Scientific value of systematic reviews: survey of editors of core clinical journals.

BACKGROUND: Synthesizing research evidence using systematic and rigorous methods has become a key feature of evidence-based medicine and knowledge translation. Systematic reviews (SRs) may or may not include a meta-analysis depending on the suitability of available data. They are often being criticised as 'secondary research' and denied the status of original research. Scientific journals play an important role in the publication process. How they appraise a given type of research influences the status of that research in the scientific community. We investigated the attitudes of editors of core clinical journals towards SRs and their value for publication.¦METHODS: We identified the 118 journals labelled as "core clinical journals" by the National Library of Medicine, USA in April 2009. The journals' editors were surveyed by email in 2009 and asked whether they considered SRs as original research projects; whether they published SRs; and for which section of the journal they would consider a SR manuscript.¦RESULTS: The editors of 65 journals (55%) responded. Most respondents considered SRs to be original research (71%) and almost all journals (93%) published SRs. Several editors regarded the use of Cochrane methodology or a meta-analysis as quality criteria; for some respondents these criteria were premises for the consideration of SRs as original research. Journals placed SRs in various sections such as "Review" or "Feature article". Characterization of non-responding journals showed that about two thirds do publish systematic reviews.¦DISCUSSION: Currently, the editors of most core clinical journals consider SRs original research. Our findings are limited by a non-responder rate of 45%. Individual comments suggest that this is a grey area and attitudes differ widely. A debate about the definition of 'original research' in the context of SRs is warranted.

Pentateuque, Hexateuque et historiographie deutéronomiste. Le problème du début et de la fin du livre de Josué

The book of Joshua is in the very center of the recent discussion about the existence of a coherent deuteronomistic redaction in Deut to 2 Kings during the exilic period. This article analyses the beginning (Josh 1.1-9) and the end (Josh 23 and 24) of Josh. Josh 1.1-2,5-7 and chapter 23 belong to the dtr edition. Josh 23 was followed by Judg 2.6ff. During the Persian period, Deuteronomists and priests intended to publish one Law for the whole community. There was probably a discussion whether the Torah should be a Penta- or a Hexateuch. This discussion may explain such a text as Josh 24 which clearly tries to construct an Hexateuch (cf. also Gen. 50.25: Exod 13.19; Josh 24.32). But since the Torah is about foundations, the main theological trends agreed to have its end with the death of Moses.

Some information concerning the State Historical Society of Iowa,1910.

In recent years historical research seems to be the State Historical Society's main function, although it was formed with the principal functions of collection, preservation and exhibition. Now, instead of simply attempting to make the largest possible collection of historical materials in one place, this society will now endeavor to compile, publish and distribute accurate and scientific historical literature. The book also lists publications, information on the library and on membership.

Compendium of projects in the European nanosafety cluster

This is the second edition of the compendium. Since the first edition a number of important initiatives have been launched in the shape of large projects targeting integration of research infrastructure and new technology for toxicity studies and exposure monitoring.The demand for research in the area of human health and environmental safety management of nanotechnologies is present since a decade and identified by several landmark reports and studies. Several guidance documents have been published. It is not the intention of this compendium to report on these as they are widely available.It is also not the intention to publish scientific papers and research results as this task is covered by scientific conferences and the peer reviewed press.The intention of the compendium is to bring together researchers, create synergy in their work, and establish links and communication between them mainly during the actual research phase before publication of results. Towards this purpose we find useful to give emphasis to communication of projects strategic aims, extensive coverage of specific work objectives and of methods used in research, strengthening human capacities and laboratories infrastructure, supporting collaboration for common goals and joint elaboration of future plans, without compromising scientific publication potential or IP Rights.These targets are far from being achieved with the publication in its present shape. We shall continue working, though, and hope with the assistance of the research community to make significant progress. The publication will take the shape of a dynamic, frequently updated, web-based document available free of charge to all interested parties. Researchers in this domain are invited to join the effort, communicating the work being done. [Auteurs]

