382 resultados para 2023
Resumo:
O ensino de Administração no Brasil, assim como em outros países, teve início para atender à demanda por profissionais capacitados a responder a necessidade de organização das grandes empresas que estavam em processo de surgimento. Três grandes eixos sustentam o direcionamento desses cursos, ainda nos dias de hoje: econômico, político e educacional. A proposta do presente trabalho é a da reavaliação do paradigma que determinou a construção dos programas das Instituições de Ensino Superior da área de Administração, considerando-se que em tempos atuais, a estrutura sócio-econômica que demanda jovens e adultos formados por esses cursos, configura-se diferentemente daquela que motivou seu surgimento. Naquela época, tendo como inspiração as universidades norte-americanas, as IES brasileiras também visavam atender à demanda das grandes empresas aqui instaladas dentro do processo desenvolvimentista iniciado no governo Vargas. Atualmente, essas grandes empresas, tendo como foco a inovação tecnológica, não mas absorvem adequadamente os profissionais. Novas estruturas organizacionais como aquelas relacionadas com as Economias Solidárias, surgem como possibilidades para os estudantes.(AU)
Resumo:
Acknowledgments This study was funded by the Research Council of Norway (POLARPROG grant 216051; SFF-III grant 223257/ F50) and Svalbard Environmental Protection Fund (SMF grant 13/74). We thank Mathilde Le Moullec for helping with the fieldwork and the Norwegian Meteorological Institute for access to weather data.
Resumo:
Pathogenic mutations in presenilin 1 (PS1) are associated with ≈50% of early-onset familial Alzheimer disease. PS1 is endoproteolytically cleaved to yield a 30-kDa N-terminal fragment (NTF) and an 18-kDa C-terminal fragment (CTF). Using COS7 cells transfected with human PS1, we have found that phorbol 12,13-dibutyrate and forskolin increase the state of phosphorylation of serine residues of the human CTF. Phosphorylation of the human CTF resulted in a shift in electrophoretic mobility from a single major species of 18 kDa to a doublet of 20–23 kDa. This mobility shift was also observed with human PS1 that had been transfected into mouse neuroblastoma (N2a) cells. Treatment of the phosphorylated CTF doublet with phage λ protein phosphatase eliminated the 20- to 23-kDa doublet while enhancing the 18-kDa species, consistent with the interpretation that the electrophoretic mobility shift was due to the addition of phosphate to the 18-kDa species. The NTF and CTF eluted from a gel filtration column at an estimated mass of over 100 kDa, suggesting that these fragments exist as an oligomerized species. Upon phosphorylation of the PS1 CTF, the apparent mass of the NTF- or CTF-containing oligomers was unchanged. Thus, the association of PS1 fragments may be maintained during cycles of phosphorylation/dephosphorylation of the PS1 CTF.
Resumo:
No Brasil, cerca de dois terços da capacidade total instalada de geração de energia elétrica e, em média nos últimos quinze anos, aproximadamente 90% da geração efetiva provêm das hidrelétricas. Este sistema inclui 170 usinas hidrelétricas de médio e grande porte existentes ou previstas até 2023, aproximadamente dois terços delas com capacidade de regularizar vazões e todas operando de maneira interligada. Restrições ambientais, técnicas, sociais e econômicas tem dificultado cada vez mais a implantação de empreendimentos hidráulicos contendo reservatórios de grande porte, tornando a maioria dos novos empreendimentos a fio d´água. Para compreender melhor o processo, este trabalho apresenta um levantamento da evolução anual da capacidade instalada e de armazenamento do sistema desde 1950 até a expansão prevista nos próximos 8 anos, em 2023. Os dados da década de 2000 e a previsão até 2023 de forma ainda mais acentuada indicam uma redução continua e significativa da capacidade relativa de regularização, com impacto direto nas decisões de operação e de expansão do sistema térmico complementar. A fim de avaliar as possíveis consequências da redução da capacidade de regularização, simulações foram realizadas no modelo HIDROTERM (ZAMBON et al. 2012); os resultados apontam para uma necessidade de ser complementar continuamente a energia hídrica, não só em períodos hidrologicamente desfavoráveis.
