997 resultados para Vias metabólicas


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Nasal fractures are extremely frequent. The nasal bones are the third most frequently fractured bones in the human skeleton. This is due to their prominent position on the face and to the diminished bone thickness. As a result, weak forces can cause nasal fractures, while stronger forces can comminute the nasal bones. In general, assaults, falls and sports injuries are the etiologies most commonly involved in nasal trauma. The diagnosis of such fractures is basically clinical and their treatment is usually by closed reduction with good results reported in all the relevant literature. Thus, the aim of this paper is to report a modification of the closed reduction technique for the treatment of these fractures.

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This essay analyzes the manifestations of the idealism of romantic orientation in the poetry of Augusto dos Anjos and Pedro Kilkerry, showing the points of contact between their oeuvres and demonstrating that many of the innovative aesthetic procedures of their poetry appear as a reaction to urgencies of an idealistic conception of poetry. Augusto dos Anjos and Pedro Kilkerry attest the anxiety of apprehension of connections with a super-sensible sphere in phenomenal reality. Although this takes a different form in each of the poets, it can refer to a common poetic ideal that transcends the concrete reality. To accomplish this, they use aesthetic procedures that modernize the language of the romantic sublime – Augusto dos Anjos uses a hybrid philosophical repertoire that marks his poetry with a tense and innovative prosaic language, and Pedro Kilkerry opts for the indirect representation, made by an evocative and metonymic language, that evidences the mystery of the transcendent ideal without deciphering it.

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Fundamento: A doença coronária tem sido amplamente estudada em pesquisas cardiovasculares. No entanto, pacientes com doença arterial periférica (DAP) têm piores resultados em comparação àqueles com doença arterial coronariana. Portanto, os estudos farmacológicos com artéria femoral são altamente relevantes para a melhor compreensão das respostas clínicas e fisiopatológicas da DAP. Objetivo: Avaliar as propriedades farmacológicas dos agentes contráteis e relaxantes na artéria femoral de ratos. Métodos: As curvas de resposta de concentração à fenilefrina contrátil (FC) e à serotonina (5-HT) e os agentes relaxantes isoproterenol (ISO) e forskolina foram obtidos na artéria femoral de ratos isolada. Para as respostas ao relaxamento, os tecidos foram contraídos com FC ou 5-HT. Resultados: A potência de classificação na artéria femoral foi de 5-HT > FC para as respostas contráteis. Em tecidos contraídos com 5-HT, as respostas de relaxamento ao isoproterenol foram praticamente abolidas em comparação aos tecidos contraídos com FC. A forskolina, um estimulante da adenilil ciclase, restaurou parcialmente a resposta de relaxamento ao ISO em tecidos contraídos com 5-HT. Conclusão: Ocorre uma interação entre as vias de sinalização dos receptores β-adrenérgicos e serotoninérgicos na artéria femoral. Além disso, esta pesquisa fornece um novo modelo para estudar as vias de sinalização serotoninérgicas em condições normais e patológicas que podem ajudar a compreender os resultados clínicos na DAP.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Pós-graduação em Arquitetura e Urbanismo - FAAC

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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This work deals with the continuation of Scientific Initiation research initiated by Tamura (2012), which draws up a mixture of soil and recycled aggregate analysis for paving of low traffic volume roads using local materials from the Vale do Paraíba region. The main steps of the process were the soil and recycled aggregate characterization, along with grading tests and California Bearing Ratio (CBR) applied to the soil, the recycled aggregate and the mixture of soil and recycled aggregate; aiming their use as base and sub-base in paving urban roads. The results are discussed, emphasizing the mechanical behavior. The current results are compared with the results of IC Tamura research, taking decisions over this job to the final product best result. For a greater understanding of the work in general were described paving, its structure, its components and its physical behavior. It has been intended to emphasize the importance of the mixture of soil and recycled aggregate to meet the quality requirements and compliance with the specifications of current technical standards, in the context of durability, natural materials economy, decreases volume in landfills and cost reduction