Experiência da Rede Brasileira de Teleodontologia

Este artigo descreve a experiência da Rede Brasileira de Teleodontologia como parte das estratégias em eHealth. Várias instituições de todo o país participam ou vêm recebendo treinamento e suporte para a implantação de seus próprios núcleos de Telessaúde e Teleodontologia. Diversas iniciativas estão sendo tomadas de modo articulado, a fim de facilitar a criação e a consolidação de uma rede colaborativa de trabalho em Telessaúde e Teleodontologia

Software livre e licenças públicas [direitos autorais]

Apresenta os conceitos de licenças públicas e software livre. Vídeo da atividade 2, unidade 2, do Curso de Direitos Autorais, ofertado pela Universidade Aberta do SUS.

Selection And Validation Of Reference Genes For Functional Studies In The Calliphoridae Family.

The genera Cochliomyia and Chrysomya contain both obligate and saprophagous flies, which allows the comparison of different feeding habits between closely related species. Among the different strategies for comparing these habits is the use of qPCR to investigate the expression levels of candidate genes involved in feeding behavior. To ensure an accurate measure of the levels of gene expression, it is necessary to normalize the amount of the target gene with the amount of a reference gene having a stable expression across the compared species. Since there is no universal gene that can be used as a reference in functional studies, candidate genes for qPCR data normalization were selected and validated in three Calliphoridae (Diptera) species, Cochliomyia hominivorax Coquerel, Cochliomyia macellaria Fabricius, and Chrysomya albiceps Wiedemann . The expression stability of six genes ( Actin, Gapdh, Rp49, Rps17, α -tubulin, and GstD1) was evaluated among species within the same life stage and between life stages within each species. The expression levels of Actin, Gapdh, and Rp49 were the most stable among the selected genes. These genes can be used as reliable reference genes for functional studies in Calliphoridae using similar experimental settings.

Elevated Risk for HIV-1 Infection in Adolescents and Young Adults in São Paulo, Brazil

Background. Recent studies have sought to describe HIV infection and transmission characteristics around the world. Identification of early HIV-1 infection is essential to proper surveillance and description of regional transmission trends. In this study we compare people recently infected (RI) with HIV-1, as defined by Serologic Testing Algorithm for Recent HIV Seroconversion (STARHS), to those with chronic infection. Methodology/Principal Findings Subjects were identified from 2002-2004 at four testing sites in São Paulo. Of 485 HIV-1-positive subjects, 57 (12%) were defined as RI. Of the participants, 165 (34.0%) were aware of their serostatus at the time of HIV-1 testing. This proportion was statistically larger (p<0.001) among the individuals without recent infection (n = 158, 95.8%) compared to 7 individuals (4.2%) with recently acquired HIV-1 infection. In the univariate analysis, RI was more frequent in <25 and >59 years-old age strata (p<0.001). The majority of study participants were male (78.4%), 25 to 45 years-old (65.8%), white (63.2%), single (61.7%), with family income of four or more times the minimum wage (41.0%), but with an equally distributed educational level. Of those individuals infected with HIV-1, the predominant route of infection was sexual contact (89.4%), with both hetero (47.5%) and homosexual (34.5%) exposure. Regarding sexual activity in these individuals, 43.9% reported possible HIV-1 exposure through a seropositive partner, and 49.4% reported multiple partners, with 47% having 2 to 10 partners and 37.4% 11 or more; 53.4% of infected individuals reported condom use sometimes; 34.2% reported non-injecting, recreational drug use and 23.6% were reactive for syphilis by VDRL. Subjects younger than 25 years of age were most vulnerable according to the multivariate analysis. ) Conclusions/Significance In this study, we evaluated RI individuals and discovered that HIV-1 has been spreading among younger individuals in São Paulo and preventive approaches should, therefore, target this age stratum

Dynamical models for computer viruses propagation

Nowadays, digital computer systems and networks are the main engineering tools, being used in planning, design, operation, and control of all sizes of building, transportation, machinery, business, and life maintaining devices. Consequently, computer viruses became one of the most important sources of uncertainty, contributing to decrease the reliability of vital activities. A lot of antivirus programs have been developed, but they are limited to detecting and removing infections, based on previous knowledge of the virus code. In spite of having good adaptation capability, these programs work just as vaccines against diseases and are not able to prevent new infections based on the network state. Here, a trial on modeling computer viruses propagation dynamics relates it to other notable events occurring in the network permitting to establish preventive policies in the network management. Data from three different viruses are collected in the Internet and two different identification techniques, autoregressive and Fourier analyses, are applied showing that it is possible to forecast the dynamics of a new virus propagation by using the data collected from other viruses that formerly infected the network. Copyright (c) 2008 J. R. C. Piqueira and F. B. Cesar. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Lack of Antilipoprotein Lipase Antibodies in Takayasu's Arteritis

