I. The crystal structure of potassium bis(tricyanovinyl)amine. II. Nuclear magnetic resonance studies of alkali halide solutions. III. Elucidation of the intramolecular hydrogen bond in acetylacetone by the deuterium isotope effect on the chemical shift of the bridge hydrogen

<p>Part I</p> <p>Potassium bis-(tricyanovinyl) amine, K⁺N[C(CN)=C(CN)₂]₂^-, crystallizes in the monoclinic system with the space group Cc and lattice constants, a = 13.346 �� 0.003 ��, c = 8.992 �� 0.003 ��, B = 114.42 �� 0.02��, and Z = 4. Three dimensional intensity data were collected by layers perpendicular to b* and c* axes. The crystal structure was refined by the least squares method with anisotropic temperature factor to an R value of 0.064. </p> <p>The average carbon-carbon and carbon-nitrogen bond distances in ���C-C��N are 1.441 �� 0.016 �� and 1.146 �� 0.014 �� respectively. The bis-(tricyanovinyl) amine anion is approximately planar. The coordination number of the potassium ion is eight with bond distances from 2.890 �� to 3.408 ��. The bond angle C-N-C of the amine nitrogen is 132.4 �� 1.9��. Among six cyano groups in the molecule, two of them are bent by what appear to be significant amounts (5.0�� and 7.2��). The remaining four are linear within the experimental error. The bending can probably be explained by molecular packing forces in the crystals.</p> <p>Part II</p> <p>The nuclear magnetic resonance of ⁸¹Br and ¹²⁷I in aqueous solutions were studied. The cation-halide ion interactions were studied by studying the effect of the Li⁺, Na⁺, K⁺, Mg⁺⁺, Cs⁺ upon the line width of the halide ions. The solvent-halide ion interactions were studied by studying the effects of methanol, acetonitrile, and acetone upon the line width of ⁸¹Br and ¹²⁷I in the aqueous solutions. It was found that the viscosity plays a very important role upon the halide ions line width. There is no specific cation-halide ion interaction for those ions such as Mg⁺⁺, Di⁺, Na⁺, and K⁺, whereas the Cs⁺ - halide ion interaction is strong. The effect of organic solvents upon the halide ion line width in aqueous solutions is in the order acetone �� acetonitrile �� methanol. It is suggested that halide ions do form some stable complex with the solvent molecules and the reason Cs⁺ can replace one of the ligands in the solvent-halide ion complex.</p> <p>Part III</p> <p>An unusually large isotope effect on the bridge hydrogen chemical shift of the enol form of pentanedione-2, 4(acetylacetone) and 3-methylpentanedione-2, 4 has been observed. An attempt has been made to interpret this effect. It is suggested from the deuterium isotope effect studies, temperature dependence of the bridge hydrogen chemical shift studies, IR studies in the OH, OD, and C=O stretch regions, and the HMO calculations, that there may probably be two structures for the enol form of acetylacetone. The difference between these two structures arises mainly from the electronic structure of the ��-system. The relative population of these two structures at various temperatures for normal acetylacetone and at room temperature for the deuterated acetylacetone were calculated. </p>

I. Fundamental limitations in microelectronics. II. Power Schottky diode design and comparison with the junction diode. III. Permittivity of strontium titanate

