Beryllium ages, sedimentology and weathering characteristics of Reedy Glacier deposits

Deposits corresponding to multiple periods of glaciation are preserved in ice-free areas adjacent to Reedy Glacier, southern Transantarctic Mountains. Glacial geologic mapping, supported by 10Be surface-exposure dating, shows that Reedy Glacier was significantly thicker than today multiple times during the mid-to-late Cenozoic. Longitudinal-surface profiles reconstructed from the upper limits of deposits indicate greater thickening at the glacier mouth than at the head during these episodes, indicating that Reedy Glacier responded primarily to changes in the thickness of the West Antarctic Ice Sheet. Surface-exposure ages suggest this relationship has been in place since at least 5 Ma. The last period of thickening of Reedy Glacier occurred during Marine Isotope Stage 2, at which time the glacier surface near its confluence with the West Antarctic Ice Sheet was at least 500 m higher than today.

Análisis de la cadena de valor del sector ovino en Salinas, San Luis de Potosí, México

El concepto de cadena de valor se ha utilizado para el diagnóstico e identificación de soluciones a los problemas que enfrenta una actividad determinada. En este trabajo de investigación se analiza la cadena de valor desde el enfoque de la integración social y el establecimiento de vínculos entre los actores que intervienen: productores, minoristas, mayoristas, transformadores, comercializadores y organizaciones locales. La metodología usada incluye: 1) identificación del sector; 2) identificación de agentes; 3) análisis de la cadena de valor; 4) análisis de agentes y, 5) estrategia de cooperación. La investigación se realizó en el municipio de Salinas, San Luis Potosí, México. Se obtuvo la información de campo mediante encuestas y entrevistas estructuradas. Los datos señalan que la cadena de valor del sector ovino en Salinas se encuentra en un nivel bajo de competitividad. Además que se encuentra desarticulada en lo que se refiere tanto a las relaciones horizontales como a las verticales. Es recomendable fomentar la capacitación y asistencia técnica en las distintas áreas del manejo de la especie: alimentación, reproducción, transformación del producto y comercialización

Análisis de la cadena de valor del queso manchego en Cuenca, España

El concepto de cadena de valor, se ha desarrollado como respuesta a la necesidad para que las empresas rurales, cumplan con las exigencias de la demanda de productos especializados de alta calidad. En este trabajo se realiza un análisis de la cadena de valor del queso manchego en Cuenca, España; identificando a los agentes y las relaciones entre ellos; en donde se tiene una importante producción de queso manchego con denominación de origen. La investigación se llevó a cabo durante 2008 en la Provincia de Cuenca, España. La metodología que se utiliza incluye las siguientes fases: 1) identificación del sector; 2) identificación de agentes; 3) análisis de la cadena de valor; y 4) análisis de agentes. Los resultados obtenidos presentan que los principales factores que están influyendo en el desarrollo de la cadena de valor son: integración horizontal y vertical, confianza entre agentes, acceso y uso de financiamiento, cumplimiento de normas gubernamentales, cumplimiento de normas de la denominación de origen. Por lo anterior, se concluye que dicha cadena está funcionando correctamente y pueden tomarse elementos de éxito para adecuarse a otros territorios.

Simulacion del analisis de riesgos en la gestion de proyectos como herramienta en el proceso de formacion de ingenieros civiles

El programa de Ingeniería Civil en la Universidad Autónoma de Coahuila es el resultado de un proceso de Acreditación y Revisión constante, el cual da respuesta a la creciente demanda social de Gestión de Proyectos, aun cuando en la práctica es severamente cuestionada por la poca aplicación de los escenarios de modelación; por lo que, la investigación que se desarrolla por parte de la Cátedra de Proyectos nos permite fomentar el estudio de las Variables de Riesgo con el fin de establecer de manera eficiente un marco de referencia que permita incrementar el conocimiento de esta herramienta como material didáctico en la materia de Gestión de Proyectos. De esta manera, en la investigación se exponen las técnicas de identificación, los modelos de análisis y las herramientas de modelación que desarrollen las habilidades y actitudes en la toma de decisión, atendiendo a los criterios establecidos por los PMC, DIP, PMP; esto, con el fin de apoyar los trabajos de Gestión de Proyectos en escenarios críticos

