1000 resultados para 1995_04011630 CTD-62 4502403
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ES-62 is a phosphorylcholine-containing glycoprotein secreted by filarial nematodes. This molecule has been shown to reduce the severity of inflammation in collagen-induced arthritis (CIA) in mice, a model of rheumatoid arthritis, via down-regulation of anti-collagen type 1 immune responses. Malaria parasites induce a pro-inflammatory host immune response and many of the symptoms of malaria are immune system-mediated. Therefore we have asked whether the immunomodulatory properties of ES-62 can down-regulate the severity of malaria infection in BALB/c mice infected with Plasmodium chabaudi. We have found that ES-62 has no significant effect on the course of P. chabaudi parasitaemia, and does not significantly affect any of the measures of malaria-induced pathology taken throughout infection.
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Articles include: Beatrice Heuser: ‘Stalin as Hitler's Successor: Western Interpretations of the Soviet threat', pp. 17-40
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Contiene resumenes bibliograficos de documentos sobre poblacion y temas relacionados que se producen en America Latina y el Caribe, publicados entre 1978-1981.
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Documento en inglés ingresado en Biblioteca (88615)
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Includes bibliography
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Incluye Bibliografía
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Incluye Bibliografía
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V. 2 : Transportes