Integração dos imigrantes da República Democrática do Congo no Bairro Camama 1 em Luanda

Com o presente trabalho de investigação procurámos perceber os desafios ao nível social e económico que os imigrantes da República Democrática do Congo têm experimentado no seu processo de integração no Bairro Camama1, na cidade de Luanda, a forma como a sociedade angolana e o Estado Angolano lidam com a situação bem como as medidas tomadas para lidar com este fenómeno social crescente. O trabalho de campo foi realizado no bairro Camama 1 com a aplicação de um inquérito que combina questões abertas e fechadas e participaram no estudo 69 imigrantes da República Democrática do Congo. Os resultados da investigação levaram-nos a concluir que a integração dos imigrantes da RDC se faz essencialmente ao nível do sector económico ou seja, é sobretudo uma integração de carácter económico e não social. Apesar da interação com os angolanos e de estarem inseridos no mercado de emprego secundário, os imigrantes da RDC não estão registados como residentes do bairro e apresentam um estatuto jurídico precário o que lhes impossibilita a integração social: são invisíveis para a sociedade angolana.

Ação de anestésicos gerais em canais iônicos

Dissertação (mestrado)—Universidade de Brasília, Instituto de Ciências Biológicas, Departamento de Biologia Molecular, 2016.

Induction of Microalgal Lipids for Biodiesel Production in Tandem with Sequestration of High Carbon Dioxide Concentration

There is no doubt that sufficient energy supply is indispensable for the fulfillment of our fossil fuel crises in a stainable fashion. There have been many attempts in deriving biodiesel fuel from different bioenergy crops including corn, canola, soybean, palm, sugar cane and vegetable oil. However, there are some significant challenges, including depleting feedstock supplies, land use change impacts and food use competition, which lead to high prices and inability to completely displace fossil fuel [1-2]. In recent years, use of microalgae as an alternative biodiesel feedstock has gained renewed interest as these fuels are becoming increasingly economically viable, renewable, and carbon-neutral energy sources. One reason for this renewed interest derives from its promising growth giving it the ability to meet global transport fuel demand constraints with fewer energy supplies without compromising the global food supply. In this study, Chlorella protothecoides microalgae were cultivated under different conditions to produce high-yield biomass with high lipid content which would be converted into biodiesel fuel in tandem with the mitigation of high carbon dioxide concentration. The effects of CO2 using atmospheric and 15% CO2 concentration and light intensity of 35 and 140 µmol m-2s-1 on the microalgae growth and lipid induction were studied. The approach used was to culture microalgal Chlorella protothecoides with inoculation of 1×105 cells/ml in a 250-ml Erlenmeyer flask, irradiated with cool white fluorescent light at ambient temperature. Using these conditions we were able to determine the most suitable operating conditions for cultivating the green microalgae to produce high biomass and lipids. Nile red dye was used as a hydrophobic fluorescent probe to detect the induced intracellular lipids. Also, gas chromatograph mass spectroscopy was used to determine the CO2 concentrations in each culture flask using the closed continuous loop system. The goal was to study how the 15% CO2 concentration was being used up by the microalgae during cultivation. The results show that the condition of high light intensity of 140 µmol m-2s-1 with 15% CO2 concentration obtain high cell concentration of 7 x 105 cells mL-1 after culturing Chlorella protothecoides for 9 to 10 day in both open and closed systems respectively. Higher lipid content was estimated as indicated by fluorescence intensity with 1.3 to 2.5 times CO2 reduction emitted by power plants. The particle size of Chlorella protothecoides increased as well due to induction of lipid accumulation by the cells when culture under these condition (140 µmol m-2s-1 with 15% CO2 concentration).

Involvement of cell surface TG2 in the aggregation of K562 cells triggered by gluten

Gluten-induced aggregation of K562 cells represents an in vitro model reproducing the early steps occurring in the small bowel of celiac patients exposed to gliadin. Despite the clear involvement of TG2 in the activation of the antigen-presenting cells, it is not yet clear in which compartment it occurs. Herein we study the calcium-dependent aggregation of these cells, using either cell-permeable or cell-impermeable TG2 inhibitors. Gluten induces efficient aggregation when calcium is absent in the extracellular environment, while TG2 inhibitors do not restore the full aggregating potential of gluten in the presence of calcium. These findings suggest that TG2 activity is not essential in the cellular aggregation mechanism. We demonstrate that gluten contacts the cells and provokes their aggregation through a mechanism involving the A-gliadin peptide 31-43. This peptide also activates the cell surface associated extracellular TG2 in the absence of calcium. Using a bioinformatics approach, we identify the possible docking sites of this peptide on the open and closed TG2 structures. Peptide docks with the closed TG2 structure near to the GTP/GDP site, by establishing molecular interactions with the same amino acids involved in stabilization of GTP binding. We suggest that it may occur through the displacement of GTP, switching the TG2 structure from the closed to the active open conformation. Furthermore, docking analysis shows peptide binding with the β-sandwich domain of the closed TG2 structure, suggesting that this region could be responsible for the different aggregating effects of gluten shown in the presence or absence of calcium. We deduce from these data a possible mechanism of action by which gluten makes contact with the cell surface, which could have possible implications in the celiac disease onset.

