Mass-movement and flood-induced deposits in Lake Ledro, southern Alps, Italy: implications for Holocene palaeohydrology and natural hazards

High-resolution seismic profiles and sediment cores from Lake Ledro combined with soil and riverbed samples from the lake's catchment area are used to assess the recurrence of natural hazards (earthquakes and flood events) in the southern Italian Alps during the Holocene. Two well-developed deltas and a flat central basin are identified on seismic profiles in Lake Ledro. Lake sediments have been finely laminated in the basin since 9000 cal. yr BP and frequently interrupted by two types of sedimentary events (SEs): light-coloured massive layers and dark-coloured graded beds. Optical analysis (quantitative organic petrography) of the organic matter present in soil, riverbed and lacustrine samples together with lake sediment bulk density and grain-size analysis illustrate that light-coloured layers consist of a mixture of lacustrine sediments and mainly contain algal particles similar to the ones observed in background sediments. Light-coloured layers thicker than 1.5 cm in the main basin of Lake Ledro are synchronous to numerous coeval mass-wasting deposits remoulding the slopes of the basin. They are interpreted as subaquatic mass-movements triggered by historical and pre-historical regional earthquakes dated to AD2005, AD1891, AD1045 and 1260, 2545, 2595, 3350, 3815, 4740, 7190, 9185 and 11 495 cal. yr BP. Darkcoloured SEs develop high-amplitude reflections in front of the deltas and in the deep central basin. These beds are mainly made of terrestrial organic matter (soils and lignocellulosic debris) and are interpreted as resulting from intense hyperpycnal flood event. Mapping and quantifying the amount of soil material accumulated in the Holocene hyperpycnal flood deposits of the sequence allow estimating that the equivalent soil thickness eroded over the catchment area reached up to 5mm during the largest Holocene flood events. Such significant soil erosion is interpreted as resulting from the combination of heavy rainfall and snowmelt. The recurrence of flash flood events during the Holocene was, however, not high enough to affect pedogenesis processes and highlight several wet regional periods during the Holocene. The Holocene period is divided into four phases of environmental evolution. Over the first half of the Holocene, a progressive stabilization of the soils present through the catchment of Lake Ledro was associated with a progressive reforestation of the area and only interrupted during the wet 8.2 event when the soil destabilization was particularly important. Lower soil erosion was recorded during the mid-Holocene climatic optimum (8000-4200 cal. yr BP) and associated with higher algal production. Between 4200 and 3100 cal. yr BP, both wetter climate and human activities within the drainage basin drastically increased soil erosion rates. Finally, from 3100 cal. yr BP to the present-day, data suggest increasing and changing human land use.

CD73-generated adenosine restricts lymphocyte migration into draining lymph nodes.

After an inflammatory stimulus, lymphocyte migration into draining lymph nodes increases dramatically to facilitate the encounter of naive T cells with Ag-loaded dendritic cells. In this study, we show that CD73 (ecto-5'-nucleotidase) plays an important role in regulating this process. CD73 produces adenosine from AMP and is expressed on high endothelial venules (HEV) and subsets of lymphocytes. Cd73(-/-) mice have normal sized lymphoid organs in the steady state, but approximately 1.5-fold larger draining lymph nodes and 2.5-fold increased rates of L-selectin-dependent lymphocyte migration from the blood through HEV compared with wild-type mice 24 h after LPS administration. Migration rates of cd73(+/+) and cd73(-/-) lymphocytes into lymph nodes of wild-type mice are equal, suggesting that it is CD73 on HEV that regulates lymphocyte migration into draining lymph nodes. The A(2B) receptor is a likely target of CD73-generated adenosine, because it is the only adenosine receptor expressed on the HEV-like cell line KOP2.16 and it is up-regulated by TNF-alpha. Furthermore, increased lymphocyte migration into draining lymph nodes of cd73(-/-) mice is largely normalized by pretreatment with the selective A(2B) receptor agonist BAY 60-6583. Adenosine receptor signaling to restrict lymphocyte migration across HEV may be an important mechanism to control the magnitude of an inflammatory response.

