Efeito da desinfecção química e do envelhecimento acelerado sobre a, estabilidade dimensional, reprodução e manutenção de detalhes, dureza “Shore A”, deterioração e estabilidade de cor de silicone para próteses faciais com distintas pigmentações

Pós-graduação em Odontologia - FOA

Fazendo arte na literatura: um panorama lúdico e estético da literatura infantil e juvenil brasileira

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Efeito alelopático de extratos de Amburana cearensis (fr. All.) A. C. Smith sobre a germinação emergência de plântulas

Pós-graduação em Ciências Biológicas (Botânica) - IBB

A violência contra a mulher e a proteção social: estudo sobre as ações da Prefeitura Municipal de Belém destinadas às mulheres

Aborda as temáticas da violência e das políticas públicas concebidas para a proteção à mulher. A pesquisa se prende em duas gestões no Município de Belém, concentra seu foco de análise nas políticas de Saúde, Assistência Social e Justiça. O objetivo é avaliar o desempenho dos gestores, um do Partido da Frente Liberal (tipificado do ponto de vista ideológico como Partido de Direita) e outro do Partido dos Trabalhadores (caracterizado como Partido de Esquerda) no tocante à proteção social à mulher. A abordagem da temática baseia-se em pesquisa bibliográfica e documental, neste último adotando como fonte principal os relatórios anuais de atividades e as mensagens dos respectivos gestores à Câmara Municipal de Belém. A análise comparativa sobre o desempenho dos prefeitos na condução das políticas públicas destacadas, aponta para uma discreta vantagem da gestão do PT notadamente nas políticas de Saúde e de Assistência Social. Cabe, porém, ressalvar que o avanço nestas políticas coincide e está condicionado a implantação dos SUS e do sistema descentralizado e participativo da assistência social, que ocorre de forma federada sob a coordenação das instâncias do governo federal.

O poder municipal e as práticas mercantilistas no mundo colonial: um estudo sobre a Câmara Municipal de São Paulo – 1780-1822

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

TV Legislativa: TV Câmara de Ribeirão Preto e accountability

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Regulamentação Sanitária de Medicamentos

A regulamentação sanitária de medicamentos é uma das oito diretrizes da Política Nacional de Medicamentos. Trata-se da fiscalização e regulamentação de registro de medicamentos e da autorização de funcionamento desde os produtores até o varejo de medicamentos, bem como das restrições àqueles sujeitos a controle especial. A regulamentação sanitária de medicamentos tem como objetivo garantir eficácia, segurança, qualidade e custo aos produtos farmacêuticos. Os estudos clínicos dos medicamentos de Referência, a bioequivalência ou biodisponibilidade relativa e testes de equivalência dos medicamentos similares e genéricos são meios de avaliar a eficácia e a segurança. A qualidade é garantida lote a lote pelas Boas Práticas de Fabricação e Controle dos produtos farmacêuticos e a certificação da empresa pela ANVISA. O custo é avaliado pela câmara técnica de medicamento (CMED), que estabelece os critérios para fixação e ajuste de preços dos produtos farmacêuticos. No pós-registro, a efetividade, segurança e qualidade dos produtos são avaliadas por meio das comprovações exigidas na renovação do registro e, principalmente, pelo programa de farmacovigilância. Palavras-chave: Registro de Produtos. Medicamentos de Referência. Medicamentos Similares. Medicamentos Genéricos. Alteração de Registro de Produtos. ABSTRACT Health Regulations for Drugs The health regulation of drugs is one of eight guidelines issued within the National Drug Policy. It refers to the supervision and regulation of drug registration and the approval of operations, from the manufacturers to the retailers of medicines, as well as the restrictions that apply to drugs under special control. The health regulation of medicines is aimed at controlling the effectiveness, safety, quality and cost of pharmaceutical products. Clinical studies of brand-name (innovator) medicines, bioequivalence or relative bioavailability and the equivalence tests of generic and ‘similar’ brand-name drugs are means used to assess efficacy and safety. Quality is assured on a batch-to-batch basis by compliance with the Good Manufacturing Practices and Control of pharmaceutical products and by the certification of companies offered by ANVISA. The cost of a medicine is assessed by the Technical Chamber of Medicine (CMED), which establishes the criteria for setting and adjusting the prices of pharmaceutical products. After registration, the effectiveness, safety and quality of products are monitored by means of the tests required on renewal of registration and especially by the pharmacovigilance program. Keywords: Product Registration. Original Brand-name Drugs. Similar Drugs. Generic Drugs. Modification of Product Registration.

