Examining the relationship among genes, attention bias to emotion, and depression in youth

The investigation of biologically initiated pathways to psychological disorder is critical to advance our understanding of mental illness. Research has suggested that attention bias to emotion may be an intermediate trait for depression associated with biologically plausible candidate genes, such as the serotonin transporter (5-HTTLPR) and catechol-o-methyl-transferase (COMT) genes, yet there have been mixed findings in regards to the precise direction of effects. The experience of recent stressful life events (SLEs) may be an important, yet currently unstudied, moderator of the relationship between genes and attention bias as SLEs have been associated with both gene expression and attention to emotion. Additionally, although attention biases to emotion have been studied as a possible intermediate trait associated with depression, no study has examined whether attention biases within the context of measured genetic risk lead to increased risk for clinical depressive episodes over time. Therefore, this research investigated both whether SLEs moderate the link between genetic risk (5-HTTLPR and COMT) and attention bias to emotion and whether 5-HTTLPR and COMT moderated the relationship between attention biases to emotional faces and clinical depression onset prospectively across 18 months within a large community sample of youth (n= 467). Analyses revealed a differential effect of gene. Youth who were homozygous for the low expressing allele of 5-HTTLPR (S/S) and had experienced more recent SLEs within the last three months demonstrated preferential attention toward negative emotional faces (angry and sad). However, youth who were homozygous for the high expressing COMT genotype (Val/Val) and had experienced more recent SLEs showed attentional avoidance of positive facial expressions (happy). Additionally, youth who avoided negative emotion (i.e., anger) and were homozygous for the S allele of the 5-HTTLPR gene were at greater risk for prospective depressive episode onset. Increased risk for depression onset was specific to the 5-HTTLPR gene and was not found when examining moderation by COMT. These findings highlight the importance of examining risk for depression across multiple levels of analysis, such as combined genetic, environmental, and cognitive risk, and is the first study to demonstrate clear evidence of attention biases to emotion functioning as an intermediate trait predicting depression.

Conducta agresiva e inteligencia emocional en la adolescencia

Son escasos los estudios que analizan la relación entre conducta agresiva e inteligencia emocional. Este estudio examina la relación entre inteligencia emocional rasgo y los componentes motor (agresividad física y agresividad verbal), cognitivo (hostilidad) y afectivo/emocional (ira) de la conducta agresiva. El Trait Emotional Intelligence Questionnaire-Adolescents Short Form (TEIQue-ASF) y el Aggression Questionnaire Short version (AQ-S) fueron administrados a una muestra de 314 adolescentes (52.5% chicos) de 12 a 17 años. Los resultados indicaron que los adolescentes con altas puntuaciones en conducta agresiva física, verbal, hostilidad e ira presentaron puntuaciones significativamente más bajas en inteligencia emocional rasgo que sus iguales con puntuaciones bajas en conducta agresiva física, verbal, hostilidad e ira. Este patrón de resultados fue el mismo tanto para la muestra total como para chicos, chicas y los grupos de edad de 12-14 años y 15-17 años. Además, en la mayoría de los casos se hallaron tamaños del efecto grandes apoyando la relevancia empírica de estas diferencias.

Capacidad predictiva de la ira sobre la ansiedad escolar en estudiantes chilenos de Educación Secundaria

La ira y la ansiedad están relacionadas a través de la vulnerabilidad biológica subyacente en ambos constructos, ya que los individuos reaccionan ante una amenaza con ira o ansiedad. Pero ¿tiene la ira la capacidad para predecir la ansiedad? En este estudio nos hemos propuesto analizar esta capacidad predictiva de la ira sobre la ansiedad escolar en una muestra de 1131 estudiantes chilenos de Educación Secundaria, 560 chicos y 571 chicas (49,51% y 51,49%, respectivamente) todos ellos con edades comprendidas entre los 13 y los 18 años (M=15.30; DE=1.10). La expresión de la ira se midió con el State-Trait Anger Expression Inventory for Children and Adolescents (STAXINA) y la Ansiedad Escolar con el Inventario de Ansiedad Escolar (IAES). Los análisis de regresión logística revelaron que altas puntuaciones en sentimientos de ira, temperamento de ira, expresión interna de ira, ira-estado e ira-rasgo predicen la alta ansiedad. Estos resultados sugieren la necesidad de diseñar y desarrollar programas educativos que ayuden a los estudiantes a canalizar la expresión de la ira y disminuyan los niveles de ansiedad escolar.

O marca-passo das emoções no ritmo de crianças portuguesas com necessidades educativas especiais (estudo de caso)

Estudo de caso (metodologia qualitativa) realizado em 2013sobre inteligência emocional em alunos portugueses, frequentando 1.º ciclo educação básica, com idades de 6-7 anos de 2 escolas urbanas:2 crianças (M=microcefalia, A=autismo atípico); 2 crianças (N= criança normal, H= perturbação de hiperatividade com défice de atenção). Os objetivos pretenderam: Demonstrar a importância das emoções na aprendizagem; identificar e lidar com as emoções em situações; propor estratégias para cada criança, aquando dos resultados obtidos com aplicação do teste projetivo e utilização material didático. Metodologia: atividades com ―Uma caixa cheia de emoções‟; prova projetiva ―Era uma vez…‖ Teresa Fagulha; ficha de anamnese aos pais; análise documental aos processos; observação participante; notas de campo e triangulação. Os resultados permitiram estabelecer estratégias para diminuir os fatores de distratibilidade, facilitar a atenção com material visualmente atrativo e manuseável e fornecer instruções acompanhadas de observação. Houve dificuldades nos sujeitos em identificar a ‘ira’ e ‘raiva‘.