Post-Depositional Movement of Methanesulphonic Acid at Law Dome, Antarctica, and the Influence of Accumulation Rate

A series of ice cores from sites with different snow-accumulation rates across Law Dome, East Antarctica, was investigated for methanesulphonic acid (MSA) movement. The precipitation at these sites (up to 35 km apart) is influenced by the same air masses, the principal difference being the accumulation rate. At the low-accumulation-rate W20k site (0.17 in ice equivalent), MSA was completely relocated from the summer to winter layer. Moderate movement was observed at the intermediate-accumulation-rate site (0.7 in ice equivalent), Dome Summit South (DSS), while there was no evidence of movement at the high-accumulation-rate DE08 site (1.4 in ice equivalent). The main DSS record of MSA covered the epoch AD 1727-2000 and was used to investigate temporal post-depositional changes. Co-deposition of MSA and sea-salt ions was observed of the surface layers, outside of the main summer MSA peak, which complicates interpretation of these peaks as evidence of movement in deeper layers. A seasonal study of the 273 year DSS record revealed MSA migration predominantly from summer into autumn (in the up-core direction), but this migration was suppressed during the Tambora (1815) and unknown (1809) volcanic eruption period, and enhanced during an epoch (1770-1800) with high summer nitrate levels. A complex interaction between the gradients in nss-sulphate, nitrate and sea salts (which are influenced by accumulation rate) is believed to control the rate and extent of movement of MSA.

Trade-offs between voice and silence: a qualitative exploration of oncology staff's decisions to speak up about safety concerns

BACKGROUND Research suggests that "silence", i.e., not voicing safety concerns, is common among health care professionals (HCPs). Speaking up about patient safety is vital to avoid errors reaching the patient and thus to prevent harm and also to improve a culture of teamwork and safety. The aim of our study was to explore factors that affect oncology staff's decision to voice safety concerns or to remain silent and to describe the trade-offs they make. METHODS In a qualitative interview study with 32 doctors and nurses from 7 oncology units we investigated motivations and barriers to speaking up towards co-workers and supervisors. An inductive thematic content analysis framework was applied to the transcripts. Based on the individual experiences of participants, we conceptualize the choice to voice concerns and the trade-offs involved. RESULTS Preventing patients from serious harm constitutes a strong motivation to speaking up but competes with anticipated negative outcomes. Decisions whether and how to voice concerns involved complex considerations and trade-offs. Many respondents reflected on whether the level of risk for a patient "justifies" the costs of speaking up. Various barriers for voicing concerns were reported, e.g., damaging relationships. Contextual factors, such as the presence of patients and co-workers in the alarming situation, affect the likelihood of anticipated negative outcomes. Speaking up to well-known co-workers was described as considerably easier whereas "not knowing the actor well" increases risks and potential costs of speaking up. CONCLUSIONS While doctors and nurses felt strong obligation to prevent errors reaching individual patients, they were not engaged in voicing concerns beyond this immediacy. Our results offer in-depth insight into fears and conditions conducive of silence and voicing and can be used for educational interventions and leader reinforcement.

Periodising globalisation: Mauritian integration into the sugar commodity chain (1825-2005)

Using the case study of Mauritius, and its integration into the international sugar commodity chain, this paper shows that the analysis of commodity chains can be fruitfully employed to respond to recent calls in the field of global/world history for a periodisation of globalisation. The entry of Mauritius into the British Empire brought about a particular kind of integration of the island into the capitalist world system. Central to this integration was the production of sugar under the West Indian Sugar Protocol, with this ultimately turning Mauritius from a free port into a plantation economy. This shaped the island's economic and political practice, and brought the formation of a range of institutions that sustained a high degree of inequality among Mauritians by finding ever newer ways of conciliating socio-economic mobility with exploitation. The paper discusses Mauritian history through the framework of bilateral and multilateral trading agreements that had a significant impact on the sugar industry, and kept the island economically dependent on this single crop. This only changed when the postcolonial state succeeded in diversifying the Mauritian economy during the 1970s and 1980s.

Turning univalent stimuli bivalent: Synesthesia can cause cognitive conflict in task switching

In this study we investigated whether synesthetic color experiences have similar effects as real colors in cognitive conflict adaptation. We tested 24 synesthetes and two yoke-matched control groups in a task-switching experiment that involved regular switches between three simple decision tasks (a color decision, a form decision, and a size decision). In most of the trials the stimuli were univalent, that is, specific for each task. However, occasionally, black graphemes were presented for the size decisions and we tested whether they would trigger synesthetic color experiences and thus, turn them into bivalent stimuli. The results confirmed this expectation. We were also interested in their effect for subsequent performance (i.e., the bivalency effect). The results showed that for synesthetic colors the bivalency effect was not as pronounced as for real colors. The latter result may be related to differences between synesthetes and controls in coping with color conflict.