Resumo:
This study explored children’s experiences of instructional alignment from prekindergarten to kindergarten and analyzed the impact of those alignment experiences on children’s school readiness outcomes. The study answered the following overarching research question: Does the alignment of children’s learning experiences between prekindergarten and kindergarten impact school readiness outcomes? Three sub-questions drove the research design: (1) How do children’s prekindergarten and kindergarten learning experiences align; (2) To what extent does the alignment of early learning experiences predict children’s school readiness outcomes; and (3) Does the quality of prekindergarten classroom teacher interactions moderate the impact of any PK-K alignment effects? Using cluster analysis and hierarchical linear modeling (HLM) to analyze data from over 1,300 children in the 2009 Head Start Family and Child Experiences Survey (FACES), the study found that children have distinct and definable experiences of PK-K alignment. Results also indicated a disparity in children’s PK-K alignment experiences, with Hispanic/Latino children more likely to attend Head Start programs with poor systems transition practices followed by kindergartens with poor classroom structures. The study found that growth in the use of instructional activity centers from prekindergarten to kindergarten is predictive of better literacy and math outcomes. Findings further suggested that boys, minority students, and children from lower income households are predicted to score lower than girls, white classmates, and higher-income peers across school readiness measures. Findings support the need for equitable transition and alignment practices for children from all racial and ethnic groups. They also argue for an increase in child-directed activity centers in kindergarten. With one exception, the current findings did not support the hypothesis that prekindergarten teacher quality is a moderator of alignment effects on children’s school readiness outcomes. The study presents suggestions for further research.
Resumo:
Since the conservative Justice and Development Party (AKP) took power in Turkey in 2002, it has enjoyed a constant winning streak: it won each election (with a support level of 49.83% in 2011), subordinated the army (which had de facto stood above the civilian government) and was reforming the country. The situation in the country was stable (especially when compared to the crises and restlessness in the 1990s), the economy was booming, Turkey’s position in regional politics was strengthening, and Ankara’s significance on the international arena was growing. This encouraged the ruling class to make long-term plans, leading up to the hundredth anniversary of the republic in 2023. In the coming decade, Turkey governed by the AKP was to become one of the global economic and political centres, a full member of the EU and at the same time a political and economic leader in the Middle East. However, the negative trends in the situation both domestically (mass public protests, the deadlocked Kurdish issue and the unsuccessful attempt to amend the constitution) and abroad (the war in Syria and the coup in Egypt) seen over the past few months have laid bare the limitations of the AKP’s rule and have affected the government’s democratic mandate, prestige and credibility on the international arena, as well as peace and order and domestic security. When compared to the beginning of 2013, the way the situation will develop in Turkey is at this moment definitely less predictable; and the possible scenarios include both relative peace (however, with socio-political tension present in the background) and the threat of destabilisation. Therefore, although the AKP will still remain the sole major political force, this party will have to face challenges which will decide not only its political future but also the directions the country will be developing in. However, a comprehensive solution of the accumulated problems and a simple return to the status quo ante, convenient to the government, seem unlikely in the foreseeable future.
Resumo:
The Single Resolution Board (SRB) will be responsible for the resolution of banks in the euro area from 1 January 2016. However, the resources of the Single Resolution Fund (SRF) at the disposal of the SRB will only gradually be built up until 2023. This paper provides estimates of the potential financing needs of the SRF, based on the euro area bank resolutions that actually occurred between 2007 and 2014. We find that the SRF would have been asked to put a total amount of about €72 billion into these failing banks, which is more than the target for the SRF (€55 billion) but less than the amount the SRF could draw on, if the ex-post levies are also taken into account. As this sum would have been required over eight years, the broad conclusion is that bridge financing, in addition to the existing alternative funding, would only have been needed in the early years of the transition.