<p>Part I</p> <p>The physical phenomena which will ultimately limit the packing density of planar bipolar and MOS integrated circuits are examined. The maximum packing density is obtained by minimizing the supply voltage and the size of the devices. The minimum size of a bipolar transistor is determined by junction breakdown, punch-through and doping fluctuations. The minimum size of a MOS transistor is determined by gate oxide breakdown and drain-source punch-through. The packing density of fully active bipolar or static non-complementary MOS circuits becomes limited by power dissipation. The packing density of circuits which are not fully active such as read-only memories, becomes limited by the area occupied by the devices, and the frequency is limited by the circuit time constants and by metal migration. The packing density of fully active dynamic or complementary MOS circuits is limited by the area occupied by the devices, and the frequency is limited by power dissipation and metal migration. It is concluded that read-only memories will reach approximately the same performance and packing density with MOS and bipolar technologies, while fully active circuits will reach the highest levels of integration with dynamic MOS or complementary MOS technologies.</p> <p>Part II</p> <p>Because the Schottky diode is a one-carrier device, it has both advantages and disadvantages with respect to the junction diode which is a two-carrier device. The advantage is that there are practically no excess minority carriers which must be swept out before the diode blocks current in the reverse direction, i.e. a much faster recovery time. The disadvantage of the Schottky diode is that for a high voltage device it is not possible to use conductivity modulation as in the p i n diode; since charge carriers are of one sign, no charge cancellation can occur and current becomes space charge limited. The Schottky diode design is developed in Section 2 and the characteristics of an optimally designed silicon Schottky diode are summarized in Fig. 9. Design criteria and quantitative comparison of junction and Schottky diodes is given in Table 1 and Fig. 10. Although somewhat approximate, the treatment allows a systematic quantitative comparison of the devices for any given application.</p> <p>Part III</p> <p>We interpret measurements of permittivity of perovskite strontium titanate as a function of orientation, temperature, electric field and frequency performed by Dr. Richard Neville. The free energy of the crystal is calculated as a function of polarization. The Curie-Weiss law and the LST relation are verified. A generalized LST relation is used to calculate the permittivity of strontium titanate from zero to optic frequencies. Two active optic modes are important. The lower frequency mode is attributed mainly to motion of the strontium ions with respect to the rest of the lattice, while the higher frequency active mode is attributed to motion of the titanium ions with respect to the oxygen lattice. An anomalous resonance which multi-domain strontium titanate crystals exhibit below 65��K is described and a plausible mechanism which explains the phenomenon is presented.</p>

E. U. Magisterio de Vitoria-Gasteiz. Plan general Practicum III. Comisi��n de pr��cticas, 4 de julio de 2014

[ES]Las Pr��cticas Escolares se realizar��n en los dos ciclos de Educaci��n Infantil (0-3, 3-6) y en los tres de Educaci��n Primaria (1��-2��, 3��-4��, 5��-6��). Al tratarse de un Pr��cticum progresivo, cada estudiante cursa la materia a lo largo del segundo, tercer y cuarto curso (Pr��cticum I, Pr��cticum II y Pr��cticum III) con contenidos que tienen continuidad y que suponen un nivel de competencia superior respecto el anterior. Adem��s, el alumnado que en 4�� curso se matricule en el minor de Educaci��n F��sica deber�� realizar su periodo de pr��cticas junto a una maestra o maestro especialista en esta materia, quien tutorizar�� sus pr��cticas. El Pr��cticum supone para el alumnado una oportunidad de adquirir e integrar las habilidades, los conocimientos, las competencias y la pr��ctica necesarios para el ejercicio de su profesi��n, as�� como una ocasi��n para reflexionar de forma individual y grupal acerca del aprendizaje realizado y de la pr��ctica llevada a cabo.

Ex��menes resueltos de matem��ticas III LADE

En la asignatura de Matem��ticas III, en la Licenciatura en Administraci��n y Direcci��n de Empresas, se complementan los estudios de Algebra Lineal introducidos en Matem��ticas I y se estudian en profundidad los problemas de programaci��n lineal, imprescindibles en estos estudios. En la primera parte de esta asignatura se aborda el problema de la diagonalizaci��n de matrices y el estudio de las formas cuadr��ticas. La segunda parte de la asignatura se dedica a la programaci��n lineal, incidiendo especialmente en el an��lisis gr��fico de este tipo de tipo de problemas y en el m��todo simplex, que permite resolver estos problemas cuando el n��mero de variables aumenta. As�� mismo, se insiste en el correcto planteamiento de estos problemas y en el an��lisis de sensibilidad. Todos estos conceptos son necesarios en los estudios de Administraci��n y Direcci��n de Empresas (LADE). Esta publicaci��n recoge la resoluci��n de todos los ex��menes propuestos en la asignatura de Matem��ticas III, Licenciatura en Administraci��n y Direcci��n de Empresas, en la Facultad de Ciencias Econ��micas y Empresariales de la UPV\EHU entre los cursos 2001-2002 y 2009-2010. Los ex��menes est��n dispuestos en el orden en que se realizaron, esto es, los ��ltimos que aparecen son los m��s recientes.

Relaci��n de problemas resueltos de ex��menes de la asignatura Matem��ticas III para Economistas de la Licenciatura de Econom��a

Relaci��n de problemas resueltos de ex��menes de la asignatura Matem��ticas III para Economistas de la Licenciatura de Econom��a desde febrero de 2001 hasta junio de 2010.

