Influência do aumento energético proveniente de dieta hiperlipídica na disfunção cardíaca em ratos com estenose aórtica supravalvar: participação das cadeias pesadas de miosina e da bomba de cálcio do retículo sarcoplasmático

Pós-graduação em Fisiopatologia em Clínica Médica - FMB

Bioconversão energética da folha e bagaço de mandioca pelo fungo Rhizopus oligosporus para obtenção de alimento funcional

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Efeito do cloprostenol sódico sobre a evolução uterina no puerpério de vacas nelore

Pós-graduação em Medicina Veterinária - FMVZ

CXCL12 estimula fibroblastos pulmonares a produzir CCL3, CXCL2, LTB4 e LTC4 via p38, MEK1/2, PI-3K e JNK

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação de níveis de proteína digestível para girinos de rã-touro

Pós-graduação em Aquicultura - FCAV

Estudo da aromatização pré-extrusão e das condições de extrusão sobre as características físicas e retenção de aroma em proteína isolada de soja

Pós-graduação em Engenharia e Ciência de Alimentos - IBILCE

NaOCl effect on biofilm produced by Staphylococcus aureus isolated from the milking environment and mastitis infected cows

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Chemical and biological properties of phosphorus-fertilized soil under legume and grass cover (Cerrado region, Brazil)

The use of cover crops has been suggested as an effective method to maintain and/or increase the organic matter content, while maintaining and/or enhancing the soil physical, chemical and biological properties. The fertility of Cerrado soils is low and, consequently, phosphorus levels as well. Phosphorus is required at every metabolic stage of the plant, as it plays a role in the processes of protein and energy synthesis and influences the photosynthetic process. This study evaluated the influence of cover crops and phosphorus rates on soil chemical and biological properties after two consecutive years of common bean. The study analyzed an Oxisol in Selvíria (Mato Grosso do Sul, Brazil), in a randomized block, split plot design, in a total of 24 treatments with three replications. The plot treatments consisted of cover crops (millet, pigeon pea, crotalaria, velvet bean, millet + pigeon pea, millet + crotalaria, and millet + velvet bean) and one plot was left fallow. The subplots were represented by phosphorus rates applied as monoammonium phosphate (0, 60 and 90 kg ha-1 P2O5). In August 2011, the soil chemical properties were evaluated (pH, organic matter, phosphorus, potential acidity, cation exchange capacity, and base saturation) as well as biological variables (carbon of released CO2, microbial carbon, metabolic quotient and microbial quotient). After two years of cover crops in rotation with common bean, the cover crop biomass had not altered the soil chemical properties and barely influenced the microbial activity. The biomass production of millet and crotalaria (monoculture or intercropped) was highest. The biological variables were sensitive and responded to increasing phosphorus rates with increases in microbial carbon and reduction of the metabolic quotient.

Composição bromatológica e digestibilidade aparente da parte aérea seca da mandioca na alimentação de tilápias-do-nilo

The objective of this work was to evaluate the effect of sun and shade drying of the aerial part of cassava on the chemical composition and apparent digestibility coefficient (ADC) of nutrients, energy, and aminoacids for Nile tilapia (Oreochromis niloticus). There was no difference between the drying methods for chemical composition. The ADC of crude protein showed higher digestibility for the shade dried aerial part. Shade drying of the aerial part of cassava allows higher conservation of the protein content and better apparent digestibility of the protein and amino acid fraction for Nile tilapia.

Análise do potencial mutagênico dos esteroides anabólicos androgênicos (EAA) e da l-carnitina mediante o teste do micronúcleo em eritrócitos policromáticos

INTRODUCTION: Anabolic androgenic steroids (AAS) are frequently used by people whose aim to increase muscle mass to obtain a better performance in sports or improve physical appearance. AAS are synthetic derivatives of testosterone, able to promote muscle fibers hypertrophy, increasing intracellular protein synthesis. L-carnitine is a food supplement used to increase energetic production by means of fat acids oxidation. Although there are several works about physiological properties of these drugs, there are few studies about their mutagenic potential. OBJECTIVES: This work evaluated the clastogenicity and genotoxicity of nandrolone decanoate, testosterone decanoate and L-carnitine, in different treatments through the micronucleus test in polychromatic erythrocytes of Wistar rats. METHODS: The animals were submitted to different concentrations and associations of AAS. The positive control received cyclophosphamide 50 mg/kg by intraperitoneal injection and negative control, one ml of saline solution by gavage. The rats were sacrificed after 36 hours of latest application, having the femurs removed and the bone marrow extracted. Material was homogenized and centrifuged. Button cell was pipetted and transferred to slides, which were stained by Giemsa. 1,000 polychromatic erythrocytes were counted per animal, noting the frequency of micronuclei. RESULTS: The Kruskal-Wallis test was performed, with a significance level of 5%, which demonstrated that nandrolone decanoate - three doses of 0,2 mg/kg and 0,6 mg/kg, eight doses of 7,5 mg/kg, L-carnitine - seven doses of 0,4 ml/250 g and 1,5 ml/250 g, testosterone decanoate - 28 doses of 0,075 mg/kg, nandrolone decanoate - eight doses of 7,5 mg/kg associated to L-carnitine and 1 mL and nandrolone decanoate - eight doses of 7,5 mg/kg associated to testosterone decanoate - eight doses of 7,5 mg/kg, showed mutagenic potential. CONCLUSION: The treatments proved to be clastogenic, not being indicated like ergogenic aid.

Efeitos da sobrecarga calórica em ratos machos submetidos ou não a restrição protéica in útero

Pós-graduação em Biologia Geral e Aplicada - IBB

Investigação da expressão gênica diferencial em resposta aos efeitos da proteína anti-inflamatória Anexina A1 nas células de carcinoma de colo de útero

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

O efeito da melatonina na angiogênese e metástase de linhagens de carcinoma epidermóide bucal

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Relação nitrogênio não proteico e proteína verdadeira em suplementos na recria de bezerros Nelore

Pós-graduação em Zootecnia - FCAV

Avaliação do efeito da lectina Artin M na expressão de fatores de crescimento e citocinas inflamatórias relacionadas ao processo de repação tecidual: Estudo in vitro em macrófagos e fibroblastos gengivais de ratos

Pós-graduação em Odontologia - FOAR