Iowa Ag Insider, August 31, 2012

Welcome to the initial edition of the Iowa Ag Insider, the newsletter of the Iowa Department of Agriculture and Land Stewardship. We see this newsletter as a way to keep people informed of the activities of the Department and also highlight some of the exciting things going on in Iowa agriculture in general. If you know of events or stories that should be included in future newsletters I hope that you will share them with us so they can be included in future editions. Also, if you know of people who would enjoy receiving this newsletter I hope you will pass it on as the information on how to subscribe is on the bottom of each issue. This is an exciting time of year in Iowa as farmers and everyone involved in agriculture gets ready to kickoff the growing season. We wish everyone a successful and safe 2013 as we get to the business of growing the crops that help power Iowa’s economy and feed the people of our state and trading partners around the world. Iowa is fortunate to have such a dynamic agriculture industry and each of you play a role in helping make Iowa agriculture so successful.

Visibilidad de las revistas latinoamericanas de bibliotecología y ciencia de la información a través de Google Scholar

Las revistas académico-científicas son uno de los principales canales de comunicación y difusión de los resultados de investigación. Sin embargo no todas tienen el mismo prestigio y grado de influencia en la comunidad científica. De su calidad y visibilidad dependen, en gran medida, las posibilidades de que un trabajo sea conocido, leído y citado. Esta investigación se propone determinar la visibilidad en Google Scholar de un conjunto de revistas latinoamericanas de Bibliotecología y Ciencia de la Información, y clasificarlas según su grado de visibilidad. Utilizando la aplicación Publish or Perish para recuperar las citas de las revistas se calcularon indicadores basados en la citación. Se combinaron técnicas de análisis multivariado de datos para realizar agrupamientos de revistas según su grado de visibilidad, y se elaboraron representaciones gráficas que facilitan la interpretación de los resultados y la identificación de los grupos de revistas con alta, media y baja visibilidad.

Automatic filtering and substantiation of drug safety signals

Drug safety issues pose serious health threats to the population and constitute a major cause of mortality worldwide. Due to the prominent implications to both public health and the pharmaceutical industry, it is of great importance to unravel the molecular mechanisms by which an adverse drug reaction can be potentially elicited. These mechanisms can be investigated by placing the pharmaco-epidemiologically detected adverse drug reaction in an information-rich context and by exploiting all currently available biomedical knowledge to substantiate it. We present a computational framework for the biological annotation of potential adverse drug reactions. First, the proposed framework investigates previous evidences on the drug-event association in the context of biomedical literature (signal filtering). Then, it seeks to provide a biological explanation (signal substantiation) by exploring mechanistic connections that might explain why a drug produces a specific adverse reaction. The mechanistic connections include the activity of the drug, related compounds and drug metabolites on protein targets, the association of protein targets to clinical events, and the annotation of proteins (both protein targets and proteins associated with clinical events) to biological pathways. Hence, the workflows for signal filtering and substantiation integrate modules for literature and database mining, in silico drug-target profiling, and analyses based on gene-disease networks and biological pathways. Application examples of these workflows carried out on selected cases of drug safety signals are discussed. The methodology and workflows presented offer a novel approach to explore the molecular mechanisms underlying adverse drug reactions

El discurso escrito de la Odontología : análisis retórico discursivo de casos clínicos hispanos (1999-2005)

