Digital Preservation and Web Access to the Konkoly Observatory Schmidt Telescope Plate Archive

ACM Computing Classification System (1998): J.2.

Einführung einer institutionellen Forschungsdateninfrastruktur an der Helmut-Schmidt-Universität

Die vorliegende Bachelorarbeit untersucht den zur Einführung einer institutionellen Forschungsdateninfrastruktur zu berücksichtigenden Handlungsrahmen an der Helmut-Schmidt-Universität/ Universität der Bundeswehr Hamburg (HSU/ UniBw H) und gibt unter besonderer Berücksichtigung möglicher Aufgabenfelder der Universitätsbibliothek allgemeine Handlungsempfehlungen für deren Implementierung. Da sich die Arbeit sowohl an die Verantwortlichen zur Einführung einer Forschungsdateninfrastruktur an der HSU/ UniBw H als auch an Interessierte der akademischen Gemeinschaft richtet, werden die zum besseren Verständnis besonders relevanten Begriffe zunächst herausgestellt. Auf der Grundlage aktueller Forschungsliteratur und verfügbarer Praxiserfahrung anderer Universitäten wurde mittels Webseitenanalyse und der Auswertung von Fragebögen eine gesamtheitliche Beschreibung für die Implementierung einer institutionellen Forschungsdateninfrastruktur zum Abgleich mit der Ausgangssituation an der HSU/ UniBw H erstellt. Die Arbeit verdeutlicht in den daraus abgeleiteten Handlungsempfehlungen den zu berücksichtigenden allgemeinen Handlungsrahmen in seiner Komplexität und zeigt vor allem diesbezügliche Aufgabenfelder der Universitätsbibliothek von der Initiierung bis zum Abschluss der Implementierung auf. Im Wesentlichen wird hierbei herausgestellt, dass die Universitätsbibliothek als klassische Gedächtnisorganisation und zentraler Informationsdienstleister ihre Kompetenzen besonders bei der Entwicklung und Verwirklichung des Forschungsdatenmanagements sinnvoll einbringen und zukunftsorientiert erweitern kann und sollte. Auslegungsbestimmend ist die von der Universitätsleitung festzulegende Ziel- und Zweckbestimmung der institutionellen Forschungsdateninfrastruktur. Diese dient dem Forschungsdatenmanagement zur Skalierung und Bestimmung von Umfang, Komplexität und Anforderungen an die potentiellen Aufgabenbereiche insbesondere der Universitätsbibliothek. Somit leistet diese Bachelorarbeit einen grundlegenden Beitrag zur weiteren Strukturierung und Konkretisierung der initiatorischen Überlegungen der Universitätsbibliotheksleitung zu den Möglichkeiten der Einführung einer institutionellen Forschungsdateninfrastruktur an der HSU/ UniBw H.

Angelika Schmidt-Koddenberg / Simone Zorn: Zukunft gesucht! Berufs-und Studienorientierung in der Sek. II. Berlin u.a.: Budrich 2011 [Rezension]

Rezension von: Angelika Schmidt-Koddenberg / Simone Zorn: Zukunft gesucht! Berufs-und Studienorientierung in der Sek. II, Berlin u.a.: Budrich 2011 (183 S.; ISBN 978-3-8664-9381-0)

Inge Hansen-Schaberg: Minna Specht - Eine Sozialistin in der Landerziehungsheimbewegung (1918 bis 1951). Untersuchung zur pädagogischen Biographie einer Reformpädagogin. (Studien zur Bildungsreform. Bd. 22). Frankfurt a.M./Bern: Lang 1992 [Rezension]

Rezension von: Inge Hansen-Schaberg: Minna Specht - Eine Sozialistin in der Landerziehungsheimbewegung (1918 bis 1951). Untersuchung zur pädagogischen Biographie einer Reformpädagogin. (Studien zur Bildungsreform. Bd. 22). Frankfurt a.M./Bern: Lang 1992, 406 S.

Melhoria da Atenção ao Pré-Natal e Puerpério na UBS/ESF Dr. Willy Belmiro Schmidt, Em Santo Ângelo/RS.

