Cerf Berr und seine Zeit : Vortrag, geh. in Straßburg am 17. Jan. 1906

von M. Ginsburger.

Vertebral artery stenosis in the Basilar Artery International Cooperation Study (BASICS): prevalence and outcome

We assessed the prevalence of vertebral artery (VA) stenosis or occlusion and its influence on outcome in patients with acute basilar artery occlusion (BAO). We studied 141 patients with acute BAO enrolled in the Basilar Artery International Cooperation Study (BASICS) registry of whom baseline CT angiography (CTA) of the intracranial VAs was available. In 72 patients an additional CTA of the extracranial VAs was available. Adjusted risk ratios (aRRs) for death and poor outcome, defined as a modified Rankin Scale score ≥4, were calculated with Poisson regression in relation to VA occlusion, VA occlusion or stenosis ≥50 %, and bilateral VA occlusion. Sixty-six of 141 (47 %) patients had uni- or bilateral intracranial VA occlusion or stenosis ≥50 %. Of the 72 patients with intra- and extracranial CTA, 46 (64 %) had uni- or bilateral VA occlusion or stenosis ≥50 % and 9 (12 %) had bilateral VA occlusion. Overall, VA occlusion or stenosis ≥50 % was not associated with the risk of poor outcome. Patients with intra- and extracranial CTA and bilateral VA occlusion had a higher risk of poor outcome than patients without bilateral VA occlusion (aRR, 1.23; 95 % CI 1.02-1.50). The risk of death did not depend on the presence of unilateral or bilateral VA occlusion or stenosis ≥50 %. In conclusion, in patients with acute BAO, unilateral VA occlusion or stenosis ≥50 % is frequent, but not associated with an increased risk of poor outcome or death. Patients with BAO and bilateral VA occlusion have a slightly increased risk of poor outcome.

Nothgedrungene Rechtsbefugte Vorstellung, Beschwehrung und diverses unterthäniges Bitten unser Derer provisionaliter verordneten dreyen Casten-Meistern Contra Beer Löw Isaac und Süßkind Samuel Stern : Ad Decreta de 29. Octobr. 1751 & 7. Jan. und 1. Martii 1752 ; Cum Postscripto

[Jacob Ochs ; Beer Hertz Oppenheimer ; Moyses Benedickt Beyfuß] [[Elektronische Ressource]]

Guarantie-Schein von acht gesessenen Bürgerlichen Deputirten, die Einkünffte der Stadt auff hundert tausend Gülden jährlichen Einkünfften, auff den Fuß, wie sie Magistratus bißher erhebt, gleich in primo anno weiter und hernach viel höher zuverrechnen : In Causa Commissionis Impetrantischer Bürgerschafft der Kayserl. Freyen Reichs- auch Wahl- und Crönungs-Stadt Franckfurth Contra E. E. Rath allda ; Ihro Röm. Kayserl. Majestät benebenst einem allerunterthänigsten Memorial sub lit. B originaliter ... den 28. Jan. 1715 ... überreicht

[David Düring, Peter Bischoff, Johannes Klotz, Johann Conrad Siegling, Paul Hennrici, David Klotz, Joh. Dietrich Notebohm, Joachim Hoppe] [[Elektronische Ressource]]

Die In zehen Jahren zum zweitenmal mit Feuer heimgesuchte Juden-Gaß : da nemlich 1711 den 14. Jan. des Abends um 8 Uhr, biß den andern Tag des Abends, die gantze biß auf den kleinsten Splitter, zu einem Aschen-Hauffen wurde ; In diesem 1721sten Jahr ... entstund abermal eine entsetzliche Feuers-Brunst ...

[I. B. G. ?] [[Elektronische Ressource]]

Low but contrasting neutral genetic differentiation shaped by winter temperature in European great tits

Gene flow is usually thought to reduce genetic divergence and impede local adaptation by homogenising gene pools between populations. However, evidence for local adaptation and phenotypic differentiation in highly mobile species, experiencing high levels of gene flow, is emerging. Assessing population genetic structure at different spatial scales is thus a crucial step towards understanding mechanisms underlying intraspecific differentiation and diversification. Here, we studied the population genetic structure of a highly mobile species – the great tit Parus major – at different spatial scales. We analysed 884 individuals from 30 sites across Europe including 10 close-by sites (< 50 km), using 22 microsatellite markers. Overall we found a low but significant genetic differentiation among sites (FST = 0.008). Genetic differentiation was higher, and genetic diversity lower, in south-western Europe. These regional differences were statistically best explained by winter temperature. Overall, our results suggest that great tits form a single patchy metapopulation across Europe, in which genetic differentiation is independent of geographical distance and gene flow may be regulated by environmental factors via movements related to winter severity. This might have important implications for the evolutionary trajectories of sub-populations, especially in the context of climate change, and calls for future investigations of local differences in costs and benefits of philopatry at large scales.