El propósito de este estudio fue identificar y analizar algunos rasgos retóricos discursivos de casos clínicos (CC) odontológicos. Se seleccionó, al azar, un corpus de 40 CC de cuatro revistas odontológicas hispanas (1999-2005). Se encontró que predomina el formato 'introducción, descripción del caso , discusión', siendo la 'descripción del caso' la sección distintiva. Prevalecen las secuencias narrativas y descriptivas en todas las secciones retóricas. Además,hay muy pocas citas, aparecen esencialmente en la 'introcucción' y en la 'discusión' . Se registró el uso de atenuantes en las distintas secciones retóricas del CC: predominó el uso de impersonales, empleados para ocultar el agente de la acción, y aproximadores, para expresar impresión, variabilidad y honestidad. En cuanto al posicionamiento, predominaron el impersonal y plural mayestático. Se concluye que pese a la variabilidad retórica discursiva, el corpus analizado podría definirse como un género discursivo, descriptivo, narrativo e impersonal. El CC es un género importante para las distintas sub-especialidades odontológicas; por lo tanto, los resultados tienen aplicaciones didácticas para la enseñanza del discurso odontológico. Incorporar el CC al currículum de odontología permitiría al estudiante desarrollar las competencias para producir, comprender y publicar este género

The Relationship of Aggregate Durability to Trace Element Content, Interim Report, HR-266, 1984

This report is a brief overview of the recent Iowa Department of Transportation research in the area of durability of Portland cement, concrete under the direction of Wendeli Dubberke. Present plans are to publish a more detailed report on low Portland cement concrete- durability research in January, 1985.

Provision of supplementary materials in Library and Information Science scholarly journals

Purpose This study seeks to analyse the policies of library and information science (LIS) journals regarding the publication of supplementary materials, the number of journals and articles that include this feature, the kind of supplementary materials published with regard to their function in the article, the formats employed and the access provided to readers. Design/methodology/approach The study analysed the instructions for authors of LIS journals indexed in the ISI Journal Citation Reports, as well as the supplementary materials attached to the articles published in their 2011 online volumes. Findings Large publishers are more likely to have a policy regarding the publication of supplementary materials, and policies are usually homogeneous across all the journals of a given publisher. Most policies state the acceptance of supplementary materials, and even journals without a policy also publish supplementary materials. The majority of supplementary materials provided in LIS articles are extended methodological explanations and additional results in the form of textual information in PDF or Word files. Some toll-access journals provide open access to any reader to these files. Originality/value This study provides new insights into the characteristics of supplementary materials in LIS journals. The results may be used by journal publishers to establish a policy on the publication of supplementary materials and, more broadly, to develop data sharing initiatives in academic settings.

Le traduzioni sallustiane di Ludovico Carbone nella Ferrara di Borso e Ercole d'Este : edizione critica, commento linguistico e glossario