Background. Antilipoprotein lipase (anti-LPL) antibodies were described in rheumatic diseases. In systemic lupus erythematosus they were highly associated with inflammatory markers and dyslipidemia, and may ultimately contribute to vascular damage. The relevance of this association in Takayasu's arteritis, which is characterized by major inflammatory process affecting vessels, has not been determined. Objectives. To analyze the presence of anti-LPL antibodies in patients with Takayasu's arteritis and its association with inflammatory markers and lipoprotein risk levels. Methods. Thirty sera from patients with Takayasu's arteritis, according to ACR criteria, were consecutively included. IgG anti-LPL was detected by a standard ELISA. Lipoprotein risk levels were evaluated according to NCEP/ATPIII. Inflammatory markers included ESR and CRP values. Results. Takayasu's arteritis patients had a mean age of 34 years old and all were females. Half of the patients presented high ESR and 60% elevated CRP. Lipoprotein NCEP risk levels were observed in approximately half of the patients: 53% for total cholesterol, 43% for triglycerides, 16% for HDL-c and 47% for LDL-c. In spite of the high frequency of dyslipidemia and inflammatory markers in these patients no anti-LPL were detected. Conclusions. The lack of anti-LPL antibodies in Takayasu's disease implies distinct mechanisms underlying dyslipidemia compared to systemic lupus erythematosus. Copyright (C) 2009 Jozelio Freire de Carvalho et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Afferent Connections to the Rostrolateral Part of the Periaqueductal Gray: A Critical Region Influencing the Motivation Drive to Hunt and Forage

Previous studies have shown that a particular site in the periaqueductal gray (PAG), the rostrolateral PAG, influences the motivation drive to forage or hunt. To have a deeper understanding on the putative paths involved in the decision-making process between foraging, hunting, and other behavioral responses, in the present investigation, we carried out a systematic analysis of the neural inputs to the rostrolateral PAG (rlPAG), using Fluorogold as a retrograde tracer. According to the present findings, the rlPAG appears to be importantly driven by medial prefrontal cortical areas involved in controlling attention-related and decision-making processes. Moreover, the rlPAG also receives a wealth of information from different amygdalar, hypothalamic, and brainstem sites related to feeding, drinking, or hunting behavioral responses. Therefore, this unique combination of afferent connections puts the rlPAG in a privileged position to influence the motivation drive to choose whether hunting and foraging would be the most appropriate adaptive responses. Copyright (C) 2009 Sandra Regina Mota-Ortiz et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Boletim eletr??nico de bibliografias especializadas: igualdade de g??nero

A 2?? edi????o de 2013 do Boletim Eletr??nico de Bibliografias Especializadas destaca o tema Igualdade de G??nero. O documento traz indica????es de pu-blica????es do acervo da Biblioteca Graciliano Ramos/ENAP com reflex??es acerca das desi-gualdades entre homens e mulheres e suas consequ??ncias ?? sociedade. O objetivo ?? dar publicidade a esses materiais, visando a con-tribuir para uma melhor compreens??o do com-plexo cen??rio de defini????o das prioridades p??blicas e da formula????o de pol??ticas p??blicas governamentais comprometidas com a pers-pectiva de g??nero, em seus diversos aspectos. De acordo com a Organiza????o das Na????es Unidas para a Educa????o, a Ci??ncia e a Cultura (Unesco), os direitos das mulheres devem ser entendidos como direitos humanos e cultu-rais fundamentais. J?? a Pol??tica Nacional para as Mulheres, coordenada pela Secre-taria Especial de Pol??ticas para as Mulhe-res (SPM), da Presid??ncia da Rep??blica, tem como pressupostos e princ??pios a equi-dade, a autonomia das mulheres, a laicida-de do Estado, a universalidade das pol??ti-cas, a justi??a social, a transpar??ncia dos atos p??blicos, a participa????o e o controle social.

Boletim eletr??nico de bibliografias especializadas: pol??tica energ??tica - setor el??trico

A implementa????o de uma Pol??tica Energ??tica ?? essencial para o desenvolvimento do Pa??s, na medida em que estabelece metas, meios e diretrizes para melhorar a confiabilidade e a qualidade do suprimento energ??tico. Ela define ainda o papel dos diversos agentes e institui????es que atuam na ??rea energ??tica brasileira. A exist??ncia de tal pol??tica ?? condi????o fundamental para garantir o planejamento das atividades energ??ticas, tanto do lado da produ????o quanto do consumo, sem comprometer o meio ambiente e a qualidade de vida das pr??ximas gera????es. Em fun????o da import??ncia da pol??tica energ??tica ao desenvolvimento sustent??vel e ?? melhoria do bemestar da popula????o brasileira, a 1?? edi????o de 2013 do Boletim Eletr??nico de Bibliografias Especializadas destaca o tema Pol??tica Energ??tica - Setor El??trico, com indica????es de publica????es pertencentes ao acervo da Biblioteca Graciliano Ramos/ENAP. O intuito ?? divulgar obras que possam auxiliar gestores, servidores e trabalhadores da ??rea de Energia no Brasil em seus processos decis??rios, assim como obras que tratam da rica hist??ria do setor e seus planos para o futuro.

