Rural health care research : impacting vulnerable populations.

"AHCPR91-0013"--P. [4].

'You Never Truly Feel at Home': Students' Perceptions of their Multilingualism and its Role in their Identity Construction : - A Study Performed in a Suburb Located in a Socially Vulnerable Area

A relevant subject in our globalized world concerns the relationship between language and identity, specifically amongst migrant youngsters’ experience of group belonging. This study therefore focused on how adolescents born to foreign parents in Sweden, perceived their multilingualism as part of their identity formation. I also aimed to include how socio-economic aspects could affect the process of identity construction. Thus, the investigation was performed with seventh grade students at a primary school located in the Stockholm suburb Bredäng. The methods consisted of a questionnaire, which was completed by the entire class and a group interview where six students participated. The results revealed that students adapted their language use based on the context, but Swedish was used most habitually. The informants viewed their multilingualism as beneficial but yet fully aware of the linguistic ideologies functioning in society. By combining their minority and majority language, the students were left with different ethnic identities and had diverse interpretations of what it meant to be Swedish. Even though all of them perceived themselves to have multiple ethnic identities, this was not solely seen positively. The issue of belonging was raised and the students claimed to be outcasts everywhere. However, the results differed depending on whether the students were born in Sweden or not. Also, most of them struggled with the process of assumed and ascribed identities, since they perceived themselves to be Swedish but experienced that society valued them as immigrants. Lastly, the study revealed that there were connections between their multilingualism and social mobility as the relationship towards the motherland was highly prioritized even with low levels of economic capital. 

The Vulnerable Animals That Therefore We Are : (Non-)Human Animals in D.H. Lawrence's Women in Love

Central to animal studies is the question of words and how they are used in relation to wordless beings such as non-human animals. This issue is addressed by the writer D.H. Lawrence, and the focus of this thesis is the linguistic vulnerability of humans and non-humans in his novel Women in Love, a subject that will be explored with the help of the philosopher Jacques Derrida’s text The Animal That Therefore I Am. The argument is that Women in Love illustrates the human subjection to and constitution in language, which both enables human thinking and restricts the human ability to think without words. This linguistic vulnerability causes a similar vulnerability in non-human animals in two ways. First, humans tend to imagine others, including non-verbal animals, through words, a medium they exist outside of and therefore cannot be defined through. Second, humans are often unperceptive of non-linguistic means of expression and they therefore do not discern what non-human animals may be trying to communicate to them, which often enables humans to justify abuse against non-humans. In addition, the novel shows how this shared but unequal vulnerability can sometimes be dissolved through the likewise shared but equal physical vulnerability of all animals if a human is able to imagine the experiences of a non-human animal through their shared embodiment rather than through human language. Hence the essay shows the importance of recognizing the limitations of language and of being aware of how the symbolizing effect of words influences the human treatment of its others.

Juventud vulnerable y escuela media : Representaciones y experiencias sobre la autoridad escolar. Algunos avances de investigación

La crisis de autoridad en la escuela media se presenta hoy como un problema crítico y creciente; los jóvenes representan para la institución tradicional el desafío de la incertidumbre y en escuelas de sectores desfavorecidos la imprevisibilidad es aún mayor, dado que las culturas juveniles de las barriadas populares están atravesadas por problemas vinculados con las drogas, el mundo de la economía informal e ilegal y fenómenos de violencia y tribalidad expresadas en luchas de bandos por el dominio de territorios (Duschatsky, 1999; Tessio Conca, 2007). Estas problemáticas plantean un estado de perplejidad en docentes y responsables de las escuelas, al verse desbordados ante condiciones que exceden ampliamente lo estrictamente pedagógico y que ponen en jaque cotidianamente sus formas tradicionales de sostener la autoridad. En esta ponencia presentaremos avances de una investigación en curso en la ciudad de Córdoba en la que se indaga acerca de las representaciones y experiencias sobre la autoridad escolar de grupos juveniles en situación de vulnerabilidad social. Expondremos aquí las consideraciones teóricas que sirven de marco al trabajo, así como algunos resultados preliminares de discusiones focales con grupos de estudiantes que concurren a escuelas secundarias de barrios populares de Córdoba Capital

L.I.F.E. Landscape: A Co-created Healing Environment for Vulnerable Maasai Youth

Thesis (Master's)--University of Washington, 2016-06

The effects of high glucose and atorvastatin on endothelial cell matrix production

Background Statins are known to enhance atherosclerotic plaque stability through influences on extracellular matrix homeostasis. Net matrix production reflects the relative balance of matrix production and degradation through enzymes such as matrix metalloproteinases (MMPs) and their inhibitors, tissue inhibitor of MMP (TIMPs). The effects of statins on endothelial cell production of these parameters following co-exposure with a proatherogenic stimulus such as high glucose are not known. Methods Human endothelial cells were exposed for 72 h to 5 mM> (control) or 25 mM (high) glucose +/- atorvastatin (1 mumol/l). Extracellular matrix homeostasis was assessed by measuring matrix metalloproteinase (MMP)-2 secretion, tissue inhibitor of MMP (TIMP)-1 and -2 secretion and net collagen IV production. Results were expressed as percentage +/- SEM of control values. Results Exposure to high glucose increased cellular collagen IV expression to 190.1 +/- 11.7% (P < 0.0001) of control levels. No change in MMP-2 secretion (111.6 +/- 5.2%; P > 0.05) was observed but both TIMP-1 and TIMP-2 expression were increased to 136.3 +/- 6.4% and 144.0 +/- 27.5%, respectively (both P < 0.05). The presence of atorvastatin in high glucose conditions reduced collagen IV expression to 136.1 +/- 20.6%. This was paralleled by increased secretion of MMP-2 to 145.8 +/- 7.8% (P < 0.01), increased TIMP-2 expression to 208.0 +/- 21.3% (P < 0.005 compared with high glucose) but no change in TIMP-1 expression (155.1 +/- 14.6%) compared with high glucose alone. The presence of atorvastatin in control conditions did not affect levels of collagen IV expression (114.5 +/- 13.2%). Conclusions Endothelial cell exposure to high glucose was associated with a MMP/TIMP profile that increased extracellular matrix production which was attenuated by concurrent exposure to atorvastatin. Consequently, a mechanism by which the atherosclerotic plaque regression that is observed in patients taking these drugs has been demonstrated.

Multiple genotypes of Chlamydia pneumoniae identified in human carotid plaque

Chlamydia pneumoniae is an obligate intracellular respiratory pathogen that causes 10% of community-acquired pneumonia and has been associated with cardiovascular disease. Both whole-genome sequencing and specific gene typing suggest that there is relatively little genetic variation in human isolates of C. pneumoniae. To date, there has been little genomic analysis of strains from human cardiovascular sites. The genotypes of C. pneumoniae present in human atherosclerotic carotid plaque were analysed and several polymorphisms in the variable domain 4 (VD4) region of the outer-membrane protein-A (ompA) gene and the intergenic region between the ygeD and uridine kinase (ygeD-urk) genes were found. While one genotype was identified that was the same as one reported previously in humans (respiratory and cardiovascular), another genotype was found that was identical to a genotype from non-human sources (frog/koala).