Reconstructing 4000 years of mass movement and tsunami history in a deep peri-Alpine lake (Lake Geneva, France-Switzerland)

The study of mass movements in lake sediments provides insights into past natural hazards at historic and prehistoric timescales. Sediments from the deep basin of Lake Geneva reveal a succession of six large-scale (volumes of 22 × 106 to 250 × 106 m3) mass-transport deposits, associated with five mass-movement events within 2600 years (4000 cal bp to 563 ad). The mass-transport deposits result from: (i) lateral slope failures (mass-transport deposit B at 3895 ± 225 cal bp and mass-transport deposits A and C at 3683 ± 128 cal bp); and (ii) Rhône delta collapses (mass-transport deposits D to G dated at 2650 ± 150 cal bp, 2185 ± 85 cal bp, 1920 ± 120 cal bp and 563 ad, respectively). Mass-transport deposits A and C were most probably triggered by an earthquake, whereas the Rhône delta collapses were likely to be due to sediment overload with a rockfall as the external trigger (mass-transport deposit G, the Tauredunum event in 563 ad known from historical records), an earthquake (mass-transport deposit E) or unknown external triggers (mass-transport deposits D and F). Independent of their origin and trigger mechanisms, numerical simulations show that all of these recorded mass-transport deposits are large enough to have generated at least metre-scale tsunamis during mass movement initiation. Since the Tauredunum event in 563 ad, two small-scale (volumes of 1 to 2 × 106 m3) mass-transport deposits (H and I) are present in the seismic record, both of which are associated with small lateral slope failures. Mass-transport deposits H and I might be related to earthquakes in Lausanne/Geneva (possibly) 1322 ad and Aigle 1584 ad, respectively. The sedimentary record of the deep basin of Lake Geneva, in combination with the historical record, show that during the past 3695 years, at least six tsunamis were generated by mass movements, indicating that the tsunami hazard in the Lake Geneva region should not be neglected, although such events are not frequent with a recurrence time of 0·0016 yr−1.

Lost in Translation: Emotion and Expression through Technology

My Thesis study was designed to bring to topic certain issues involved with CMC (computer-mediated communication.) Often we are presented with confusing or misleading situations when it comes to expressing our emotions through technological means. It is important that we are aware of certain issues such as the use of emoticons, expressing sarcasm, and the ongoing trend of Internet slang. These various aspects can create confusion in CMC, leading to a loss in translation. My survey study was designed to probe deeper into these issues by asking general questions and by analyzing sample CMC scenarios.

Learning -dependent plasticity of movement representations in the primate primary motor cortex

Primary motor cortex (M1) is involved in the production of voluntary movement and contains a complete functional representation, or map, of the skeletal musculature. This functional map can be altered by pathological experiences, such as peripheral nerve injury or stroke, by pharmacological manipulation, and by behavioral experience. The process by which experience-dependent alterations of cortical function occur is termed plasticity. In this thesis, plasticity of M1 functional organization as a consequence of behavioral experience was examined in adult primates (squirrel monkeys). Maps of movement representations were derived under anesthesia using intracortical microstimulation, whereby a microelectrode was inserted into the cortex to electrically stimulate corticospinal neurons at low current levels and evoke movements of the forelimb, principally of the hand. Movement representations were examined before and at several times after training on behavioral tasks that emphasized use of the fingers. Two behavioral tasks were utilized that dissociated the repetition of motor activity from the acquisition of motor skills. One task was easy to perform, and as such promoted repetitive motor activity without learning. The other task was more difficult, requiring the acquisition of motor skills for successful performance. Kinematic analysis indicated that monkeys used a consistent set of forelimb movements during pellet extractions. Functional mapping revealed that repetitive motor activity during the easier task did not produce plastic changes in movement representations. Instead, map plasticity, in the form of selective expansions of task-related movement representations, was only produced following skill acquisition on the difficult task. Additional studies revealed that, in general, map plasticity persisted without further training for up to three months, in parallel with the retention of task-related motor skills. Also, extensive additional training on the small well task produced further improvements in performance, and further changes in movement maps. In sum, these experiments support the following three conclusions regarding the role of M1 in motor learning. First, behaviorally-driven plasticity is learning-dependent, not activity-dependent. Second, plastic changes in M1 functional representations represent a neural correlate of acquired motor skills. Third, the persistence of map plasticity suggests that M1 is part of the neural substrate for the memory of motor skills. ^

Identidades y prácticas militantes : Una mirada en torno a los proyectos políticos. Los casos del MTD-Evita y MTD- Aníbal