Deposition of Andrew Eliot against Nathan Prince, Nov. 26, 1741

In this deposition, Eliot describes Prince's anger at John Winthrop's selection as Hollis Professor of Mathematics and Natural Philosophy, which he believed was done "to vex and torture" him. Eliot claims that Prince said: "they have chosen that Boy Winthrop professor, I could teach him his A. B. C. in the Mathematicks, they want to get me away from College."

Commonplace book of Hector Orr, 1789-1804

Hector Orr began recording entries in this commonplace book during his first year as a student at Harvard and continued writing in the volume sporadically until 1804. The entries written while he was a student, from 1789 to 1792, include themes written on the following topics: Time, Discontent, Patriotism, Virtue, Conscience, Patience, Avarice, Compassion, Mortality, Self-knowledge, Benevolence, Morning, Anger, Profanity, Bribery, Autumn and Winter, Hermitage, Conscience and Anticipation. He also wrote detailed entries about the forensic disputations in which he and his classmates participated, explaining both the affirmative and negative positions. One of these disputations involved discussion of the Stamp Act, which was then quite recent history. Orr's entries about the disputations list the names of students involved and specify their position in the argument.

Letter from Samuel Willard, Deerfield, Massachusetts, to Susanna Willard, Belchertown, Massachusetts, November 10, 1813

Willard discusses an issue regarding ordination procedures with the council at Greenfield: “I did not think it my duty to quit the ground, but defended my rights & told them with the utmost plainness, tho’ without anger, what I tho’t of their measures.”

John Warren's copy of votes from a meeting of the Boston Medical Society, 1784 May 3

This document lists the eleven votes cast at a meeting of the Boston Medical Society on May 3, 1784. It was authorized as a "true coppy" by Thomas Kast, the Secretary of the Society. The following members of the Society were present at the meeting, all of them doctors: James Pecker, James Lloyd, Joseph Gardner, Samuel Danforth, Isaac Rand, Jr., Charles Jarvis, Thomas Kast, Benjamin Curtis, Thomas Welsh, Nathaniel Walker Appleton, and doctors whose last names were Adams, Townsend, Eustis, Homans, and Whitwell. The document indicates that a meeting had been held the previous evening, as well (May 2, 1784), at which the topics on which votes were taken had been discussed. The votes, eleven in total, were all related to the doctors' concerns about John Warren and his involvement with the emerging medical school (now Harvard Medical School), that school's relation to almshouses, the medical care of the poor, and other related matters. The tone and content of these votes reveals anger on the part of the members of the Boston Medical Society towards Warren. This anger appears to have stemmed from the perceived threat of Warren to their own practices, exacerbated by a vote of the Harvard Corporation on April 19, 1784. This vote authorized Warren to apply to the Overseers of the Poor for the town of Boston, requesting that students in the newly-established Harvard medical program, where Warren was Professor of Anatomy and Surgery, be allowed to visit the hospital of the almshouse with their professors for the purpose of clinical instruction. Although Warren believed that the students would learn far more from these visits, in regards to surgical experience, than they could possibly learn in Cambridge, the proposal provoked great distrust from the members of the Boston Medical Society, who accused Warren of an "attempt to direct the public medical business from its usual channels" for his own financial and professional gain.

Doenças cardiovasculares, padrão de comportamento tipo A, hostilidade e ira

Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2014

Europe in limbo while the UK descends into chaos. EPC Post-Summit Commentary, 30 June 2016

The EU Summit and the separate meeting of the EU27 without the UK on 28/29 June 2016 demonstrated that the EU is in limbo. Following the initial shock, frustration and anger after the unexpected result of the UK ‘in/out’ referendum, the future relationship between the European Union (EU) and the United Kingdom (UK) monopolised the meetings of EU leaders. The EU has entered uncharted waters and leaders are struggling to figure out how exactly to deal with the manifold (potential) consequences of the ‘Brexit crisis’. Despite the many uncertainties, the EU27 managed to reach some common lines, trying to convey four key messages, although the final outcome of the crisis and its effects on the Union’s overall future are still very unclear:

The shepheards calender : conteining twelue æglogues proportionable to the twelue monthes : entituled, to the noble and vertuous gentleman, most worthie of all titles, both of learning and chiualry, Maister Philip Sidney.

Fourth edition.

Nouveaux éléments d'anatomie chirurgicale... /

Índice.

De la cautérisation actuelle dans le traitement des maladies chirurgicales /

Memoria presentada al concurso para la cátedra en la Universidad de París, Facultad de Medicina (Sección de Cirugía)