905 resultados para Esteróides fecais - Extração e dosagem


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A presente invenção se refere ao processo de obtenção de compostos derivados de anti-inflamatórios esteróides (AIEs) e de talidomida com propriedades anti-inflamatórias, analgésicas e imunossupressoras úteis no tratamento de processos inflamatórios. A presente invenção se refere também as composições farmacêuticas contendo tais compostos e seus usos na fabricação de medicamentos para o tratamento de doenças inflamatórias principalmente aquelas relacionadas a processos inflamatórios crônicos.

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A presente invenção refere-se a uma droga antiulcerogênica, mais particularmente, a uma droga que compreende uma fração ativa da planta Casearia sylvestris como componente eficaz. De forma particular a invenção trata de uma droga útil no tratamento de distúrbios do trato gastrintestinal, principalmente no tratamento de úlcera gastroduodenal, sendo que apresenta ação citoprotetora, age tanto em úlceras leves como moderadas e graves e, sendo seletiva, não apresenta ação abortiva.

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Chlamydophila psittaci is a bacterium that causes respiratory or systemic disease in birds and humans. Owing to the risk of transmission from asymptomatic birds to humans, the objective of this study was to detect the presence of Chlamydophila spp. in asymptomatic birds. Four hundred and three fecal samples or cloacal swabs were collected from domestic, wild or exotic birds. The 403 samples were examined by real time PCR specific for the 16S subunit of rRNA gene using SsoFastEvaGreen®SupermixTM (Bio-Rad) and melting curve analysis. Hemi-nested PCR specific for the OMP-A gene, accomplished in real-time PCR positive samples, was followed by sequencing of the amplified fragments to determine the genotype of C. psittaci. Real-time PCR was positive in 17 (4.21%) samples. Hemi-nested PCR revealed positivity in two samples previously positive by real-time PCR. Sequencing of the fragment amplified by hemi-nested PCR allowed for the identification of genotype A of C. psittaci in one sample. The results of this experiment show that the real-time PCR targeting the 16S rRNA gene followed by melting curve analysis can be used for diagnosis of Chlamydophila sp. in fecal samples of asymptomatic birds. The classification of the Chlamydophila species and the genotype of C. psittaci must be accomplished by PCR targeting the ompA gene and sequencing of the amplified fragments.

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Common bean grown in no-tillage (NT) systems has increased markedly in Brazil. Thus, to optimize the fertilizer recommendations, it is important to know the nutritional requirements of this crop when grown under new and established NT systems, which can change the nutrient availability and crop response to nitrogen (N) fertilization. The objective was to evaluate the extraction and exportation of nutrients by common bean as function of N fertilization on soil under new and established NT systems. The experiment was carried out in two agricultural years, on a Red Nitosol (Alfisol) in Botucatu, São Paulo State, Brazil. A randomized complete block design was used in a split-plot scheme with four replications. The plots consisted of areas under NT systems after different periods of adoption and the subplots of four forms of N application to common bean (T0: control, without nitrogen; T1: 60 kg ha-1 before sowing; T2: 60 kg ha-1 sidedressed at V4 stage; and T3: 60 kg ha-1 before sowing + 60 kg ha-1 sidedressed). The following properties were evaluated: shoot dry matter, nutrient concentration and accumulation in the shoot, grain yield, and nutrient concentration and exportation in the grains. The NT age did not affect common bean yield, nutrition and response to N management. Nitrogen application, especially before sowing, led to higher dry matter and nutrient accumulation by common bean. The nutrient concentration in grains was little influenced by N fertilization. Grain yield and nutrient exportation were highest after double N application (before sowing and sidedressed) or only sidedressed at V4.

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Pós-graduação em Ciência da Computação - IBILCE

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Pós-graduação em Agronomia - FEIS

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In order to make a histological evaluation of the dental alveolus wound healing in presence of the Isradipine (Lomir/Sandoz Pharma), the new calcium channels blockers, forthy-eight albino rats were utilized. These animals were divided in two groups. The animals of group I were considered as control; in group II, after the dental extractions the rats received intraperitonial injections of 2,5 mg/Kg of isradipine, administered a single dose. From each group of animals were sacrificed at 3, 7, 14 and 21 post-operative days. The pieces were fixed, descalcified and embedded in paraffin. The blocks thus obtained were cut at 6 micrometers thick and sections were stained with hematoxylin and eosin for morphological study. According to the results obtained i t was verified that the treated animals did not alter of wound healing after dental extractions

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)