Zientzia eta Teknologia Fakultateko III. Ikerkuntza Jardunaldiak ; Enpresa eta Berrikuntza Teknologikoko Zentroen Aurkezpenerako VII. Jardunaldiak

[ES]El objetivo de estas jornadas es, por una parte, mostrar a nuestro alumnado la investigaci��n que llevan a cabo los diferentes grupos de la facultad, de cara a despertar vocaciones investigadoras. Por otro lado, como en otras ocasiones, varias empresas y centros de innovaci��n tecnol��gica presentar��n al alumnado de los ��ltimos cursos las posibilidades y los requisitos para su incorporaci��n al mundo laboral

Condi����es de sa��de bucal em atletas dos XV Jogos Pan-Americanos e III Jogos Parapan-Americanos, Rio de Janeiro, Brasil, 2007

O estudo epidemiol��gico transversal randomizado objetivou avaliar condi����es de sa��de bucal nos competidores dos XV Jogos Pan-Americanos (JPA) e III Jogos Parapan-Americanos (JPPA), 2007. Foram enviados convites para 5.662 atletas (JPA) e 1.300 (JPPA). Radiografias panor��micas digitais (RPD) foram utilizadas para o exame de triagem nos 2 eventos, e nos JPPA, os atletas tamb��m foram submetidos �� avalia����o do sangramento gengival interdental (SI) atrav��s de uma vers��o modificada do ��ndice de Sangramento Interdental de Eastman (EIBI). Foram obtidas RPDs de 410 atletas dos JPA, m��dia de idade 24,38 (dp5,35), 55% homens; e de 118 dos atletas dos JPPA, m��dia de idade de 32,3 (dp9,53), 77,97% homens. 121 competidores (JPPA) foram avaliados para SI: 78,51% homens, m��dia de idade 32,6(dp9,6), e foram separados em grupos (G), conforme sua defici��ncia f��sica: GI c/ defici��ncia visual (DV), com 2 subgrupos: GI-a: DV tardia e GI-c-: DV cong��nita/precoce; GII- defici��ncia de membro superior; com 1 subgrupo: GII-t: defici��ncia/aus��ncia bilateral; GIII- defici��ncia de membro inferior (grupo controle). As RPDs foram examinadas por 1 examinador com o Kodak Dental Imaging(v6.7). A frequ��ncia e a distribui����o do SI foram calculadas, e os grupos foram comparados. Resultados da triagem com RPDs, representados por n��mero de observa����es(m��dia por atleta) JPA//n��mero de observa����es(m��dia por atleta JPPA: Dentes erupcionados/ h��gidos: 9097(22,19)//2451(20,77); Ausentes: 803(1,96 //405(3,43); N��o erupcionados ou impactados: 330(0,80)//52(0,44); Parcialmente erupcionados e/ou h��gidos: 109(0,27)//20(0,17); C��rie extensa: 261(0,64)//62(0,53); C��rie extensa e les��o periapical: 96(0,23)//50(0,42); Tratamento endod��ntico e les��o periapical: 24(0,06)//13(0,11); Restaurados: 2298(5,60)//670(5,68); Imagens radiol��cidas patol��gicas circunscritas: 23(0,06)//0; Ra��zes-residuais: 27(0,07)//22(0,19); Implantes:6(0,01)//5(0,04); Dentes anteriores fraturados: 13 (0,03)//3(0,03); Molares bandados: 26(0,06)//11(0,09); Dentes an��malos: 7(0,02)//12(0,10). Resultados para SI: G-I>G-III (p=0.0002);GI-c>GI-a (p=0,042). Homens exibiram > freq����ncia de SI (3,6%+1,7) que mulheres (0,8%+0,5), p<0,01. Conclus��es: Os dados das 2 popula����es de atletas mostraram que h�� uma grande varia����o na sa��de bucal entre os indiv��duos avaliados. Diversas condi����es com potencial de influenciar o desempenho esportivo dos atletas foram detectadas atrav��s de radiografias panor��micas digitais, sugerindo que um programa de sa��de bucal deve ser inclu��do como parte da prepara����o destes indiv��duos.A avalia����o da frequ��ncia e distribui����o de sangramento gengival interdental em uma popula����o de atletas que competiu nos III Jogos Parapan-Americanos, revelou que o tipo de defici��ncia ou limita����o f��sica dos competidores �� um fator que influencia na sa��de gengival desses indiv��duos. O planejamento de um programa de sa��de bucal para esta popula����o deve ser adaptado ��s diferentes limita����es de cada atleta.