Modelagem de motor de combustão internae simulação do processo de queima de combustível

The internal combustion engine is a heat engine widely used in the automotive industry. In order to better understand its behavior many models in the literature have been proposed in the last years. The 0-D thermodynamic model is a fairly simple tool but it is very useful to understand the phenomenon of combustion inside the chamber of internal combustion engines. In the first phase of this work, an extensive literature review was made in order to get information about this kind of analysis and, after this, apply them in a model able to calculate the instantaneous temperature and pressure in one zone of the combustion chamber of a diesel engine. Therefore some considerations were made with the aim of increasing the accuracy of the model in predicting the correct behavior of the engine, adding the combined effects of heat transfer, leakage and injection. In the second phase, the goal was to study the internal flow of a three-dimensional model of an internal combustion engine. In order to achieve this goal the software Solidworks was used to create the geometries of an engine and the suite of softwares Ansys was used to create the moving mesh (ICEM CFD and CFX-Pre) and to solve the CFD problem (Ansys CFX code). The model was able to perform the air flow simulation during the four-stroke cycle of an engine: admission, compression, expansion and exhaust. The results obtained from both models were suitable and they open a new range of possibilities for future researches on the field

Variação temporal e espacial da taxa de sedimentação e das características limnológicas na microbacia do córrego da Barrinha, no município de Pirassununga, SP

Studies regarding the quality and quantity of water have become more and more important because of the increasing negative environmental impacts occurred and their scarcity increase as well. At the Center of Tropical Fish Research (Centro de Pesquisas de Peixes Tropicais - CEPTAlIBAMA) located in the city of Pirassununga, SP, there is a dam named Represa Velha which supplies 128 tanks that are fish hatcheries. This dam takes in part of the Barrinha stream micro-basin where it has been observed strong impacts due to the deforestation of its support forest, as well an the intensive agricultural activities in the neighboring areas. There has been established and distributed 13 points of water-collectors disposed inside the stream and the dam. The water samples were taken from the stream only from its surface because of the low depth and, inside. In the dam, the water samples were taken at the water column, at a 50cm distance over the sediment. In every point of collection inside the dam, it was placed a chamber of sedimentation, vertically in the water column at a 70% height from the total depth. The collections took place during the dry/cold and raining/warm periods of the years 2000 and 2001. Then, it were analyzed the physical, physical-chemical, chemical and micro-biological parameters of the water samples. The obtained results were statistically analyzed throughout the SAS system (Statistical Analisys System). Parameters such as total phosphate, nitrate, nitrite and turbidity were within the established limits for the Class 2 water, according to the n° 20/1986 CONAMA Resolução. However, the total and Escherichia coli coliforms, mainly inside the Barrinha stream, had showed values above of the established limits for the same... (Complete abstract click electronic access below)

Modelo de conductancia hidráulica de la dentina humana ex vivo

The main objective of this work was to mount and test an experimental model to measure the hydraulic conductance of ex vivo dentin. Seventeen healthy third molars, with indication of extraction of healthy donors aged between 15 and 30 years were obtained by informed consent. After cleaning them, disinfecting them, including them in resin epoxy and cutting them, there were 17 samples of dentin, corresponding to a disk of resin with a coronal section of tooth showing the dentin exposed on both sides of it. Three machines to measure the hydraulic conductance of the dentin were assembled according to the description of the model of Pashley. Samples were installed in a Chamber of diffusion, connected by using silicone tubes to a graduated transfer pipette and a 20cm water column. Through the displacement of a bubble of water in the inside of the pipette, the hydraulic conductance of each sample was measured 3 times on the 14th, 21st, 28th and 35th day post extraction. The data were tabulated and analyzed statistically. There is no SS difference in the rate of flow of a measured sample in the three machines (p=0.5937). There is no SS difference in measurements of the hydraulic conductance of 13 samples of human dentin measured in days 14, 21, 28 and 35 postextraction (p=0.0704). It is possible to mount an experimental model to study the hydraulic conductance of dentin ex vivo, based on the model of Pashley. The model seems to be reliable, but more research is needed in order to validate its reliability.

Morfologia do estômago do cervo-do-pantanal (Blastocerus dichotomus, Illiger 1815)

Based on the lack of information regarding the morphology of marsh deer, this work aims to describe some morphological aspects of the gastric chamber in this species, collaborating with future investigations, mainly related to rational handling in this cervid. This work aimed to describe the morphology of the gastric chamber of the marsh deer, characterizing the external and internal macroscopical details and the microscopical architecture of these structures by light microscopy. Macroscopically, the marsh deer stomach is formed by the rumen, reticulum, omasum and abomasum similar to the domestic ruminants. Microscopically, rumen and abomasum are similar to the domestic ruminants. The reticulum and the omasum, however, present specific characteristics such as keratin on the top of the reticulum, small epithelial projections and omasum folds covered with discrete papillae.

