973 resultados para Allen, Ann Isabella Barry


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Welsch (Projektbearbeiter): Verbot des Tragens geladener Waffen für diejenigen Mobilgardisten, welche nicht direkt vor dem Feind Dienst tun

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Welsch (Projektbearbeiter): Verhängung der Todesstrafe durch Erschießen in Fällen von Plünderung

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Welsch (Projektbearbeiter): Vorladung der Vertrauensmänner sämtlicher Kompanien der Nationalgarde, Mobilgarde und der Akademischen Legion zwecks Abstimmung über die Fortführung des bewaffneten Widerstandes gegen Windisch-Graetz

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Welsch (Projektbearbeiter): Bekanntmachung über die Zulassung des freien Verkehrs aus und nach der Stadt Wien in der Zeit zwischen fünf Uhr morgens und acht Uhr abends (mit dem 24. November 1848)

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Welsch (Projektbearbeiter): Bericht über den erfolgreichen Widerstand der badisch-pfälzischen Revolutionsarmee, der im Kampf gegen die aus Richtung Westen und Norden anrückenden Bundestruppen die Einnahme von Käfertal und Ladenburg gelingt. "... angesichts der numerischen Überlegenheit des Feindes [war jedoch] die Neckarlinie auf Dauer nicht zu halten ..." [1848/49: Rev. d. dt. Demokraten in Baden; Baden-Baden 1998, S. 372]

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Welsch (Projektbearbeiter): Gedicht des Schauspielers und Nationalgardisten Heinrich Strampfer auf die Märzrevolution

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Emanuel Kirschner

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Bertha von Suttner

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Leopold Kahn

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Louis Fraenkel

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In many organisms, polarity of the oocyte is established post-transcriptionally via subcellular RNA localization. Many RNAs are localized during oogenesis in Xenopus laevis, including Xlsirts ( Xenopus laevis short interspersed repeat transcripts) [Kloc, 1993]. Xlsirts constitute a large family defined by highly homologous repeat units 79–81 nucleotides in length. Endogenous Xlsirt RNAs use the METRO (Message Transport Organizer) pathway of localization, where RNAs are transported from the nucleus to the mitochondrial cloud in stage I oocytes. Secondly, RNAs anchor at the vegetal pole in stage II oocytes. Exogenous Xlsirt RNAs can also utilize the Late pathway of localization, which involves localization to the vegetal cortex during stage III of oogenesis and results in RNAs anchored in the cortex of the entire vegetal hemisphere. ^ The Xlsirts localization signal is contained within the repeat region. This study was designed to test the hypothesis that there are cis -acting localization elements in Xlsirts, and that higher order structure plays a role. Results of experiments on Xlsirt P11, a 1700 basepair (bp) family member, led to the conclusion that a 137-bp fragment of the repetitive region is necessary and sufficient for METRO and Late pathway localization. This analysis definitively demonstrates that the Xlsirt localization signal for the METRO and Late pathways reside within the repetitive region and not within the flanking regions. Analysis of Xlsirt linker scanning mutations revealed two METRO-pathway specific subelements, and one Late-pathway specific subelement. Functional, computer, and biochemical evidence relates the higher order structure of this element to its ability to function as a localization element. ^ Xlsirt 137 is 99% identical to the Xlsirt consensus sequence identified in this study, suggesting that it is the localization element for all localized Xlsirt family members. The repeat unit was reframed based on function, rather than arbitrarily based on sequence. This work supports the hypothesis presented in 1981 by George Spohr, who originally isolated the Xlsirts, which stated that the highly conserved repetitive elements must be constrained from variability due to some unknown function of the repeats themselves. These studies shed light on the mechanism of RNA localization, linking structure and function. ^