Avaliação da estabilidade postural durante a realização de exercícios de equilíbrio com diferentes níveis de dificuldade

Projeto de Graduação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Licenciado em Fisioterapia

Iowa Medical Malpractice Annual Report, 2014

The Iowa Insurance Division requested open and closed claim data for calendar year 2014 from licensed insurance companies pursuant to Iowa Code Section 505.27. Licensed companies who wrote medical malpractice insurance in Iowa during the period from January 1, 2014, through December 31, 2014, were asked to provide specific data for claims closed during that period and separately those remaining open at the end of the year.

Iowa Medical Malpractice Annual Report, 2006

The Iowa Insurance Division requested open and closed claim data for a calendar year from licensed insurance companies pursuant to Iowa Code Section 505.27. Licensed companies who wrote medical malpractice insurance in Iowa during the period from January 1, through December 31, were asked to provide specific data for claims closed during that period and separately those remaining open at the end of the year.

Iowa Medical Malpractice Annual Report, 2007

The Iowa Insurance Division requested open and closed claim data for a calendar year from licensed insurance companies pursuant to Iowa Code Section 505.27. Licensed companies who wrote medical malpractice insurance in Iowa during the period from January 1, through December 31, were asked to provide specific data for claims closed during that period and separately those remaining open at the end of the year.

Iowa Medical Malpractice Annual Report, 2008

The Iowa Insurance Division requested open and closed claim data for a calendar year from licensed insurance companies pursuant to Iowa Code Section 505.27. Licensed companies who wrote medical malpractice insurance in Iowa during the period from January 1, through December 31, were asked to provide specific data for claims closed during that period and separately those remaining open at the end of the year.

Iowa Medical Malpractice Annual Report, 2009

The Iowa Insurance Division requested open and closed claim data for a calendar year from licensed insurance companies pursuant to Iowa Code Section 505.27. Licensed companies who wrote medical malpractice insurance in Iowa during the period from January 1, through December 31, were asked to provide specific data for claims closed during that period and separately those remaining open at the end of the year.

Iowa Medical Malpractice Annual Report, 2009 Revised

The Iowa Insurance Division requested open and closed claim data for a calendar year from licensed insurance companies pursuant to Iowa Code Section 505.27. Licensed companies who wrote medical malpractice insurance in Iowa during the period from January 1, through December 31, were asked to provide specific data for claims closed during that period and separately those remaining open at the end of the year.

Iowa Medical Malpractice Annual Report, 2010

The Iowa Insurance Division requested open and closed claim data for a calendar year from licensed insurance companies pursuant to Iowa Code Section 505.27. Licensed companies who wrote medical malpractice insurance in Iowa during the period from January 1, through December 31, were asked to provide specific data for claims closed during that period and separately those remaining open at the end of the year.

Iowa Medical Malpractice Annual Report, 2011

The Iowa Insurance Division requested open and closed claim data for a calendar year from licensed insurance companies pursuant to Iowa Code Section 505.27. Licensed companies who wrote medical malpractice insurance in Iowa during the period from January 1, through December 31, were asked to provide specific data for claims closed during that period and separately those remaining open at the end of the year.

Iowa Medical Malpractice Annual Report, 2012

The Iowa Insurance Division requested open and closed claim data for a calendar year from licensed insurance companies pursuant to Iowa Code Section 505.27. Licensed companies who wrote medical malpractice insurance in Iowa during the period from January 1, through December 31, were asked to provide specific data for claims closed during that period and separately those remaining open at the end of the year.

Iowa Medical Malpractice Annual Report, 2013

The Iowa Insurance Division requested open and closed claim data for a calendar year from licensed insurance companies pursuant to Iowa Code Section 505.27. Licensed companies who wrote medical malpractice insurance in Iowa during the period from January 1, through December 31, were asked to provide specific data for claims closed during that period and separately those remaining open at the end of the year.