Engine LES with fuel-spray modeling

Pós-graduação em Engenharia Mecânica - FEG

Proposta de adequação à construção sustentável: tecnologias e alternativas para instituições de ensino

Due to the huge impact negative on the environmental caused by the civil construction, the university plays a majorital role in the proposal of studies and projects that aim the sustainable building. Nowadays, it has been noted the great demand for projects which contain a systemic focus in the tripod of the sustainable development, that is to say, more and more the consumers are demanding that the final result of a project contemplate the social, economic and environmental areas. According to the National Industry Confederation (CNI) and the Brazilian Chamber of the Industry and the Construction (CBIS), the goal for 2020 is that the constructions have an environmental performance 20% higher in comparison to the actual one, starting with an index defined by many indicators, such as: water consumption, energy, residues generation and social-environmental performance of the bought products. In this case, the theme of the project comes around the adequation of scholar institutions to the sustainable construction through simple changes of tecnologies and habits aiming the growth of the environmental eficiency of the enterprise and, consequently, the improve of sustainable practices inside the institution. Once the change is proposed, it will be furnished datas liable of reproduction for the adequation of others scholar institutions, according to it's necessity or interest. After the realization of the studies, it was possible to notice that the environmental performance of a scholar institution can be improved through the implantation of tecnologies of fast return in the investment, such as: flow reducers, rain water reuse system, green roof, retrofit of lamps and execution of a photovoltaic system. Besides the fast return of investment, the monthly economy of the applied tecnologies combined can reach 75% when compared to the actual spending with water and electric energy

Estudo da combustão do óleo pirolítico de pneus

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Entwicklung, Aufbau und Charakterisierung eines neuartigen Ionenfallen-Massenspektrometers für Aerosolpartikel (AIMS)

Im Rahmen der Arbeit wurde ein neuartiges Aerosol-Ionenfallen-Massenspektrometer (AIMS) aufgebaut und umfassend charakterisiert. Mit dem AIMS kann die chemische Zusammensetzung der verdampfbaren Komponente (bei etwa 600 °C) von Aerosolpartikeln quantitativ und on-line bestimmt werden. Die Durchmesser der Teilchen, die analysiert werden können, liegen zwischen etwa 30 und 500 nm. Der experimentelle Aufbau greift auf ein bereits gut charakterisiertes Einlasssystem des Aerodyne Aerosol-Massenspektrometers (AMS) zurück, das einen Partikeleinlass, bestehend aus einer kritischen Düse und einer aerodynamischen Linse, einen Verdampfer für die Aerosolteilchen und eine Elektronenstoß-Ionenquelle enthält. Das kommerzielle AMS verwendet entweder ein lineares Quadrupol-Massenfilter (Q-AMS) oder ein Flugzeit-Massenspektrometer (ToF-AMS). Im AIMS hingegen wird eine dreidimensionale Ionenfalle als Massenanalysator eingesetzt. Dadurch eröffnen sich unter anderem Möglichkeiten zur Durchführung von MSn-Studien und Ionen/Molekül-Reaktionsstudien. Das Massenspektrometer und wichtige Teile der Steuerungselektronik wurden am Max-Planck-Institut für Chemie in Mainz entworfen und hergestellt. Das AIMS wird von einem PC und einer Software, die in der Programmiersprache LabVIEW verfasst ist, gesteuert. Aufgrund seiner Kompaktheit ist das Instrument auch für den Feldeinsatz geeignet. Mit der Software Simion 7.0 wurden umfangreiche Simulationsstudien durchgeführt. Diese Studien beinhalten Simulationen zur Ermittlung der optimalen Spannungseinstellungen für den Ionentransfer von der Ionenquelle in die Ionenfalle und eine Abschätzung der Sammeleffizienz der Ionenfalle, die gut mit einem gemessenen Wert übereinstimmt. Charakterisierungsstudien zeigen einige instrumentelle Merkmale des AIMS auf. Es wurde beispielsweise ein Massenauflösungsvermögen von 807 für m/z 121 gefunden, wenn eine Analyserate von 1780 amu/s verwendet wird. Wird die Analyserate verringert, dann lässt sich das Massenauflösungsvermögen noch erheblich steigern. Bei m/z 43 kann dann ein Wert von > 1500 erzielt werden, wodurch sich Ionenfragmente wie C2H3O+ (m/z 43.0184) und C3H7+ (m/z 43.0548) voneinander trennen lassen. Der Massenbereich des AIMS lässt sich durch resonante Anregung erweitern; dies wurde bis zu einer Masse von 1000 amu getestet. Kalibrationsmessungen mit laborgenerierten Partikeln zeigen eine hervorragende Linearität zwischen gemessenen Signalstärken und erzeugten Aerosol-Massenkonzentrationen. Diese Studien belegen im Zusammenhang mit den gefundenen Nachweisgrenzen von Nitrat (0.16 μg/m³) und Sulfat (0.65 μg/m³) aus Aerosolpartikeln, dass das AIMS für quantitative Messungen von atmosphärischem Aerosol geeignet ist. Ein Vergleich zwischen dem AIMS und dem Q-AMS für Nitrat in städtischem Aerosol zeigt eine gute Übereinstimmung der gefundenen Messwerte. Für laborgenerierte Polystyren-Latexpartikel wurde eine MS/MS-Studie unter der Anwendung von collision induced dissociation (CID) durchgeführt. Das Verhältnis von Fragmentionen zu Analytionen wurde zu einem Wert von > 60% bestimmt. In der Zukunft können ähnliche MS/MS-Studien auch für atmosphärische Aerosolpartikel angewandt werden, wodurch sich neue Perspektiven für die Speziation von Aerosolbestandteilen eröffnen. Dann sollen vor allem Kondensationsprozesse, das heißt die Bildung von sekundärem Aerosol, detailliert untersucht werden.