Expressão dos genes MDR-1, TP53, BCL-2 e BAX em tumor venéreo transmissível canino e sua relação com a agressividade e resposta à terapia

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Association between post-orthodontic treatment gingival margin alterations and symphysis dimensions

Orthodontic therapy is known to be associated with the development of gingival recession. Several factors may be involved in the causal chain of this outcome, including anatomical and behavioral aspects. Among the anatomical aspects, the dimensions of the mandibular symphysis could play a predisposing role. This study evaluated the relationship between the mandibular symphysis dimensions prior to orthodontic therapy and the development of gingival recessions on the lower incisors and cuspids. Records from 189 orthodontically treated adolescents were evaluated, including radiographs, casts and intra-oral photographs. Symphysis dimensions were assessed by cephalograms. Gingival margin alterations were determined in photographs and cast models. Association between gingival margin alterations and symphysis dimensions was tested by chi-square (α=0.05). Occurrence of gingival recession increased after orthodontic therapy. No association was observed on average of symphysis dimensions and the occurrence of gingival recessions. It may be concluded that pretreatment symphysis dimensions may not be used as predictors of gingival recession after orthodontic therapy.

Avaliação das dimensões e relacionamento dos arcos dentários após tratamento com Bionator de Balters

The deficiency of data in the literature took us to evaluate the Bionator of Balters appliance in the alterations of the dimensions and the relationship of the dental archs in children with malocclusion Class II, division 1 of Angle. The experimental group was constituted by 36 pairs cast Caucasians patients, aged between 7 years and 10 months - 11 years and 8 months, being 10 females and 8 males. The Levene´s test showed statistical evidences of likeness among the groups. Statistical analysis was preceded and showed significant alterations (p < 0,005) in the variable indicatives of maxillary first molars' distance, overjet, upper arch total length, upper arch anterior length, right molar relationship, left molar relationship, right canine relationship and left canine relationship. On the other hand, there wasn't significant alteration related to the lower arch and maxillary intercanines distance. The Balters' Bionator appliance had a favorable effect in the improvement of the correction of the malocclusion in Class II (foremost in molars and canines relationship) and transversal increase of the upper arch, mainly in the posterior area of arch.

Modificação de forma e dimensões dos arcos superior e inferior obtidas em modelos de estudo após expansão rápida da maxila com o aparelho hyrax

The aim of an orthodontic treatment is the achievement of a balanced, esthetic and, most of all, stable, intra and inter arches relationship. A common problem observed in occlusion is posterior crossbite and atresic maxilla. This problem may be treated by slow expansion, rapid expansion or surgically assisted expansion. For the present study cast models of 14 children between 7 and 11 years old were evaluated. There were 7 male and 7 female subjects that presented posterior crossbite and needed rapid maxillary expansion. The Hyrax appliance performed the therapy for correction of this transversal alteration, which is a common possibility in the treatment of this malocclusion. It was observed that the distance between the upper first molars and upper cuspids increased significantly; the length of the upper arch decreased and its perimeter increased significantly. At the lower arch there were no dimensional changes.

Otimização do tracionamento de canino impactado pela técnica do arco segmentado: relato de caso clinico

Upper canines impaction are considered the second most frequent and are associated to important esthetics and functional limitations. Among the treatment strategies described in the literature the most commonly used are the extraction of the primary canines and the surgical exposure followed by orthodontic traction, that requires an adequate interdisciplinary approach. The aim of this case report is to draw the attention of the clinician to the possibility of adapting the segmented arch technique to manage a canine impaction clinical case.

Tratamento cirúrgico de canino incluso em mento: relato de caso

The mandibular and maxillary canines when well positioned in the arch, are important functionally and aesthetically. Although these teeth are frequently malpositioned in the dental arch, their absence of eruption are not common, occuring more frequently with the maxillary canine than the mandibular canine. The canine transmigration is a well-known pre eruptive phenomenon in which the tooth goes thru the facial midline, occurring more frequently in the mandible than in maxila. Females are more susceptible than males and the right side more than the left one. Normally the patients do not show any symptoms, and this condition is observed during radiographic exams to diagnose the late exfoliation of the deciduous canine or for any other purpose. Due to the relationship between impacted canines and pathologic lesions, infection, trauma to the adjacent teeth, pain, ectopic eruption and interference with prosthesis, it´s indicated the surgical extraction of these teeth. The goal of this article is to describe and discuss the surgical treatment of an impacted canine (43) in the chin.

