Reorganization of the Norfolk and western railroad company. Plan and agreement, dated March 12, 1896 ...

Mode of access: Internet.

The Philadelphia and Reading railroad company. Verbatim report of proceedings at a meeting of share and bond holders, held at the Cannon Street hotel, London, E.C., February 4th, 1881, Sir Henry W. Tyler, M.P., chairman ...

Mode of access: Internet.

Philadelphia and Reading railroad company. Verbatim report of proceedings at a meeting of share and bondholders, held at the Cannon Street hotel, London, E.C., August 5th, 1881. The Right Hon. A.S. Ayrton, chairman.

Mode of access: Internet.

The Philadelphia and Reading railroad company. Letters of Messrs. McCalmont brothers and company. February, 1881.

Cover-title.

Preliminary abstract of railway statistics (steam railways, Railway Express Agency, Inc., and the Pullman Company) ...

At head of title, 1910/11-1911/12: Interstate Commerce Commission; 1912/13-1915/16: Interstate Commerce Commission. Division of Statistics; 1916-53: Interstate Commerce Commission. Bureau of Statistics.

Annual report, Norfolk and Western Railway Company ...

No. 2-5 published in New York.

Annual report of the board of the directors of the Lake Erie and western railroad company to stockholders

Mode of access: Internet.

Newspaper and magazine directory

Mode of access: Internet.

General statement of the affairs of the New York, New Haven and Hartford Railroad Company.

1916- Dec.31 (one unnumbered report for Jan.-Dec. 1916, also 45th for 1915/16)

Employee compensation and payroll hours : women's and misses' suits and coats manufacturing, 1971 /

Cover title.

In Equity no. 169. In the District Court of the United States for the Northern District of California : the Equitable Trust Company of New York, as Trustee, Complainant, against Western Pacific Railway Company, Chester L. Hovey, as Receiver of Boca and Loyalton Railroad Company, and Mercantile Trust Company of San Francisco, as Trustee, Defendants, and Central Trust Company of New York, as Trustee, Intervening Defendant and Cross-complainant.

[V.1.] Proceedings on Master's sale -- [v.2.] Decree of forclosure and sale -- [v.3.] Ancillary decree of foreclosure and sale.

Mechanisms of B and T lymphocyte accumulation in tumor-draining lymph nodes

Thesis (Master's)--University of Washington, 2016-06

Vascular endothelial growth factor-B and retinal vascular development in the mouse

Purpose: Vascular endothelial growth factor-A (VEGF-A) is crucial to retinal vascular growth, both normal and pathological. VEGF-B, recently characterized, is reported to be expressed in retinal tissues, but the importance of VEGF-B to retinal vascular development remained unknown. The aim of this study was to analyse retinal vascular growth in the Vegfb (-/-) knockout mouse. Methods: Retinal vascular growth was measured in Vegfb (-/-) knockout mice raised under normal conditions, and Vegfb (-/-) knockout mice with an oxygen-induced proliferative retinopathy. Wild type Vegfb (+/+) mice served as controls. Vessels were perfused with ink and retinal flatmounts secondarily labelled with FITC-lectin (BS-1, Griffonia simplicifolia ). Area and diameter of retinal growth and retinal vascular growth were recorded over days 0-20, and capillary density and mean diameter recorded from day 17 pups. Results: A variety of techniques confirmed that Vegfb (+/+) mice expressed VEGF-B and that VEGF-B expression was absent in Vegfb (-/-) mice. Vegfb (-/-) mice raised in room air showed no significant differences from Vegfb (+/+) controls. No differences were found in oxygen-induced retinopathy between Vegfb (-/-) and Vegfb (+/+) pups in either the extent of the initial oxygen-induced ablation, or in the regrowth of retinal vessels or vitreal (neovascular) sprouts; vitreal sprouts are important markers of the abnormal proliferative response, and are maximally expressed on day 17 in this model of oxygen-induced retinopathy. Conclusions: These results indicate that a lack of VEGF-B does not significantly affect development of the retinal vasculature under normal conditions, nor does it appear to affect the proliferative retinal responses seen in oxygen-induced retinopathy.

Cross-reactive recognition of human and primate cytomegalovirus sequences by human CD4 cytotoxic T lymphocytes specific for glycoprotein B and H

Although the importance of CD4(+) T cell responses to human cytonnegalovirus (HCMV) has recently been recognized in transplant and immunosuppressed patients, the precise specificity and nature of this response has remained largely unresolved. In the present study we have isolated CD4(+) CTL which recognize epitopes from HCMV glycoproteins gB and gH in association with two different HLA-DR antigens, DRA1*0101/DRB1*0701 (DR7) and DRA1*0101/DRB1*1101 (DR11). Comparison of amino acid sequences of HICMV isolates revealed that the gB and gH epitope sequences recognized by human CD4(+) T cells were not only conserved in clinical isolates from HCMV but also in CMV isolates from higher primates (chimpanzee, rhesus and baboon). Interestingly, these epitope sequences from chimpanzee, rhesus and baboon CMV are efficiently recognized by human CD4(+) CTL. More importantly, we show that gB-specific T cells from humans can also efficiently lyse pepticle-sensitized Patr-DR7(+) cells from chimpanzees. These findings suggest that conserved gB and gH epitopes should be considered while designing a prophylactic vaccine against HCMV. In addition, they also provide a functional basis for the conservation of MHC class 11 lineages between humans and Old World primates and open the possibility for the use of such primate models in vaccine development against HCMV.