Noise-induced attractor annihilation in the delayed feedback logistic map

We study dynamics of the bistable logistic map with delayed feedback, under the influence of white Gaussian noise and periodic modulation applied to the variable. This system may serve as a model to describe population dynamics under finite resources in noisy environment with seasonal fluctuations. While a very small amount of noise has no effect on the global structure of the coexisting attractors in phase space, an intermediate noise totally eliminates one of the attractors. Slow periodic modulation enhances the attractor annihilation.

COMUNICAÇÃO ESTRATÉGICA DE IES ATRAVÉS DO HANDEBOL DE ALTO RENDIMENTO

A tese aborda como a Universidade Metodista de São Paulo (UMESP) e a Universidade de Taubaté (UNITAU) utilizam o esporte de alto rendimento como meio de divulgação estratégica. O estudo mostra qual é a relação existente entre a comunicação institucional e mercadológica das referidas IES e o handebol de alto rendimento. A tese objetiva também, apresentar as ferramentas de comunicação utilizadas por UMESP e UNITAU para divulgar suas ações de patrocínio e, por fim, avaliar o grau do fluxo de comunicação dos profissionais de comunicação e marketing das IES com gestores esportivos do handebol. A comparação entre as IES analisadas deu-se pelo uso do método de pesquisa de ‘estudos de casos múltiplos’, já a pesquisa documental e a bibliográfica foram utilizadas para a construção teórica do trabalho. Os dados dos objetos de estudo foram coletados através do uso da técnica de entrevista, estas que, adotaram a característica ‘semiestruturada’ com perguntas abertas e uso de roteiro. Concluiu-se que as universidades UMESP e UNITAU pouco exploram a imagem vitoriosa do handebol de alto rendimento que investem como meio estratégico de divulgação

A MULHER ALÉM DO BEM E DO MAL: Malévola e a representação cinematográfica do feminino integrado

Estudo sobre as construções simbólicas e identitárias da mulher presentes na narrativa e na estrutura das personagens femininas do filme Malévola (2014) – produção dos estúdios Disney (EUA). A narrativa é inspirada no conto de fadas “A Bela Adormecida do Bosque” e distingue-se pela perspectiva feminina, modificando as possibilidades de interpretação, além de possibilitar a quebra do paradigma dicotômico relacionado ao Bem e ao Mal. A pesquisa tem por objetivo estudar a evolução das construções imaginárias da mulher no cinema e traçar paralelos entre as características arquetípicas das personagens de Malévola em relação à identidade da mulher na contemporaneidade. Para tal, será tomado como referencial teórico os estudos do imaginário social, com as obras de Gilbert Durand, Edgar Morin e, em especial, Michel Maffesoli; conceitos da psicanálise a partir dos trabalhos de C.G. Jung, Erich Neumann, Marie-Louise Von Franz e Clarissa Pinkola Estés; as teorias de Stuart Hall, Laura Mulvey e Gilles Lipovetsky relacionadas aos estudos culturais com ênfase em gênero; e também o ecofeminismo através dos trabalhos de autoras como Vandana Shiva e Maria Mies. Nosso referencial teórico-metodológico é a Hermenêutica de Profundidade (HP) visando à interpretação da estrutura simbólica de nosso objeto. Resultam desta pesquisa a verificação de um processo de saturação de padrões identitários e simbólicos provindos da modernidade e a evolução de novas dinâmicas nas narrativas presentes nas mídias e na comunicação

