial ischemia in pigs.

Microcirculation (2010) 17, 69-78. doi: 10.1111/j.1549-8719.2010.00002.x Abstract Background: This study was designed to explore the effect of transient inducible nitric oxide synthase (iNOS) overexpression via cationic liposome-mediated gene transfer on cardiac function, fibrosis, and microvascular perfusion in a porcine model of chronic ischemia. Methods and Results: Chronic myocardial ischemia was induced using a minimally invasive model in 23 landrace pigs. Upon demonstration of heart failure, 10 animals were treated with liposome-mediated iNOS-gene-transfer by local intramyocardial injection and 13 animals received a sham procedure to serve as control. The efficacy of this iNOS-gene-transfer was demonstrated for up to 7 days by reverse transcriptase-polymerase chain reaction in preliminary studies. Four weeks after iNOS transfer, magnetic resonance imaging showed no effect of iNOS overexpression on cardiac contractility at rest and during dobutamine stress (resting ejection fraction: control 27%, iNOS 26%; P = ns). Late enhancement, infarct size, and the amount of fibrosis were similar between groups. Although perfusion and perfusion reserve in response to adenosine and dobutamine were not significantly modified by iNOS-transfer, both vessel number and diameter were significantly increased in the ischemic area in the iNOS-treated group versus control (point score: control 15.3, iNOS 34.7; P < 0.05). Conclusions: Our findings demonstrate that transient iNOS overexpression does not aggravate cardiac dysfunction or postischemic fibrosis, while potentially contributing to neovascularization in the chronically ischemic heart.