Argentina, desde mediados de la década de los noventa se fue convirtiendo en escenario para movilizaciones y acciones colectivas de protesta, entre las cuales se ubicaron los movimientos de trabajadores desocupados. La relevancia de estos sucesos despertó atracción en el campo científico el cual viene desarrollando investigaciones vinculadas a la historia, las condiciones de emergencia del nuevo actor colectivo (los piqueteros) y las (re)definiciones en el juego de fuerzas que supuso su ingreso en la política nacional. No obstante, en el transcurso de los últimos años están aconteciendo ciertos procesos de cambio en el escenario político nacional que generan transformaciones dentro de las organizaciones de desocupados así como, también, abren nuevas articulaciones y (re)definiciones de sus proyectos políticos con consecuencias sustanciales en la dimensión identitaria y en el accionar militante. Por tanto, el proyecto busca analizar representaciones y prácticas políticas de los militantes de organizaciones de desocupados con el propósito de indagar en la constitución de "identidades militantes". Para ello se propone reconstruir, desde la perspectiva de los militantes, los sentidos colectivos, lógicas de acción e interacciones presentes en la constitución de los proyectos políticos de las agrupaciones políticas: MTD- Evita y MTD- Aníbal Verón de Gran La Plata.

Las Fuerzas Armadas Revolucionarias : Orígenes y desarrollo de una particular conjunción entre marxismo, peronismo y lucha armada [1960-1973]

Desde mediados de la década del cincuenta hasta la última dictadura militar, la Argentina vivió un período de gran conflictividad social y política. Particularmente desde el Cordobazo de 1969, amplios sectores de la clase trabajadora, el campo cultural, la iglesia y el movimiento estudiantil protagonizaron un intenso proceso de politización, dando lugar a un conjunto de movimientos de oposición de diverso orden. Las organizaciones armadas, al desafiar el monopolio estatal de la violencia legítima y establecer diversos lazos con el movimiento de protesta social más amplio, fueron uno de los actores destacados de ese proceso. Entre ellas, las 'Fuerzas Armadas Revolucionarias' [FAR] condensan varias problemáticas de relevancia en el período: el proceso de identificación con el peronismo de numerosos sectores de izquierda, la reivindicación de la violencia como forma de intervención política y la opción por la lucha armada como modalidad específica de ponerla en práctica. Pese a su importancia, hasta el momento no se había realizado ningún trabajo académico específico sobre esta organización. La presente tesis analiza los orígenes y el desarrollo de las FAR considerando el período que va desde los primeros sesenta, en que comenzaron a perfilarse sus grupos fundadores, hasta las elecciones presidenciales del 11 de marzo de 1973. Desde entonces no sólo cambia notablemente la dinámica política nacional, sino que la realidad de la organización ya está signada por el proceso de fusión con Montoneros, que fue anunciada de modo público en octubre de ese año. El problema de investigación articula dos ejes analíticos. Por un lado, el proceso de identificación de las FAR con el peronismo, cuyos antecedentes se remontan a las sucesivas reinterpretaciones realizadas por sus grupos fundadores sobre el fenómeno. El segundo, con su dinámica de funcionamiento como organización político-militar de actuación nacional y urbana, gestada al calor de los cambios de estrategias que se plantearon aquellos grupos fundadores para lograr el proceso de liberación nacional y social que impulsaban. Ambas líneas de análisis implican, además, adentrarse en los modos en que la organización concibió sus vínculos con sectores más amplios de la sociedad, particularmente con aquellos que buscaba movilizar. Para realizar la tesis se apeló a una estrategia metodológica cualitativa. Se relevaron fuentes escritas [diarios y revistas de alcance nacional, documentos de las FAR y de otras organizaciones con que se vincularon] y se realizaron entrevistas semiestructuradas a ex-miembros de la organización

Psychosocial construction of time and social change

This paper analyzes the psychosocial construction of the conceptions of time and social change, and their relation with the notion of progress set up by modernity as well as their contradictory aspects, considering their historicity as psychosocial and social phenomena. The social construction of the notion of time is discussed; it responds to social organization forms, thus turning the social changes into historical and temporal landmarks. The association between social changes and social movements is argued and the concept of progress is deconstructed. Finally, the importance of the idea of movement in the construction of time, change and progress concepts is pointed out; it is also explained how modernity imbued such notions with direction and goals, in the direction of an arrow, according to the prevailing interests, while modeling them in its own image and likeness.