Efficacy and safety of autologous platelet rich plasma for the treatment of vascular ulcers in primary care: Phase III study

Background: Vascular ulcers are commonly seen in daily practice at all levels of care and have great impact at personal, professional and social levels with a high cost in terms of human and material resources. Given that the application of autologous platelet rich plasma has been shown to decrease healing times in various different studies in the hospital setting, we considered that it would be interesting to assess the efficacy and feasibility of this treatment in primary care. The objectives of this study are to assess the potential efficacy and safety of autologous platelet rich plasma for the treatment of venous ulcers compared to the conventional treatment (moist wound care) in primary care patients with chronic venous insufficiency (C, clinical class, E, aetiology, A, anatomy and P, pathophysiology classification C6). Design: We will conduct a phase III, open-label, parallel-group, multicentre, randomized study. The subjects will be 150 patients aged between 40 and 100 years of age with an at least 2-month history of a vascular venous ulcer assigned to ten primary care centres. For the treatment with autologous platelet rich plasma, all the following tasks will be performed in the primary care setting: blood collection, centrifugation, separation of platelet rich plasma, activation of coagulation adding calcium chloride and application of the PRP topically after gelification. The control group will receive standard moist wound care. The outcome variables to be measured at baseline, and at weeks 5 and 9 later include: reduction in the ulcer area, Chronic Venous Insufficiency Quality of Life Questionnaire score, and percentage of patients who require wound care only once a week. Discussion: The results of this study will be useful to improve the protocol for using platelet rich plasma in chronic vascular ulcers and to favour wider use of this treatment in primary care.

Caracteriza����o das les��es impalp��veis (les��es III E IV), e das altera����es em TP53 (p53) na detec����o precoce do c��ncer de mama

As les��es impalp��veis da mama que muitas das vezes s��o assintom��ticas, podem corresponder �� um est��gio de progress��o de c��ncer dif��cil de ser detectado, durante os exames de rotina de palpa����o da mulher. O ��nico m��todo poss��vel para a descoberta dessas les��es �� atrav��s dos exames de imagem da mama, de modo geral, atrav��s da mamografia, que geralmente ocorre ap��s os 45 anos. Devido a esses fatores, les��es impalp��veis, s��o frequentemente, descobertas apenas quando o est��gio de desenvolvimento da doen��a j�� est�� avan��ado e as interven����es terap��uticas s��o menos reparadoras. Com a finalidade de iniciar a caracteriza����o de tumores impalp��veis iniciais, objetivamos analisar o perfil gen��tico (muta����o) e epigen��tico (metila����o de regi��o promotora) de regi��es do DNA relacionadas ao gene supressor tumoral TP53, provenientes de bi��psias de mulheres residentes do Estado do Rio de Janeiro. Neste trabalho, foram investigadas 34 amostras de tecido de tumor de mama, por sequenciamento de DNA, nos exons de 5 a 8 do gene TP53. Nesta regi��o, n��o foi encontrada nenhuma muta����o. Este resultado pode estar relacionado ao tipo inicial de les��o, de acordo com os dados radiol��gicos das les��es de categorias 3 e 4 da escala BIRADS. Para verificar o estado de metila����o da regi��o promotora do gene TP53, analisamos 30 pares de amostras (sangue e tumor) de pacientes com suspeita de c��ncer de mama, pela t��cnica MSP-PCR. Nenhuma amostra tumoral apresentou altera����o no estado de metila����o na regi��o promotora do gene TP53, quando comparada �� amostra normal. Um motivo poss��vel para a disparidade de resultados em rela����o �� outros trabalhos pode ter sido a utiliza����o da t��cnica. A caracteriza����o das les��es impalp��veis apenas foi iniciada neste trabalho, no qual pudemos constatar que a muta����o em TP53 pode ser um evento mais tardio. Portanto, a les��o mam��ria, em suas diferentes formas, continuar�� a ser o assunto investigado por nosso grupo, ampliando o n��mero de amostras e alcan��ando melhor conex��o da conduta e dos m��todos cl��nicos j�� existentes, com as novas possibilidades de diagn��stico via marcadores moleculares em tumores e fluidos biol��gicos

Variation saisonniere des structures hydrologique et dynamique du plateau continental ivoirien (VASPI I, II, III)

This data report contains all the meteorological, hydrological and dynamic data gathered during the VASPI cruises (I : from December 8th to December 13th 1982, II : from March 5th to March 9th 1983, and III : from October 6th to October 10th 1983) carried out along the continental shelf of Ivory Coast by the oceanographic ship "Andre NIZERY". These cruises, which represent a part of a coastal programme, are included in the more general scientific program FOCAL, whose main scientific objective is the study of the thermal context of the intertropical atlantic area.