Association of oliguria with the development of acute kidney injury in the critically ill

Urine output (UO) criterion may increase the sensitivity of the definition of acute kidney injury (AKI). We determined whether the empirically derived definition for oliguria(<0.5 ml/kg/h) is independently associated with adverse outcome. Data analysis included hourly recorded UO from the prospective, multicenter FINNAKI study conducted in 16 Finnish intensive care units. Confounder-adjusted association of oliguria of different severity and duration primarily with the development of AKI defined by creatinine criterion (Cr-AKI) or renal replacement therapy(RRT) was assessed. Secondarily, we determined the association of oliguria with 90-day mortality. Of the 1966 patients analyzed for the development of AKI, 454 (23.1%) reached this endpoint. Within this AKI cohort, 312 (68.7%)developed Cr-AKI, 21 (4.6%) commenced RRT without Cr-AKI, and 121 (26.7%) commenced RRT with Cr-AKI. Episodes of severe oliguria (<0.1 ml/kg/h) for more than 3 h were independently associated with the development of Cr-AKI or RRT. The shortest periods of consecutive oliguria independently associated with an increased risk for 90-day mortality were 6–12 h of oliguria from 0.3 to <0.5 ml/kg/h, over 6 h of oliguria from 0.1 to <0.3 ml/kg/h, and severe oliguria lasting over 3 h.Thus, our findings underlie the importance of hourly UO measurements.

Standardized reporting using CODES (Crash Outcome Data Evaluation System).

National Highway Traffic Safety Administration, Washington, D.C.

Pedestrian injury causation parameters. Phase II. Final report.

National Highway Traffic Safety Administration, Washington, D.C.

Special training in injury coding. Final report.

National Highway Traffic Safety Administration, Washington, D.C.

Evaluation of minimum drinking age laws using the National Electronic Injury Surveillance System. Final report.

Mode of access: Internet.

Evaluation of state motorcycle helmet laws using the National Electronic Injury Surveillance System. Final report.

Mode of access: Internet.

Injury scaling research. Final report.

National Highway Traffic Safety Administration, Washington, D.C.

The crash outcome data evaluation system (CODES).

National Highway Traffic Safety Administration, Office of Research and Development, Washington, D.C.

Motorcycle accident cause factors and identification of countermeasures. Volume II: appendix/supplemental data. Final report.

National Highway Traffic Safety Administration, Washington, D.C.

Transformation of Nine-Accelerometer-Package (NAP) data for replicating headpart kinematics and dynamic loading. Final report.

National Highway Traffic Safety Administration, Washington, D.C.

Injury coding manual - 1980. Final report.

National Highway Traffic Safety Administration, National Center for Statistics and Analysis, Washington, D.C.

Evaluation of an injury reporting and information system (IRIS) for the solid waste management industry : final report /

"SW-169.1-3."

Report to Congress: benefits of safety belts and motorcycle helmets. Based on data from the Crash Outcome Data Evaluation System (CODES).

Mode of access: Internet.

National Center for Statistics and Analysis collected technical studies. Volume I: accident data analysis of vehicle crashworthiness - ten papers.

Mode of access: Internet.

Analysis of vehicle injury sources. Final report. Revised.

National Highway Traffic Safety Administration, Washington, D.C.