Vasoconstrictor effect of Africanized honeybee (Apis mellifera L.) venom on rat aorta

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Dor abdominal crônica, dispepsia não ulcerosa e infecção pelo Helicobacter pylori em crianças e adolescentes

Pós-graduação em Patologia - FMB

O uso do peritônio de paca conservado em solução supersaturada de açúcar a 300% ou glicerina a 98% implantados na parede abdominal de ratos

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaiação da Dor e da Postura em Pacientes com Lombalgia Submetidos a Dois Protocolos de Fortalecimento Abdominal

Introduction: the lumbar spine is the main part of the body responsible for the support of the loads, where approximately half of body weight is in stable balance. This support relates to the action of abdominal muscles, of great importance in the balance of that region. The existence of abdominal muscle weakness, such won’t perform its function, may induce pathological postural attitude, that predispose the pain. Objective: to compare the effects of two abdominal strengthening protocols on pain and postural alignment in individuals with low back pain. Method: participated of the study 21 individuals of both genders, with ages between 19 and 25 years old (average 21,8±1,5) and average Body Mass Index (BMI) 21,9 (±2,48), divided randomly in isometric abdominal stimulation group (n=8), abdominal strengthening group (n=7) and control group (n=6). They realized eight sessions of strengthening, when responded Visual Analogue Scale (VAS) before and after each intervention. The control group (n=6) had no intervention. The postural data had been analyzed by photogrammetry. Results: Pain and posture data were analyzed using paired t test, with signifi cance index of 5%. Postural angles had no signifi cant differences (p>0,05) from all angles analyzed after the intervention to none of the groups. For pain values, a signifi cant decrease (p<0,05) was observed since the fi fth session in patients who were treated by the abdominal exercises protocol, and the fi rst session in patients who were treated by the isometric abdominal stimulation protocol. However, this decrease in pain was immediate, not lasting along the treatment sessions, in both protocols. Conclusion: the proposed protocols did not interfere in postural alignment. They were effective to decrease pain in a same session, once the isometric was the most effective, but they weren’t effective in preserving the improves over time.

Análise comparativa da mobilidade tóraco-abdominal em relação ao índice de massa corporal em crianças

Introdução: O índice de massa corporal elevado no compartimento toraco-abdominal promove alterações no sistema respiratório interferindo nos volumes e capacidades e consequentemente na troca gasosa. Objetivo: Analisar comparativamente a mobilidade tóraco-abdominal relacionando ao índice de massa corporal em crianças. Metodologia: Trata-se de um estudo do tipo transversal com abordagem quantitativa e descritiva. A amostra constou de 70 crianças com idade entre 8 e 12 anos de ambos os sexos e com o índice de massa corporal variável. Foi realizada a verificação da altura, peso, expansibilidade destas crianças em seguida classificadas em três grupos em função dos seus índices de massa corporal: eutróficos (57,1%), com sobrepeso (15,7%) e obesos (27,1%). Resultados: Os resultados obtidos apresentaram diferenças entre o grupo dos eutróficos e dos obesos, indicando, nesta perspectiva, que a mobilidade na região axilar e xifoideana são mais elevadas no grupo dos eutróficos, quando comparado ao dos obesos. Conclusão: Portanto conclui-se que o índice de massa corporal está relacionado a alterações na expansibilidade tóraco abdominal de crianças.

Abdominal muscle strength is related to the quality of life among older adults with lumbar osteoarthritis

The aim of the present study was to determine the association between abdominal muscle strength and quality of life among older adults with lumbar osteoarthritis. A blind, cross-sectional study was conducted involving 40 older adults: 20 with lumbar osteoarthritis (12 women and 8 men, mean age of 65.90 ± 4.80 years) and 20 controls (14 women and 6 men, mean age of 67.90 ± 4.60 years). The volunteers were submitted to an abdominal muscle strength test. Quality of life was evaluated using the SF-36 questionnaire. Both abdominal muscle strength and quality of life scores were significantly lower in the group with lumbar osteoarthritis in comparison to the controls (p < 0.05). Moreover, significant and positive associations were found between abdominal muscle strength and the subscales of the SF-36 questionnaire (p < 0.05, 0.421 ≥ rs ≤ 0.694). Based on the present findings, older adults with lumbar osteoarthritis with greater abdominal muscle strength have a better quality of life.

Vagal afferent control of abdominal expiratory activity in response to hypoxia and hypercapnia in rats

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Abdominal ultrasound alterations in dogs with lymphoma

The aim of this study was to evaluate abdominal ultrasound images of dogs diagnosed with lymphoma. Seventy cases of dogs with lymphoma were analyzed. The animals selected were diagnosed with lymphoma which was confirmed by citology or histopathology. The most common sonographic alterations were abdominal lymphadenopathy (57.1%), hepatomegaly (54.2%) and splenomegaly (51.4%). Of the animals that had a cytology done of superficial lymph nodes, 82,8% showed diffuse sonographic changes in the liver, 54.5% had normal sonographic appearance in the spleen and enlargement of the medial iliac lymph nodes. Considering the results, we conclude that canine lymphoma is a complex disease and that it requires several laboratory tests for a correct diagnosis and prognosis.

