Armeliaisuuslaitoksesta kuriositeetiksi : Kivennavan Lintulan nunnaluostarin miljöön muotoutuminen 1800-luvun lopulta 1930-luvulle

Zusammenfassung: Von einer Wohltätigkeitseinrichtung zur Kuriosität : wie sich das Milieu des Nonnenklosters Lintula in Kivinebb in der Zeit vom Ende des 19. Jahrhunderts bis in die 1930er Jahre wandelte

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.

Obesity is globally prevalent and highly heritable, but its underlying genetic factors remain largely elusive. To identify genetic loci for obesity susceptibility, we examined associations between body mass index and ∼ 2.8 million SNPs in up to 123,865 individuals with targeted follow up of 42 SNPs in up to 125,931 additional individuals. We confirmed 14 known obesity susceptibility loci and identified 18 new loci associated with body mass index (P < 5 × 10⁻⁸), one of which includes a copy number variant near GPRC5B. Some loci (at MC4R, POMC, SH2B1 and BDNF) map near key hypothalamic regulators of energy balance, and one of these loci is near GIPR, an incretin receptor. Furthermore, genes in other newly associated loci may provide new insights into human body weight regulation.

Vanhustyöntekijät - näkemyksiä vanhustyöstä ja sen kehittämisestä

Summary: The professional caregivers of the elderly in Satakunta

Koherenssi-käsitys ja epäkypsät defenssit

Summary: Sense of coherence and immature defenses