Achille a Scyros, poëme en six chants.

Mode of access: Internet.

Histoire de la renaissance de la liberte en Italie, de ses progres, de sa decadence et de sa chute /

Mode of access: Internet.

Chef d'oeuvres de l'antiquité sur les beaux-arts : monuments prècieux de la religion des Grecs & des Romains, de leurs sciences, de leurs loix, de leurs usages, de leurs mœurs, de leurs superstitions & de leurs folies, tirés des principaux cabinets de l'Europe /

Includes index.

Men and cities of Italy.

Bibliography at end of each chapter of pt. 1 and 2; "Authorities" at end of pt. 3: p. 311-312.

Études sur les constitutions des peuples libres /

Originally published in Paris, 1836 as first volume of his Études sur les sciences sociales.

Études sur les constitutions des peuples libres.

Mode of access: Internet.

Italie-Rome /

Author supplied from Bib. Nat. (BnF) catalog.

Histoire de la chute de l'Empire romain et du déclin de la civilisation, de l'an 250 à l'an 1000;

Mode of access: Internet.

Political economy and the philosophy of government; selections.

"Historical notice of the life and works of M. de Sismondi, by M. Mignet": p. [1]-24.

Histoire des républiques italiennes du moyen âge,

Mode of access: Internet.

Nouveaux principes d'économie politique,

Mode of access: Internet.

La littérature du refus en pays dominés : entre continuité, invention et utopie

Thèse numérisée par la Direction des bibliothèques de l'Université de Montréal.

La littérature du refus en pays dominés : entre continuité, invention et utopie

Thèse numérisée par la Direction des bibliothèques de l'Université de Montréal.

Common polygenic variation enhances risk prediction for Alzheimer's disease.

The identification of subjects at high risk for Alzheimer’s disease is important for prognosis and early intervention. We investigated the polygenic architecture of Alzheimer’s disease and the accuracy of Alzheimer’s disease prediction models, including and excluding the polygenic component in the model. This study used genotype data from the powerful dataset comprising 17 008 cases and 37 154 controls obtained from the International Genomics of Alzheimer’s Project (IGAP). Polygenic score analysis tested whether the alleles identified to associate with disease in one sample set were significantly enriched in the cases relative to the controls in an independent sample. The disease prediction accuracy was investigated in a subset of the IGAP data, a sample of 3049 cases and 1554 controls (for whom APOE genotype data were available) by means of sensitivity, specificity, area under the receiver operating characteristic curve (AUC) and positive and negative predictive values. We observed significant evidence for a polygenic component enriched in Alzheimer’s disease (P = 4.9 × 10−26). This enrichment remained significant after APOE and other genome-wide associated regions were excluded (P = 3.4 × 10−19). The best prediction accuracy AUC = 78.2% (95% confidence interval 77–80%) was achieved by a logistic regression model with APOE, the polygenic score, sex and age as predictors. In conclusion, Alzheimer’s disease has a significant polygenic component, which has predictive utility for Alzheimer’s disease risk and could be a valuable research tool complementing experimental designs, including preventative clinical trials, stem cell selection and high/low risk clinical studies. In modelling a range of sample disease prevalences, we found that polygenic scores almost doubles case prediction from chance with increased prediction at polygenic extremes.

Meta-cinematic cultism: between high and low culture

ABSTRACT - Meta-cinema can depict film viewers’ attitudes towards cinema and their type of devotion for films. One subcategory of viewers - which I call meta-spectators - is highly specialized in its type of consumption, bordering on obsession. I contend that there are two main varieties of meta-cinematic reception, not altogether incompatible with one another, despite their apparent differences. As both of them are depicted on meta-cinematic products, the films themselves are the best evidence of my typology. My categories of film viewers are the ‘cinephile’, an elite prone to artistic militancy and the adoration of filmic masters; and the ‘fan’, a low culture consumer keen on certain filmic universes and their respective figures and motifs. I will base my rationale on four films that portray such reception practices: Travelling Avant (Jean-Charles Tacchella, 1987, FRA), The Dreamers (Bernardo Bertolucci, 2003, UK/FRA/ITA); Free Enterprise (Robert Mayer Burnett, 1998, USA); Fanboys (2009, Kyle Newman, USA).