La tesi propone l'edizione critica dele traduzioni del Bellum Catilinae e del Bellum Iugurthinum di Sallustio eseguite dall'umanista ferrarese Ludovico Carbone intorno agli anni '70 del Quattrocento. I testi sono accompagnati dagli apparati delle varianti e delle correzioni d'autore; dal testo latino dell'edizione Ernout, con la segnalazione in corsivo delle parti in cui pare evidente che l'umanista aveva di fronte un testo latino diverso; e da note di commento in cui si riportano eventualmente lezioni della tradizione dell'opera sallustiana che potrebbero essere all'origine della traduzione. Nell'introduzione viene delineato il ruolo svolto da Ludovico Carbone nella Ferrara del secondo Quattrocento, tra corte, università e vita cittadina; particolare attenzione è data alle osservazioni sulla lingua italiana dell'umanista e alla sua frequentazione della letteratura in volgare. L'esame della tradizione e della diffusione dell'opera di Sallustio ha lo scopo di comprendere il significato della scelta operata dal traduttore e di cercar di capire che tipo di modello poteva trovarsi di fronte. I due volgarizzamenti sono inseriti nel contesto storico e culturale di Ferrara, che vide in questi anni un'intensa attività di traduzione - spesso su diretta richiesta del principe -, tra i cui autori si distinsero Matteo Maria Boiardo e Niccolò Leoniceno. Inoltre, per una comprensione più completa dell'operazione del Carbone, viene ricostruita la figura del dedicatario delle due traduzioni, Alberto d'Este, e la sua importanza all'interno della storia di Ferrara sia dal punto di vista politico che cultuale; operazione che permette di aggiungere elementi utili a una datazione più precisa delle opere qui pubblicate. Una parte centrale del lavoro riguarda l'analisi delle modalità di traduzione che mostra come l'operazione del Carbone, pur mantenendosi molto rispettosa del testo di partenza, abbia ambizioni letterarie. Lo sforzo del traduttore è incentrato in particolar modo sulla resa dei vocaboli e sul ritmo del periodare. E' interessante notare come l'umanista, la cui prosa latina ha un periodare ampio e ricco di subordinate su modello ciceroniano, in volgare mantenga queste caratteristiche stilistiche solo nelle lettere dedicatorie, mentre nella traduzione il suo stile si uniforma in gran parte al modello di Sallustio. La Nota al testo dà conto dei rapporti tra i manoscritti e dei criteri di edizione delle due opere. Nella Nota linguistica si trova un'analisi sistematica e approfondita della lingua del manoscritto autografo del Catilinario, mentre per gli altri manoscritti sono segnalati gli usi linguistici solo in funzione di una loro collocazione geografica. Un esame contrastivo delle abitudini linguistiche dei copisti rispetto a quelle del Carbone è alla base della scelta del manoscritto da utilizzare per l'edizione del Giugurtino, per il quale non si dispone di un autografo. Un capitolo è dedicato all'analisi delle varianti evolutive del manoscritto londinese contenente il Catilinario. Lo studio del lessico utilizzato nelle traduzioni ha portato alla costituzione del Glossario, che - attraverso un confronto con numerosi vocabolari e testi di area ferrarese o limitrofa - registra e illustra le più significative forme dialettali, i tecnicismi e i latinismi particolarmente crudi, rari o il cui significato si discosta da quello assunto più frequentemente in volgare. Si segnalano alcuni termini le cui prime attestazioni compaiono nella lingua volgare proprio in questo periodo.

O2, the Oberta in Open Access : institutional repository

Tríptic informatiu sobre la publicació de documents amb accés obert en el repositori institucional de la UOC, O2 (La Oberta en obert). Aquest informa sobre quins documents hi poden publicar els membres de la comunitat UOC, com fer-ho i els serveis de valor afegit per a tots els usuaris (web 2.0, subscripció per RSS o correu electrònic, exportació al gestor bibliogràfic Refworks, etc.) i per a la recerca (lligam amb l'aplicació d'avaluació de la recerca GIR i informació del factor d'impacte de la revista a SCOPUS, IN-RECS/IN-RECJ i MIAR).

O2, la Oberta en abierto : repositorio institucional

Tríptic informatiu sobre la publicació de documents amb accés obert en el repositori institucional de la UOC, O2 (La Oberta en obert). Aquest informa sobre quins documents hi poden publicar els membres de la comunitat UOC, com fer-ho i els serveis de valor afegit per a tots els usuaris (web 2.0, subscripció per RSS o correu electrònic, exportació al gestor bibliogràfic Refworks, etc.) i per a la recerca (lligam amb l'aplicació d'avaluació de la recerca GIR i informació del factor d'impacte de la revista a SCOPUS, IN-RECS/IN-RECJ i MIAR).

O2, l'Oberta en obert : el repositori institucional

Tríptic informatiu sobre la publicació de documents amb accés obert en el repositori institucional de la UOC, O2 (La Oberta en obert). Aquest informa sobre quins documents hi poden publicar els membres de la comunitat UOC, com fer-ho i els serveis de valor afegit per a tots els usuaris (web 2.0, subscripció per RSS o correu electrònic, exportació al gestor bibliogràfic Refworks, etc.) i per a la recerca (lligam amb l'aplicació d'avaluació de la recerca GIR i informació del factor d'impacte de la revista a SCOPUS, IN-RECS/IN-RECJ i MIAR).