O trabalho se constitui em uma intervenção a qual previa a qualificação do Pré-Natal e puerpério prestado a gestantes e puérperas residentes na área de abrangência da ESF Dr. Willy Belmiro Schmidt, Bairro Subuski, em Santo Ângelo – RS. Para isto foi realizado um projeto com o objetivo geral de melhorar a atenção ao pré-natal e puerpério da ESF Dr. Willy Belmiro Schmidt, Bairro Subuski, Santo Ângelo, RS.A intervenção foi realizada no período de fevereiro a maio de 2015, mas totalizando 3 meses de intervenção, pois houve férias.A intervenção teve sua relevância justificada, pois é fundamental para a saúde materna e neonatal uma atenção ao pré-natal e puerperal de qualidade e humanizada. O cuidado com as gestantes e puérperas incluiu ações de prevenção de doenças e promoção da saúde, além de diagnóstico e tratamento precoces das patologias que podem ocorrer nesse período. Para alcançar os objetivos foram realizadas ações nos quatro eixos pedagógicos do curso: monitoramento e avaliação, organização e gestão do serviço, engajamento público e qualificação da prática clínica. Antes do projeto, a assistência ao pré-natal era bastante precária, tanto em relação ao registro das informações, bem como em relação a cobertura e qualidade do atendimento. Desta forma, após a intervenção obtivemos como principais resultados 91% das gestantes da área cadastradas no programa, 100% das puérperas com consulta até o 42º após o parto e 88% das gestantes com consulta odontológica. As ações propostas e desenvolvidas nesta intervenção se constituem de ações simples, mas de grande relevância para a qualificação da assistência ao pré-natal e puerpério, e contribuíram para a melhoria dos atendimentos dispensados as mulheres gestantes e puérperas atendidas pela equipe ESF.

Phytochemical Markers Of Different Types Of Red Propolis.

Propolis is a resin that bees collect from different plant sources and use in the defense of the bee community. The intricate composition of propolis varies depending on plant sources from different geographic regions and many types have been reported. Red coloured propolis found in several states in Brazil and in other countries has known antimicrobial and antioxidant activity. Different analytical methods have been applied to studies regarding the chemical composition and plant origins of red propolis. In this study samples of red propolis from different regions have been characterised using direct infusion electrospray ionisation mass spectrometry (ESI(-)-MS) fingerprinting. Data from the fingerprints was extracted and analysed by multivariate analysis to group the samples according to their composition and marker compounds. Despite similar colour, the red coloured propolis samples were divided into three groups due to contrasting chemical composition, confirming the need to properly characterise the chemical composition of propolis.

Equity Of Access To Pap Smears: Population-based Study In Campinas, São Paulo, Brazil.

To determine the prevalence of the Papanicolaou exam among women aged 20 to 59 years in the city of Campinas (state of São Paulo, Brazil) and to analyze associations between this test and affiliation to private health insurance plans as well as socioeconomic/demographic variables and health-related behavior. To do so, a population-based, cross-sectional study was carried out. Statistical analyses took the study design into account. Despite the significant socioeconomic differences between women with and without private health plans, no differences between these groups were found regarding having been submitted to the Papanicolaou test. In fact no differences were found as to socioeconomic and health variables analyzed. Among all variables analyzed, only marital status was significantly associated with having undergone the test. The Brazilian public health system accounted for 55.7% of the exams. The present findings indicate social equity in the city of Campinas regarding the preventive exam for cervical cancer in the age group studied.

Direct And Non-destructive Proof Of Authenticity For The 2nd Generation Of Brazilian Real Banknotes Via Easy Ambient Sonic Spray Ionization Mass Spectrometry.