Interactions among enzymes of the Arabidopsis flavonoid biosynthetic pathway

Flavonoids are secondary metabolites derived from phenylalanine and acetate metabolism that perform a variety of essential functions in higher plants. Studies over the past 30 years have supported a model in which flavonoid metabolism is catalyzed by an enzyme complex localized to the endoplasmic reticulum [Hrazdina, G. & Wagner, G. J. (1985) Arch. Biochem. Biophys. 237, 88–100]. To test this model further we assayed for direct interactions between several key flavonoid biosynthetic enzymes in developing Arabidopsis seedlings. Two-hybrid assays indicated that chalcone synthase, chalcone isomerase (CHI), and dihydroflavonol 4-reductase interact in an orientation-dependent manner. Affinity chromatography and immunoprecipitation assays further demonstrated interactions between chalcone synthase, CHI, and flavonol 3-hydroxylase in lysates from Arabidopsis seedlings. These results support the hypothesis that the flavonoid enzymes assemble as a macromolecular complex with contacts between multiple proteins. Evidence was also found for posttranslational modification of CHI. The importance of understanding the subcellular organization of elaborate enzyme systems is discussed in the context of metabolic engineering.

Biological stress systems, adverse life events and the onset of chronic multisite musculoskeletal pain : a 6-year cohort study

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Folding in vivo of a newly translated yeast cytosolic enzyme is mediated by the SSA class of cytosolic yeast Hsp70 proteins

The nature of chaperone action in the eukaryotic cytosol that assists newly translated cytosolic proteins to reach the native state has remained poorly defined. Actin, tubulin, and Gα transducin are assisted by the cytosolic chaperonin, CCT, but many other proteins, for example, ornithine transcarbamoylase (OTC), a cytosolic homotrimeric enzyme of yeast, do not require CCT action. Here, we observe that yeast cytosolic OTC is assisted to its native state by the SSA class of yeast cytosolic Hsp70 proteins. In vitro, refolding of OTC diluted from denaturant was assisted by crude yeast cytosol and ATP and found to be directed by SSA1/2. In vivo, when OTC was induced in a temperature-sensitive SSA-deficient strain, it exhibited reduced specific activity, and nonnative subunits were detected in the soluble fraction. These findings indicate that, in vivo, the Hsp70 system assists in folding at least some newly translated cytosolic enzymes, most likely functioning in a posttranslational manner.

A CDKN2-like polymorphism in Xiphophorus LG V is associated with UV-B-induced melanoma formation in platyfish–swordtail hybrids

The genetic basis of spontaneous melanoma formation in spotted dorsal (Sd) Xiphophorus platyfish–swordtail hybrids has been studied for decades, and is adequately explained by a two-gene inheritance model involving a sex-linked oncogene, Xmrk, and an autosomal tumor suppressor, DIFF. The Xmrk oncogene encodes a receptor tyrosine kinase related to EGFR; the nature of the DIFF tumor suppressor gene is unknown. We analyzed the genetic basis of UV-B-induced melanoma formation in closely related, spotted side platyfish–swordtail hybrids, which carry a different sex-linked pigment pattern locus, Sp. We UV-irradiated spotted side Xiphophorus platyfish–swordtail backcross hybrids to induce melanomas at frequencies 6-fold higher than occur spontaneously in unirradiated control animals. To identify genetic determinants of melanoma susceptibility in this UV-inducible Xiphophorus model, we genotyped individual animals from control and UV-irradiated experimental regimes using allozyme and DNA restriction fragment length polymorphisms and tested for joint segregation of genetic markers with pigmentation phenotype and UV-induced melanoma formation. Joint segregation results show linkage of a CDKN2-like DNA polymorphism with UV-B-induced melanoma formation in these hybrids. The CDKN2-like polymorphism maps to Xiphophorus linkage group V and exhibits recombination fractions with ES1 and MDH2 allozyme markers consistent with previous localization of the DIFF tumor suppressor locus. Our results indicate that the CDKN2-like sequence we have cloned and mapped is a candidate for the DIFF tumor suppressor gene.