Displasia ectodérmica hipohidrótica: un síndrome de interés para la odontología

Hypohidrotic ectodermal dysplasia (HED) is a rare disease of genetic etiology. The most frequent form is of recessive linked to X-chromosome inheritance with affected male and female carriers. It can occur through autosomal mutations, of the gene EDA1 gene being responsible for the majority of the cases. It is characterized by the triad: hypohidrosis, oligodontia and hypotrichosis. We present two cases of patients with HED in which we observed characteristic signs of this syndrome: delicate skin, sparce hair, eyebrows and eyelashes, periorbital wrinkles, perioral and periorbital hyperpigmentation, prominent lips, in addition the patient in case 2 also present the depressed nasal bridge. We also found decreased salivary and lacrimal secretion and maxillary hypoplasia in both cases. At the oral examination in case 1 the upper right and left deciduous canines and lower right deciduous canine were present, and in case 2 the upper and lower (right and left) deciduous canines and two upper (one right and other left) permanent incisors were present with altered morphology, all of these dental elements were healthy. The early dental treatment of patients with HED, especially in the presence of oligodontia, as observed in our cases, is important not only to provide a better quality of life for these patients in the short term, but also an attempt to minimize the changes in facial growth to which these patients are subject.

Influência da reinstrumentação do degrau apical radicular após o posicionamento primário do cone principal de guta-percha noselamento apical

The aim of this study was to evaluate in vitro the apical leakage after the apical re-preparation and replacement of the principal gutta-percha point plus endodontic sealer (Sealer 26TM). Sixty extracted human canines were prepared by using a step back technique up to size 50 K type file apically. At each change of instrument the canals were irrigated with distilled water. After that step, the external surface roots were coated and subdivided into six groups with ten roots each: I – single gutta percha point technique; II – lateral condensation and III – hybrid technique. The IV, V and VI groups were similar to others groups but after to place the principal gutta percha point, it was removed, re-prepared up to size 60K file and in sequence replaced the principal gutta percha point and the root canal filling finished. The specimens were immersed in 2% Rhodamine BTM for 7 days at 37 oC. The apical leakage was measured by Image ToolsTM program. With Kruskal Wallis test statistical analysis showed that there was no significant difference between the techniques (p > 0.05).

Estimativa da altura por dimensões dentárias: uma revisão da literatura

The knowledge of Forensic Anthropology is very importance in cases of identification of human remains. One phase of this process is the study of human height, which can be accomplished with relative ease when intact corpses, complete skeletons or long bones are available. However, the experience of Forensic Dentistry is essential in situations in which there is only information of the skull or of the teeth. The objective of this study was to review in the literature and evaluate works concerning the estimate of the height calculated from dental dimensions. Carrea, in 1920, proposed the estimation of the probable height of an individual by developing formulas for maximum and minimum heights from measurements of the lower central and lateral incisors and canines. The method was used in the case "Josef Mengele", to complement estimates. Tested in the Brazilian population, 70% of match between the actual and the estimated stature were obtained. Using more precise instruments, in the modified method, 96% of correct matching were verified. Recently, a new formula was introduced to estimate height, from measurements of upper teeth, because the technique cannot be used when jaw is not available. The correlation between height and dental dimensions is demonstrated. However, there is still a lack in scientific literature in this field, and further studies are necessary. The estimate of height from dental dimensions can be very useful and important, especially in situations where the complete skeleton it not found, and long bones are not available.

Cisto dentígero: modalidades de tratamento

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Surgical time and complications of total transvaginal (total-NOTES), single-port laparoscopic-assisted and conventional ovariohysterectomy in bitches

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Doppler and Elastography as complementary diagnostic methods for mammary neoplasms in female cats

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Disposição construtiva aplicada em contenção ortodôntica

Disposição construtiva aplicada em contenção ortodôntica. Patente de modelo de utilidade para uma disposição construtiva aplicada em contenção ortodôntica, compreendida por ser do tipo 3x3, com encaixe do tipo "macho-fêmea", sendo que na base da "fêmea" (1) são procedidas retenções (2) mecânicas para fixação por meio de colagem na face lingual dos caninos (3) inferiores, com resina composta, de modo que no interior da "fêmea" (1) é provido um orifício (4) para o encaixe do "macho" (5) e, no centro da cavidade é provido um anel (6) elástico que se encaixa precisamente numa canaleta feita no pino (7) de encaixe do "macho" (5), sendo que, na extremidade dos "machos" (5) podem existir prolongamentos (8) metálicos para retenção de acrílico (9) ou então meios de encaixe para soldagem de um fio metálico (10) espesso, que contorna a face lingual dos dentes (11); inferiores anteriores, de modo que, quando se optar pela retenção em acrilico (9), um fio metálico (10) mais delgado é soldado no terminal de encaixe do "macho" (5) e logo após, o fio (10) e o terminal são recobertos por acrilico (9), sendo que os "machos" (5) poderão ter angulações nos braços (12) de encaixes.

Interação de fibroblastos associados ao câncer em co-cultura com linguagens tumorias mamárias e a resposta terapêutica em o uso da melatonina

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Tumor mamário canino: estudo in vitro, imunomarcação e ação da doxorrubicina

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)