Using a desorption/ionization technique, easy ambient sonic-spray ionization coupled to mass spectrometry (EASI-MS), documents related to the 2nd generation of Brazilian Real currency (R$) were screened in the positive ion mode for authenticity based on chemical profiles obtained directly from the banknote surface. Characteristic profiles were observed for authentic, seized suspect counterfeit and counterfeited homemade banknotes from inkjet and laserjet printers. The chemicals in the authentic banknotes' surface were detected via a few minor sets of ions, namely from the plasticizers bis(2-ethylhexyl)phthalate (DEHP) and dibutyl phthalate (DBP), most likely related to the official offset printing process, and other common quaternary ammonium cations, presenting a similar chemical profile to 1st-generation R$. The seized suspect counterfeit banknotes, however, displayed abundant diagnostic ions in the m/z 400-800 range due to the presence of oligomers. High-accuracy FT-ICR MS analysis enabled molecular formula assignment for each ion. The ions were separated by 44 m/z, which enabled their characterization as Surfynol® 4XX (S4XX, XX=40, 65, and 85), wherein increasing XX values indicate increasing amounts of ethoxylation on a backbone of 2,4,7,9-tetramethyl-5-decyne-4,7-diol (Surfynol® 104). Sodiated triethylene glycol monobutyl ether (TBG) of m/z 229 (C10H22O4Na) was also identified in the seized counterfeit banknotes via EASI(+) FT-ICR MS. Surfynol® and TBG are constituents of inks used for inkjet printing.

A Comparison Between Characterization And Biological Properties Of Brazilian Fresh And Aged Propolis.

As propolis is a highly valued bee product, we aimed to verify the quality of aged propolis, investigating their phenolic and flavonoid composition, levels of toxic metals, radical scavenging and antimicrobial activities. Samples of fresh and aged propolis of six different beekeepers, from the same geographical location, were investigated in terms of their phenolic and flavonoid composition and levels of Pb, Cd, and Cr, as well as radical scavenging and antimicrobial activities. The two groups of propolis had similar qualitative composition by HPLC-PDA and ESI(-)-MS. Fresh propolis and aged propolis show no differences when average values of extraction yield, flavonoids, EC50, or MIC were compared and both types of propolis showed good antimicrobial activity at low concentrations. Only levels of phenolic compounds were higher in fresh propolis. The propolis samples considered in this study, aged or fresh, had similar qualitative composition, although they were collected in different periods. Samples only differed in their levels of total phenolic content. Moreover, aged propolis conserves significant radical scavenging and antimicrobial properties. We suggest that aged propolis should not be discarded but explored for alternative applications.

Antitumor Activity Of Irradiated Riboflavin On Human Renal Carcinoma Cell Line 786-o.

Riboflavin (vitamin B2) is a precursor for coenzymes involved in energy production, biosynthesis, detoxification, and electron scavenging. Previously, we demonstrated that irradiated riboflavin (IR) has potential antitumoral effects against human leukemia cells (HL60), human prostate cancer cells (PC3), and mouse melanoma cells (B16F10) through a common mechanism that leads to apoptosis. Hence, we here investigated the effect of IR on 786-O cells, a known model cell line for clear cell renal cell carcinoma (CCRCC), which is characterized by high-risk metastasis and chemotherapy resistance. IR also induced cell death in 786-O cells by apoptosis, which was not prevented by antioxidant agents. IR treatment was characterized by downregulation of Fas ligand (TNF superfamily, member 6)/Fas (TNF receptor superfamily member 6) (FasL/Fas) and tumor necrosis factor receptor superfamily, member 1a (TNFR1)/TNFRSF1A-associated via death domain (TRADD)/TNF receptor-associated factor 2 (TRAF) signaling pathways (the extrinsic apoptosis pathway), while the intrinsic apoptotic pathway was upregulated, as observed by an elevated Bcl-2 associated x protein/B-cell CLL/lymphoma 2 (Bax/Bcl-2) ratio, reduced cellular inhibitor of apoptosis 1 (c-IAP1) expression, and increased expression of apoptosis-inducing factor (AIF). The observed cell death was caspase-dependent as proven by caspase 3 activation and poly(ADP-ribose) polymerase-1 (PARP) cleavage. IR-induced cell death was also associated with downregulation of v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homologue (avian)/protein serine/threonine kinase B/extracellular signal-regulated protein kinase 1/2 (Src/AKT/ERK1/2) pathway and activation of p38 MAP kinase (p38) and Jun-amino-terminal kinase (JNK). Interestingly, IR treatment leads to inhibition of matrix metalloproteinase-2 (MMP-2) activity and reduced expression of renal cancer aggressiveness markers caveolin-1, low molecular weight phosphotyrosine protein phosphatase (LMWPTP), and kinase insert domain receptor (a type III receptor tyrosine kinase) (VEGFR-2). Together, these results show the potential of IR for treating cancer.