Las Fuerzas Armadas Revolucionarias : Orígenes y desarrollo de una particular conjunción entre marxismo, peronismo y lucha armada [1960-1973]

Desde mediados de la década del cincuenta hasta la última dictadura militar, la Argentina vivió un período de gran conflictividad social y política. Particularmente desde el Cordobazo de 1969, amplios sectores de la clase trabajadora, el campo cultural, la iglesia y el movimiento estudiantil protagonizaron un intenso proceso de politización, dando lugar a un conjunto de movimientos de oposición de diverso orden. Las organizaciones armadas, al desafiar el monopolio estatal de la violencia legítima y establecer diversos lazos con el movimiento de protesta social más amplio, fueron uno de los actores destacados de ese proceso. Entre ellas, las 'Fuerzas Armadas Revolucionarias' [FAR] condensan varias problemáticas de relevancia en el período: el proceso de identificación con el peronismo de numerosos sectores de izquierda, la reivindicación de la violencia como forma de intervención política y la opción por la lucha armada como modalidad específica de ponerla en práctica. Pese a su importancia, hasta el momento no se había realizado ningún trabajo académico específico sobre esta organización. La presente tesis analiza los orígenes y el desarrollo de las FAR considerando el período que va desde los primeros sesenta, en que comenzaron a perfilarse sus grupos fundadores, hasta las elecciones presidenciales del 11 de marzo de 1973. Desde entonces no sólo cambia notablemente la dinámica política nacional, sino que la realidad de la organización ya está signada por el proceso de fusión con Montoneros, que fue anunciada de modo público en octubre de ese año. El problema de investigación articula dos ejes analíticos. Por un lado, el proceso de identificación de las FAR con el peronismo, cuyos antecedentes se remontan a las sucesivas reinterpretaciones realizadas por sus grupos fundadores sobre el fenómeno. El segundo, con su dinámica de funcionamiento como organización político-militar de actuación nacional y urbana, gestada al calor de los cambios de estrategias que se plantearon aquellos grupos fundadores para lograr el proceso de liberación nacional y social que impulsaban. Ambas líneas de análisis implican, además, adentrarse en los modos en que la organización concibió sus vínculos con sectores más amplios de la sociedad, particularmente con aquellos que buscaba movilizar. Para realizar la tesis se apeló a una estrategia metodológica cualitativa. Se relevaron fuentes escritas [diarios y revistas de alcance nacional, documentos de las FAR y de otras organizaciones con que se vincularon] y se realizaron entrevistas semiestructuradas a ex-miembros de la organización

Psychosocial construction of time and social change

This paper analyzes the psychosocial construction of the conceptions of time and social change, and their relation with the notion of progress set up by modernity as well as their contradictory aspects, considering their historicity as psychosocial and social phenomena. The social construction of the notion of time is discussed; it responds to social organization forms, thus turning the social changes into historical and temporal landmarks. The association between social changes and social movements is argued and the concept of progress is deconstructed. Finally, the importance of the idea of movement in the construction of time, change and progress concepts is pointed out; it is also explained how modernity imbued such notions with direction and goals, in the direction of an arrow, according to the prevailing interests, while modeling them in its own image and likeness.

Identidades y prácticas militantes : Una mirada en torno a los proyectos políticos. Los casos del MTD-Evita y MTD- Aníbal

Argentina, desde mediados de la década de los noventa se fue convirtiendo en escenario para movilizaciones y acciones colectivas de protesta, entre las cuales se ubicaron los movimientos de trabajadores desocupados. La relevancia de estos sucesos despertó atracción en el campo científico el cual viene desarrollando investigaciones vinculadas a la historia, las condiciones de emergencia del nuevo actor colectivo (los piqueteros) y las (re)definiciones en el juego de fuerzas que supuso su ingreso en la política nacional. No obstante, en el transcurso de los últimos años están aconteciendo ciertos procesos de cambio en el escenario político nacional que generan transformaciones dentro de las organizaciones de desocupados así como, también, abren nuevas articulaciones y (re)definiciones de sus proyectos políticos con consecuencias sustanciales en la dimensión identitaria y en el accionar militante. Por tanto, el proyecto busca analizar representaciones y prácticas políticas de los militantes de organizaciones de desocupados con el propósito de indagar en la constitución de "identidades militantes". Para ello se propone reconstruir, desde la perspectiva de los militantes, los sentidos colectivos, lógicas de acción e interacciones presentes en la constitución de los proyectos políticos de las agrupaciones políticas: MTD- Evita y MTD- Aníbal Verón de Gran La Plata.