The influence of mouse Ped gene expression on postnatal development

The Ped (preimplantation embryo development) gene, whose product is Qa-2 protein, is correlated with a faster rate of preimplantation development (Ped fast phenotype) in mice that express Qa-2 protein compared with mice with an absence of Qa-2 protein (Ped slow phenotype). In the current study, we have used two congenic mouse strains differentially expressing the Ped gene, strain B6.K1 (Ped slow; Qa-2 negative) and strain B6.K2 (Ped fast; Qa-2 positive), to investigate the effects of Ped gene expression on postnatal growth profiles, systolic blood pressure and adult organ allometry. At birth, B6.K1 mice were moderately lighter than B6.K2 mice. B6.K1 mice became heavier during postnatal life (P

Die heiligen Schriften der Israeliten : nach dem masoretischen Texte neu übersetzt

von J. Johlson

Das Evangelium Johannis : in neu-griechischer Sprache

C.F. Spittler

Alte aber nunmehro wider neu hervorgegebene Zeitungen : auff den neuen Hochzeit-EhrenTag des ... Herrn, H. Christian Meiers, diser käyserlichen, freyen, Reichs-Ansee und HandelStatt Bremen, fürnehmen Burger und Handelsmans mt der ... Jungffer J. Gebecca Hollen, des ... Herren H. Herman Hollen ... wollverdienten rahtsverwandten hinterlassenen eheleiblichen J. Tochter, als dieselbe den 21. Novembris, des zum neuen lauffenden 1671. Jahres ... glückwunschend gefeyret ward

Zusamen gesuchet und ... übergeben von Inbenanten [Johan Meyer ...]

Identification d'un nouveau gène suppresseur de tumeurs candidat (EphA10) dans les tumeurs mammaires des souris transgéniques MMTV/neu

Thèse numérisée par la Direction des bibliothèques de l'Université de Montréal.

Identification d'un nouveau gène suppresseur de tumeurs candidat (EphA10) dans les tumeurs mammaires des souris transgéniques MMTV/neu

Thèse numérisée par la Direction des bibliothèques de l'Université de Montréal.

The Burkholderia Cenocepacia OmpA-Like Protein BCAL2958: Identification, Characterization, and Detection of Anti-BCAL2958 Antibodies in Serum from B. Cepacia Complex-Infected Cystic Fibrosis Patients

Respiratory infections by bacteria of the Burkholderia cepacia complex (Bcc) remain an important cause of morbidity and mortality among cystic fibrosis patients, highlighting the need for novel therapeutic strategies. In the present work we have studied the B. cenocepacia protein BCAL2958, a member of the OmpA-like family of proteins, demonstrated as highly immunogenic in other pathogens and capable of eliciting strong host immune responses. The encoding gene was cloned and the protein, produced as a 6× His-tagged derivative, was used to produce polyclonal antibodies. Bioinformatics analyses led to the identification of sequences encoding proteins with a similarity higher than 96 % to BCAL2958 in all the publicly available Bcc genomes. Furthermore, using the antibody it was experimentally demonstrated that this protein is produced by all the 12 analyzed strains from 7 Bcc species. In addition, results are also presented showing the presence of anti-BCAL2958 antibodies in sera from cystic fibrosis patients with a clinical record of respiratory infection by Bcc, and the ability of the purified protein to in vitro stimulate neutrophils. The widespread production of the protein by Bcc members, together with its ability to stimulate the immune system and the detection of circulating antibodies in patients with a documented record of Bcc infection strongly suggest that the protein is a potential candidate for usage in preventive therapies of infections by Bcc.

The Diet of Preschool Children in the Mediterranean Countries of the European Union: A Systematic Review

This systematic review discusses data on the dietary intake of preschool children living in the Mediterranean countries of the European Union, including the comparison with a Mediterranean-like diet and the association with nutritional status. Specifically, data from the multinational European Identification and Prevention on Dietary and life style induced health effects in children and infants (IDEFICS) study and national studies, such as the Estudo do Padrão Alimentar e de Crescimento Infantil (EPACI) study and Geração XXI cohort in Portugal, ALimentando la SAlud del MAñana (ALSALMA) study in Spain, Étude des Déterminants pré-et postnatals précoces du développement et de la santé de l'ENfant (EDEN) cohort in France, Nutrintake 636 study in Italy, and Growth, Exercise and Nutrition Epidemiological Study in preSchoolers (GENESIS) cohort in Greece, were analyzed. In the majority of countries, young children consumed fruit and vegetables quite frequently, but also consumed sugared beverages and snacks. High energy and high protein intakes mainly from dairy products were found in the majority of countries. The majority of children also consumed excessive sodium intake. Early high prevalence of overweight and obesity was found, and both early consumption of energy-dense foods and overweight seemed to track across toddler and preschool ages. Most children living in the analyzed countries showed low adherence to a Mediterranean-like diet, which in turn was associated with being overweight/obese. Unhealthier diets were associated with lower maternal educational level and parental unemployment. Programs promoting adherence of young children to the traditional Mediterranean diet should be part of a multi-intervention strategy for the prevention and treatment of pediatric overweight and obesity.

Primary Immunodeficiency Associated with Chromosomal Aberration - an ESID Survey

Patients with syndromic features frequently suffer from recurrent respiratory infections, but little is known about the spectrum of immunological abnormalities associated with their underlying chromosomal aberrations outside the well-known examples of Down and DiGeorge syndromes. Therefore, we performed this retrospective, observational survey study.

Wirtschaftswissen neu verhandeln. Economic Literacy mittels Psychodrama

Economic Literacy ist ein politischer und demokratischer Ansatz. Er entstand in den 1980er Jahren im Kontext der Internationalen Frauenbewegung. Angelehnt an die Pädagogik der Befreiung von Paulo Freire, soll dabei Wirtschaftswissen in gemeinschaftlicher Auseinandersetzung gestaltet und veränderbar gemacht werden. Die beiden Autorinnen stellen in diesem Beitrag ihre Bildungsarbeit vor. Sie plädieren in der Tradition eines feministisch inspirierten Hinterfragens neoliberaler Konzepte für ein Wirtschaftswissen, das die Lebensdienlichkeit der Ökonomie ins Zentrum stellt. Mittels der Methode des Psychodramas suchen sie Antwort auf Fragen wie: Wem wird die Kompetenz (nicht) zugeschrieben, über Wirtschaft zu sprechen? Welche AkteurInnen mit welchen Interessen bekommen den Raum, ihre wirtschaftlichen Positionen kundzutun? Wer hält die Deutungsmacht über das "richtige" Wirtschaftswissen, wer die Macht zu entscheiden? Wirtschaftswissen soll so neu verhandelt werden, die Wirtschaftsexpertise von Frauen sichtbar gemacht und letztlich die Frage virulent werden: Wie wollen wir, als Gesellschaft, die Bereitstellung von lebensnotwendigen Gütern und Dienstleistungen gestalten? (DIPF/Orig.)

Manfred Liebel: Kinder und Gerechtigkeit. Über Kinderrechte neu nachdenken. Weinheim / Basel: Beltz Juventa 2013 (278 S.) [Rezension]

Rezension von: Manfred Liebel: Kinder und Gerechtigkeit. Über Kinderrechte neu nachdenken. Weinheim / Basel: Beltz Juventa 2013 (278 S.; ISBN 978-3-7799-2837-9)

Neu-eröffnete kunststück des schach-spiels : darinnen nicht allein die unterschiedliche nahmen und gebrauch auch anzahl der steine dieses spiels, bey allerhand nationen, gezeiget wird, als vornehmlich die kunst-griffe dieses spiels,

Mode of access: Internet.