Collecção das Leis do Brazil de 1813

Parte 1 - Cartas de Lei, Alvarás, Decretos e Cartas Régias

Collecção das Leis do Brazil de 1814

Parte 1 - Cartas de Lei, Alvarás, Decretos e Cartas Régias

Human Papillomavirus (HPV) genotype 18 variants in patients with clinical manifestations of HPV related infections in Bilbao, Spain

Background:Human papillomavirus (HPV) variants differ in their biological and chemical properties, and therefore, may present differences in pathogenicity. Most authors classified variants based on the phylogenetic analysis of L1 region. Nevertheless, recombination in HPV samples is becoming a usual finding and thus, characterizing genetic variability in other regions should be essential. Objectives:We aimed to characterize the genetic variability of HPV 18 in 5 genomic regions: E6, E7, E4, L1 and the Upstream Regulatory Region (URR), working with both single infection and multiple HPV infection samples. Furthermore, we aimed to assess the prevalence of HPV 18 variants in our region and look for possible existence of recombination as well as analyze the relationship between these variants and the type of lesion. Methods: From 2007 to 2010, Clinical Microbiology and Infection Control Department analyzed 44 samples which were positive for HPV 18. Genetic variability was determined in PCR products and variants were assigned to European, Asian-amerindian or African lineage. Recombination and association of variants with different types of lesion was studied. Results: Genetic analysis of the regions revealed a total of 56 nucleotide variations. European, African and Asian-amerindian variants were found in 25/44 (56.8%), 10/44 (22.7%) and 5/44 (11.4%) samples, respectively. We detected the presence of recombinant variants in 2/44 (4.5%) cases. Samples taken from high-grade squamous intraepithelial lesions (H-SIL) only presented variants with specific-african substitutions. Conclusions: Multiple HPV infection, non-european HPV variants prevalence and existence of recombination are considered risk factors for HPV persistence and progression of intraepithelial abnormalities, and therefore, should be taken into consideration in order to help to design and optimize diagnostics protocols as well as improve epidemiologic studies. Our study is one of the few studies in Spain which analyses the genetic variability of HPV18 and we showed the importance of characterizing more than one genomic region in order to detect recombination and classify HPV variants properly

Carta que ao Illustre Deputado em Cortes o Senhor Luiz Nicolao Fagundes Varella, escreveo hum zellozo patriota em 14 de dezembro de 1821, dada á luz por José Alves Ribeiro de Mendonça

Diccionario Bibliographico Portuguez / Innocencio Francisco da Silva, 1860. v. 4, p. 219.

Officio, e documentos dirigidos às Cortes Geraes, Extraordinarias, e Constituintes da Nação Portugueza, pela Junta Provisoria do Governo da Provincia de Pernambuco

Referência: Biblioteca Nacional de Portugal- Catálogo On-line.

Officios, e mais documentos dirigidos ao Governo pelo Ministerio do Rio de Janeiro : com data de 17 de fevereiro e 21 de março deste anno, e tambem a repesentação dirigida às Cortes pela Camara do Rio de Janeiro

Referência : Biblioteca Nacional de Portugal- Catálogo On-line.

Cartas e documentos dirigidos a Sua Magestade o Senhor D. João VI pelo Principe Real o Senhor D. Pedro de Alcântara : e que forão presentes às Cortes em a Sessão de 28 de septembro de 1822

A carta na qual Dom Pedro comunica a Independência do Brasil é datada de 26 de setembro de 1822 e contém a ata da sua aclamação como Imperador Constitucional e Defensor Perpétuo do Brasil.

Copia do recurso, e addendo ao mesmo, que as soberanas Cortes de Portugal dirigem mil e cincoenta e dous constitucionaes da notavel, e sempre fiel cidade da Bahia

Referência : Biblioteca Nacional de Portugal - Catálogo On-line.

Officios e documentos dirigidos às Cortes Geraes extraordinarias e constituintes da Nação Portugueza, dois pela Junta Provisoria do Governo da Provincia das Alagoas com as datas de 6 de maio, e de 2 de junho deste anno ; e dois pela Junta Provisoria do Governo da Provincia do Grão Pará com as datas de 8 de junho, e 8 de julho do mesmo anno :estes officios, sendo presentes as Cortes em a Sessão de 17 de agosto, forão ouvidos com especial agrado

As províncias apresentaram ao Príncipe Regente ofícios e documentos que, remetidos para Lisboa e publicados a mando das Cortes, permitem também acompanhar o processo.

Participação, e documentos dirigidos ao governo pelo general commandante da tropa expedicionaria, que existia na provincia do Rio de Janeiro, chegando a Lisboa e remettidos pelo governo ás Cortes Geraes, Extraordinarias, e Constituintes da Nação Portugueza

Com: Cartas, e mais peças officiaes dirigidas a S. Magestade, o senhor D. João VI pelo principe real, o senhor D. Pedro de Alcantara -- Cartas, e mais peças officiaes dirigidas a sua magestade, o senhor D. João VI pelo principe real, o senhor D. Pedro de Alcantara e junctamente os officios e documentos, que o general commandante da tropa expedicionaria existente na provincia do Rio de Janeiro tinha dirigido ao governo -- Cartas dirigidas a S. Magestade, o senhor D. João VI pelo principe real o senhor D. Pedro de Alcantara.

Genetics of Type III Bartter Syndrome in Spain, Proposed Diagnostic Algorithm

9 p.

Dynamics of Streptococcus pneumoniae Serotypes Causing Acute Otitis Media Isolated from Children with Spontaneous Middle-Ear Drainage over a 12-Year Period (1999–2010) in a Region of Northern Spain

10 p.

First occurrence of Mosasauridae (Squamata) in the Maastrichtian (latest Cretaceous) of Alicante (Valencia Community, Eastern Spain)

8 p.

Cost effectiveness of a combination of instruments for global warming: a quantitative approach for Spain

Climate change is an important environmental problem and one whose economic implications are many and varied. This paper starts with the presumption that mitigation of greenhouse gases is a necessary policy that has to be designed in a cost effective way. It is well known that market instruments are the best option for cost effectiveness. But the discussion regarding which of the various market instruments should be used, how they may interact and what combinations of policies should be implemented is still open and very lively. In this paper we propose a combination of instruments: the marketable emission permits already in place in Europe for major economic sectors and a CO(2) tax for economic sectors not included in the emissions permit scheme. The study uses an applied general equilibrium model for the Spanish economy to compute the results obtained with the new mix of instruments proposed. As the combination of the market for emission permits and the CO(2) tax admits different possibilities that depend on how the mitigation is distributed among the economic sectors, we concentrate on four possibilities: cost-effective, equalitarian, proportional to emissions, and proportional to output distributions. Other alternatives to the CO(2) tax are also analysed (tax on energy, on oil and on electricity). Our findings suggest that careful, well designed policies are needed as any deviation imposes significant additional costs that increase more than proportionally to the level of emissions reduction targeted by the EU.