Moses Parker's Release to Hopkinston [sic] Trustees, 1716 December 21

Handwritten copy of a deed between Moses Parker and the Trustees for the land originally purchased by Parker, et al. from John Owosamog in 1700.

Committee of Natick yr letter of 29th May 1722 to Mr. Leverett, 1722 May 29

One-page handwritten letter signed by Thomas Waban, Solomon Thomas, and Benjamin Tray regarding a "settlement in ye Gospel ministry, among us in our town of Natick."

Hezekiah Squamauge & Amos Ahatton's petition to ye General Court, 1723 December 25

One-page handwritten petition to the Massachusetts General Court on behalf of "Indian inhabitants in Punkapaugue" regarding help with their "lands, and especially as to our orchards, meddows, and to look after our timber, which has been shamfully cutt down, and carried away to our great damage."

[Indenture of Anthony Blount & John Jones to the Trustees of Hopkinton], 1724 March

Handwritten indenture between grantors Anthony Blount and John Jones, and the Trustees as grantees for a parcel of land originally included in Mr. Savill Simpson's farm.

[Plan of a part of Hopkinton, 1824 February 26]

Plat of a part of Hopkinton with houses labeled.

Kitāb al-Itḥāf bi-bayān aḥkām ijārat al-awqāf / li-Khātimat al-Fuqahāʼ al-Muḥaqqiqīn Mawlānā al-ʻAllāmah Aḥmad Shihāb al-Dīn Ibn Ḥajar al-Haytamī al-Makkī : manuscript, 1876

According to the colophon, (f. 63r), copy completed on 14 Ṣafar 1293 AH [March 10, 1876 AD].

The Ukrainian Orthodox Church's stance on the revolution and war. OSW Commentary No. 151, 27.10.2014

Volodymyr (secular name Viktor Sabodan), the Metropolitan of Kyiv and All-Ukraine, the head of the Ukrainian Orthodox Church (UOC), which recognises the honorary primacy of the Moscow Patriarchate, died on 5 July 2014 at the age of 79. He was replaced by Metropolitan Onufry (secular name Orest Berezovsky), aged 70. The fact that this representative of the moderate trend, far from politics, was elected signifies that the UOC’s previous policy will be continued in the coming years: strengthening the Church’s independence without questioning its canonical bonds with Moscow. Metropolitan Onufry’s task is to wait out the hard times, rather than to embark upon an active policy. The political developments this year have significantly weakened pro-Russian views and sentiments among the Ukrainian public, including members of the UOC. On the other hand, they have also contributed to the radicalisation of views within firmly pro-Russian circles. The hierarchs of the Ukrainian Orthodox Church have distanced themselves from these developments. The reasons for this included a lack of unity among them as regards this issue, as well as the leadership crisis linked to Metropolitan Volodymyr’sillness. The main problems the Ukrainian Orthodox Church is facing today are as follows: meeting the expectations of those of its members who hold patriotic views (mainly the younger generation) without at the same time antagonising its numerous members who are pro-Russian; and also continuing to disregard the Kyiv Patriarchate and maintaining bonds with the Russian Orthodox Church. Therefore, we may expect the UOC to continue avoiding taking a clear stance on the present conflict, instead focusing on charity.

Identification of cyclins A1, E1 and vimentin as downstream targets of heme oxygenase-1 in vascular endothelial growth factor-mediated angiogenesis

Angiogenesis is an essential physiological process and an important factor in disease pathogenesis. However, its exploitation as a clinical target has achieved limited success and novel molecular targets are required. Although heme oxygenase-1 (HO-1) acts downstream of vascular endothelial growth factor (VEGF) to modulate angiogenesis, knowledge of the mechanisms involved remains limited. We set out identify novel HO-1 targets involved in angiogenesis. HO-1 depletion attenuated VEGF-induced human endothelial cell (EC) proliferation and tube formation. The latter response suggested a role for HO-1 in EC migration, and indeed HO-1 siRNA negatively affected directional migration of EC towards VEGF; a phenotype reversed by HO-1 over-expression. EC from Hmox1(-/-) mice behaved similarly. Microarray analysis of HO-1-depleted and control EC exposed to VEGF identified cyclins A1 and E1 as HO-1 targets. Migrating HO-1-deficient EC showed increased p27, reduced cyclin A1 and attenuated cyclin-dependent kinase 2 activity. In vivo, cyclin A1 siRNA inhibited VEGF-driven angiogenesis, a response reversed by Ad-HO-1. Proteomics identified structural protein vimentin as an additional VEGF-HO-1 target. HO-1 depletion inhibited VEGF-induced calpain activity and vimentin cleavage, while vimentin silencing attenuated HO-1-driven proliferation. Thus, vimentin and cyclins A1 and E1 represent VEGF-activated HO-1-dependent targets important for VEGF-driven angiogenesis.

The Bedford schools and charities of Sir William Harper : history of this celebrated endowment, the Act of Parliament and scheme of rules for its management, and a memoir of Sir William Harper /

Includes index.

Social welfare laws of the forty-eight states /

Loose-leaf.

R. P. Francisci Suarez, Granatensis, e Societate Iesu doctoris theologi, et in Conimbricensi Academia olim primarij theologiae professoris emeriti, Opus de triplici virtute theologica, fide, spe, et charitate : in tres tractatus, pro ipsarum virtutum numero distributum ...

Title page printed in red and black; title vignette (Jesuit device); head- and tailpieces; initials; printed marginalia.

Annual report.

Mode of access: Internet.

The Charitable trusts acts, 1853 to 1894 (analytically arranged)

At head of title: Charity Commission.

Favorite dishes contributed by the Daughters of the American Revolution /

Includes index.

Penny Mite cook book /

Includes index.