The intricate role of mast cell proteases and the annexin A1-FPR1 system in abdominal wall endometriosis

Endometriosis is a continuous and progressive disease with a poorly understood aetiology, pathophysiology and natural history. This study evaluated the histological differences between eutopic and ectopic endometria (abdominal wall endometriosis) and the expression of mast cell proteases (tryptase and chymase), annexin A1 (ANXA1) and formyl peptide receptor 1 (FPR1). Ectopic endometrium from 18 women with abdominal wall endometriosis and eutopic endometrium from 10 women without endometriosis were obtained. The endometrial samples were analysed by histopathology, immunohistochemistry and ultrastructural immunogold labeling to determine mast cell heterogeneity (tryptase and chymase positive cells) and the expression levels of ANXA1 and FPR1. Histopathological analysis of the endometriotic lesions showed a glandular pattern of mixed differentiation and an undifferentiated morphology with a significant influx of inflammatory cells and a change in mast cell heterogeneity, as evidenced by a significant increase in the number of chymase-positive cells and endogenous chymase expression. The undifferentiated glandular pattern of endometriotic lesions was positively associated with a marked increase and co-localization of ANXA1 and FPR1 in the epithelial cells. In conclusion, the co-upregulated expression of mast cell chymase and ANXA1–FPR1 system in ectopic endometrium suggests their involvement in the development of endometriotic lesions.

Efeitos da exposição pré-natal ao etanol e ao chumbo, isoladamente e em associação, sobre a pressão arterial e a reatividade da aorta de ratos recém-desmamados

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Vias de sinalização endotelial α2, AT1, e AT2 sobre a reatividade da aorta de ratos após consumo de etanol e exposição ao estresse, isoladamente e em associação

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Dopplerfluxometria e avaliação morfométrica do fígado, baço, rins e grandes vasos abdominais de onças pardas (Puma concolor) da região Campo Grande, Mato Grosso do Sul, Brasil

Pós-graduação em Biotecnologia Animal - FMVZ

Relationship between therapeutic alliance and deep abdominal muscle recruitment in nonspecific low back pain sufferers

Chronic low back pain is a difficult condition to be treated. As some patients respond positively to treatment and others do not present any improvements, one can think there are others conditional factors that need to be elucidated. By means of this study, we sought to investigate the association between the occurrence of the formation of a positive relationship between patient and therapist, assessed by the therapeutic alliance inventory, and the adequate recruitment of the deep abdominal muscles, as well as to verify the effect of a protocol intervention based on motor control exercises on levels of pain and disability. The recruitment of the transverse abdominal and internal oblique muscles was examined by ultrasound imaging in 12 subjects with nonspecific chronic low back pain before and after implementation of a protocol for motor control exercises, with subsequent application of the therapeutic alliance inventory questionnaire. No association was found between the level of therapist/patient alliance and muscle recruitment. The proposed protocol was effective in reducing the levels of pain and disability; however, recruitment of transverse abdominal and internal oblique muscles showed no significant changes in the end of the intervention. Based on these findings, we verified that the therapeutic alliance has no association with muscle recruitment in the short term. However, although there were no changes in muscle recruitment after the intervention program, the level of pain and disability was reduced.

Peritoneal response to abdominal surgery: the role of equine abdominal adhesions and current prophylactic strategies

Intra-abdominal adhesions constitute a significant clinical and surgical problem that can lead to complications such as pain and bowel occlusion or subocclusion. These adhesions are frustrating and potentially fatal, representing a major postoperative complication in abdominal surgery. It is estimated that 32% of horses undergoing laparotomy will present clinical symptoms due to adhesions, but the true prevalence is not known because a large proportion of animals with postoperative recurrent colics are medically treated or submitted to euthanasia without necropsy. Adhesions are highly cellular, vascularized, dynamic structures that are influenced by complex signaling mechanisms. Understanding their pathogenesis could assist in applying better therapeutic strategies and in developing more effective antiadhesion products. Currently, there are no definitive strategies that prevent adhesion formation, and it is difficult to interpret the results of existing studies due to nonstandardization of an induction model and evaluation of their severity. The best clinical results have been obtained from using minimally traumatic surgical techniques, anti-inflammatory agents, antimicrobials, anticoagulants, and mechanical separation of serosal surfaces by viscous intraperitoneal solutions or physical barriers. This paper aims to review adhesion formation pathogenesis, guide the understanding of major products and drugs used to inhibit adhesion formation, and address their effectiveness in the equine species.

The hindlimb arterial vessels in lowland paca (Cuniculus paca, Linnaeus 1766)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)