Course of lectures on the physiology and pathology of the central nervous system : delivered at the Royal college of surgeons of England in May, 1858 /

Includes bibliographical references and index.

Animal education; an experimental study on the psychical development of the white rat, correlated with the growth of its nervous system,

Mode of access: Internet.

The nervous system: an elementary handbook of the anatomy and physiology of the nervous system for the use of students of psychology and neurology,

Mode of access: Internet.

Railway injuries: with special reference to those of the back and nervous system, in their medico-legal and clinical aspects. ...

"Reprinted from Wood's medical and surgical monographs."

A treatise on the diseases of the nervous system /

Includes bibliographical references and index.

The nervous system and its diseases. A practical treatise on neurology for the use of physicians and students.

Bibliographic index: p. 1013-1032.

Atlas of the nervous system, including an epitome of the anatomy, pathology, and treatment,

The plates are accompanied by descriptive letter-press on separate leaves. Some of the plates have also outline diagram.

The applied anatomy of the nervous system, being a study of this portion of the human body from a standpoint of its general interest and practical utility,

Mode of access: Internet.

The applied anatomy of the nervous system;

Mode of access: Internet.

The involuntary nervous system,

Bibliography: p. 161-171.

The diseases of the nervous system,

Mode of access: Internet.

Diarrhæa and cholera : their origin, proximate cause, and cure, through the agency of the nervous system by means of ice /

Publisher's press listings.

The threat of predictable and unpredictable pain: Differential effects on central nervous system processing?

Central nervous system performance is disrupted by pain and by the threat of pain. It is not known whether disruption caused by the threat of pain is dependent on the likelihood of pain occurring. We hypothesised that when a painful stimulus is possible but unpredictable central nervous system performance is reduced, but when the pain is predictable and unavoidable it is not. Sixteen healthy subjects performed a reaction time task during predictable and unpredictable conditions (100% and 50% probability of pain, respectively). Group data showed increased reaction time with the threat of pain by 50 ms (95% Cl 16 to 83 ms) for the predictable condition and 46 ms (95% CI 12 to 80 ms) for the unpredictable condition (p < 0.01 for both), but there was no difference between predictable and unpredictable conditions (p = 0.41). However, individual data showed that there was a differential effect in 75% of subjects (p < 0.05 for all) and that there was a greater effect of predictable pain for some subjects and a greater effect of unpredictable pain for others. Reaction time was related to reported anxiety (r = 0.49, p = 0.02 for both conditions). The predictability of a painful stimulus may have a differential effect on central nervous system performance within individuals, but anxiety about the impending pain appears to be important in determining this effect.

A critical role for the parabrachial nucleus in generating central nervous system responses elicited by a systemic immune challenge

Using Fos immunolabelling as a marker of neuronal activation, we investigated the role of the parabrachial nucleus in generating central neuronal responses to the systemic administration of the proinflarnmatory cytokine interleukin-1beta (1 mug/kg, i.a.). Relative to intact animals, parabrachial nucleus lesions significantly reduced the number of Fos-positive cells observed in the central amygdala (CeA), the bed nucleus of the stria terminalis (BNST), and the ventrolateral medulla (VLM) after systemic interleukin-1beta. In a subsequent experiment in which animals received parabrachial-directed deposits of a retrograde tracer, it was found that many neurons located in the nucleus tractus solitarius (NTS) and the VLM neurons were both retrogradely labelled and Fos-positive after interleukin-1beta administration. These results suggest that the parabrachial nucleus plays a critical role in interleukin-1beta-induced Fos expression in CeA, BNST and VLM neurons and that neurons of the NTS and VLM may serve to trigger or at least influence changes in parabrachial nucleus activity that follows systemic interleukin-1beta administration. (C) 2004 Elsevier B.V. All rights reserved.