Boletim eletr??nico de bibliografias especializadas: gest??o de risco

O tema escolhido ?? Gest??o de Risco, que aborda quest??es emergenciais como a identifica????o de fatores cr??ticos para o sucesso da gest??o e a avalia????o de oportunidades em contextos adversos, imprescind??vel ao planejamento e ?? implementa????o de pol??ticas p??blicas.

Boletim eletr??nico de bibliografias especializadas: gest??o de conflito

O assunto ?? de extrema import??ncia para os processos de avalia????o e enfrentamento de situa????es de diverg??ncias de modo a prevenir seus efeitos negativos, bem como extrair os aspectos positivos, buscando, assim, comunica????o e negocia????o de maneira estrat??gica.

Boletim eletr??nico de bibliografias especializadas: gest??o de crise

O terceiro Boletim de Bibliografias Especializadas apresenta o tema ???Gest??o de Crise???, com indica????es de livros e artigos de revistas sobre o tema pertencentes ao acervo da Biblioteca. Essas publica????es mostram que a gest??o de crise ?? uma problem??tica com a qual toda administra????o deve preocupar-se. Afinal, crise ?? um evento imprevis??vel capaz de provocar preju??zos significativos a uma institui????o e, consequentemente, aos seus integrantes. Uma quest??o que se apresenta ??: depois da crise instaurada, como gerenci??-la? O conhecimento das caracter??sticas de uma crise possibilitar?? compreend??-la melhor e facilitar?? o ??rduo esfor??o em gerenci??-la.

Boletim eletr??nico de bibliografias especializadas: inova????o na gest??o p??blica

O 4?? Boletim Eletr??nico de Bibliografias Especializadas destaca o tema ???Inova????o na Gest??o P??blica???, com indica????es de livros e artigos de revistas pertencentes ao acervo da Biblioteca. O intuito ?? divulgar obras que auxiliem servidores p??blicos na transforma????o de processos de trabalho para melhor atender ao cidad??o.

Boletim eletr??nico de bibliografias especializadas:acesso ?? informa????o p??blica

A Lei de Acesso ?? Informa????o (n??12.527/2011) entra em vigor hoje, dia 16 de maio, e traz importantes mudan??as para a administra????o p??blica. A nova legisla????o proporciona, ao cidad??o brasileiro, o acesso amplo ??s informa????es e a documentos p??blicos sob a guarda do Estado. A partir dessa data, todo cidad??o poder??, a qualquer momento, solicitar informa????es diversas, sem necessidade de motiva????o para seu uso, garantindo, assim, o exerc??cio de seu direito constitucional ao acesso ?? informa????o p??blica. A Lei estabelece que o acesso seja a regra e o sigilo, a exce????o. Diante desse cen??rio, o 5?? Boletim Eletr??nico de Bibliografias Especializadas destaca o tema ???Acesso ?? informa????o???, com indica????es de publica????es pertencentes ao acervo da Biblioteca Graciliano Ramos/ENAP. O intuito ?? divulgar obras que auxiliem servidores p??blicos na compreens??o dos princ??pios da nova Lei e na mudan??a da cultura do sigilo, ainda presente na gest??o da informa????o p??blica.

Boletim eletr??nico de bibliografias especializadas:gest??o da informa????o e do conhecimento

O acesso ?? Informa????o proporcionado pela Lei n??12.527/2011, que entrou em vigor dia 16 de maio, pela qual o cidad??o brasileiro teve garantido o seu direito ao acesso amplo ??s informa????es e a documentos p??blicos, tamb??m provocou o incentivo necess??rio para aprofundar a discuss??o de temas importantes, relacionados ?? informa????o p??blica como a gest??o documental, a seguran??a da informa????o, a gest??o da informa????o e a gest??o do conhecimento. Este Boletim tem por objetivo indicar livros e artigos que tratam da tem??tica, e possam auxiliar os servidores p??blicos nesta discuss??o, uma vez que, gerenciar o conhecimento tornou-se uma necessidade e uma responsabilidade da Administra????o P??blica para que ela possa aumentar a efetividade dos servi??os p??blicos e melhorar a sociedade a qual ela serve.