1000 resultados para Mieloma múltiple, Citogenètica
Resumo:
Background:There is no actual evidence that the ART are directly related to the occurrence of weight discordance. In some studies, ART-‐conceived twin pregnancies are at greater risk than non-‐ART-‐conceived ones for pregnancy complications and adverse perinatal outcome: the incidences of pregnancy-‐induced hypertension, uterine bleeding, premature contractions, IUGR, fetal death, discordance, and cesarean section were significantly higher. Discordance rate was elevated (25.3% vs.17.0%) among ART twins, which can increase perinatal risk (increased incidence of SGA and NICU admission). Other studies say that perinatal and neonatal morbidity, gestational age at delivery, and birth weight are not affected by ART. Regarding the first trimester ultrasound, some studies didn’t notice significant differences in CRL disparity or birth weight discordance between spontaneous and ART-‐ conceived dichorionic twin pregnancies. In ART-‐conceived dichorionic twin pregnancies, CRL disparity may be associated with birth weight discordance. In some studies, CRL discordance in twin pregnancies in the first trimester was a frequent finding. Objectives: To analyze the association of the ART in the occurrence of weight discordance in the pregnancies between 2010 and 2013 in the Hospital Universitari de Girona Doctor Josep Trueta, and to describe the proportion of diagnosis of growth discordance in the first trimester by the ultrasonography technology. Methods: A retrospective cohort study will be performed in those patients with twin pregnancies between 2010 and 2013, within the Hospital Universitari de Girona Doctor Josep Trueta (HUJT). A retrospective and descriptive study will be done in those cases with discordance weight in the moment of the birth, in which the CRL will be studied in the first trimester ultrasound, describing the percentage of discordance detected in that moment. The general characteristics of the sample are going to be analyzed by Logistic RegressionInfluenceof
Resumo:
Background:There is no actual evidence that the ART are directly related to the occurrence of weight discordance. In some studies, ART-‐conceived twin pregnancies are at greater risk than non-‐ART-‐conceived ones for pregnancy complications and adverse perinatal outcome: the incidences of pregnancy-‐induced hypertension, uterine bleeding, premature contractions, IUGR, fetal death, discordance, and cesarean section were significantly higher. Discordance rate was elevated (25.3% vs.17.0%) among ART twins, which can increase perinatal risk (increased incidence of SGA and NICU admission). Other studies say that perinatal and neonatal morbidity, gestational age at delivery, and birth weight are not affected by ART. Regarding the first trimester ultrasound, some studies didn’t notice significant differences in CRL disparity or birth weight discordance between spontaneous and ART-‐ conceived dichorionic twin pregnancies. In ART-‐conceived dichorionic twin pregnancies, CRL disparity may be associated with birth weight discordance. In some studies, CRL discordance in twin pregnancies in the first trimester was a frequent finding. Objectives: To analyze the association of the ART in the occurrence of weight discordance in the pregnancies between 2010 and 2013 in the Hospital Universitari de Girona Doctor Josep Trueta, and to describe the proportion of diagnosis of growth discordance in the first trimester by the ultrasonography technology. Methods: A retrospective cohort study will be performed in those patients with twin pregnancies between 2010 and 2013, within the Hospital Universitari de Girona Doctor Josep Trueta (HUJT). A retrospective and descriptive study will be done in those cases with discordance weight in the moment of the birth, in which the CRL will be studied in the first trimester ultrasound, describing the percentage of discordance detected in that moment. The general characteristics of the sample are going to be analyzed by Logistic RegressionInfluenceof
Resumo:
About 85% of multiple sclerosis (MS) cases start as clinically isolated syndrome (CIS).When patients present with a CIS, clinicians face with many questions, most of themrelated with prognosis and treatment. Thereby, patients with CIS have been focus ofresearch. Several studies have demonstrated a relationship between positive IgM lipidspecific oligoclonal band pattern in CSF and higher lesion load on MRI brain scan, higher number of relapses and greater disability, even at the first stages of the disease. On the other hand, no studies have used this previous evidence to treat with more aggressive disease modifying therapy in initial stages of disease course to prevent the earlier axonal damage. The aim of this study is to assess the most effective approved treatment for MS and current therapy for CIS patients presenting high risk to develop CDMS and with biomarkers of poor prognosis. Among this group of patients any disease activity will eventually lead to disability. Therefore, the earlier the treatment is initiated, the more effective to prevent disability will be. It is considered that “time lost is brain lost” and since once damage is established, there is no therapy to be regained later on. In this phase III clinical trial, 172 patients will be randomized 1:1 to receive Interferon β-1b or natalizumab over 96 weeks. Time to develop clinical definitive multiple sclerosis (CDMS) will be included as primary endpoint. Other secondary endpoints will include clinical data, magnetic resonance imaging (MRI) measurements and quality of life tests
Resumo:
Aquest qüestionari pretén valorar la teva experiència en la participació del projecte que desenvolupes en la universitat. El qüestionari és anònim i no trigaràs més de 15 minuts en respondre'l.
Resumo:
Aquest qüestionari pretén valorar l’experiència dels estudiants dins del projecte d’Aprenentatge i Servei que promous. El qüestionari és confidencial i no trigaràs més de 15 minuts en respondre'l.
Resumo:
Aquest qüestionari pretén valorar l’experiència dels estudiants dins del projecte d’Aprenentatge i Servei que promous. El qüestionari és confidencial i no trigaràs més de 15 minuts en respondre'l.
Resumo:
Aquest qüestionari pretén valorar la teva experiència en la participació del projecte que desenvolupes en la universitat. El qüestionari és anònim i no trigaràs més de 15 minuts en respondre'l.
Resumo:
Aquest qüestionari pretén valorar la teva experiència en la participació del projecte que desenvolupes en la universitat. El qüestionari és anònim i no trigaràs més de 15 minuts en respondre'l.
Resumo:
Aquest qüestionari pretén valorar l’experiència dels estudiants dins del projecte d’Aprenentatge i Servei que promous. El qüestionari és confidencial i no trigaràs més de 15 minuts en respondre'l.
Resumo:
Aquest qüestionari pretén valorar la teva experiència en la participació del projecte que desenvolupes en la universitat. El qüestionari és anònim i no trigaràs més de 15 minuts en respondre'l.
Resumo:
Aquest qüestionari pretén valorar l’experiència dels estudiants dins del projecte d’Aprenentatge i Servei que promous. El qüestionari és confidencial i no trigaràs més de 15 minuts en respondre'l.
Resumo:
Aquest qüestionari pretén valorar l’experiència dels estudiants dins del projecte d’Aprenentatge i Servei que promous. El qüestionari és confidencial i no trigaràs més de 15 minuts en respondre'l.
Resumo:
Aquest qüestionari pretén valorar l’experiència dels estudiants dins del projecte d’Aprenentatge i Servei que promous. El qüestionari és confidencial i no trigaràs més de 15 minuts en respondre'l.
Resumo:
Aquest qüestionari pretén valorar l’experiència dels estudiants dins del projecte d’Aprenentatge i Servei que promous. El qüestionari és confidencial i no trigaràs més de 15 minuts en respondre'l.
Resumo:
Aquest qüestionari pretén valorar l’experiència dels estudiants dins del projecte d’Aprenentatge i Servei que promous. El qüestionari és confidencial i no trigaràs més de 15 minuts en respondre'l.
