Ernst Gottschalk and his mother Henriette Gottschalk nee Rothschild with sheitl.

Photograph owned by Yael Arnold, Waldstetten; copied by Thomas Krakauer

Portrait of Ernst Gottschalk (seated second row center) with eight unidentified soldiers; Rendsburg, Germany. Military Portraits groups

Morgen hat Reserve Ruh / Auf Wiedersehen / Beste Gruesse; postcard signer Gottschalk; addressee: L Nurzinsky, Altona-Othmarschen, Aidikes Str.

Postcard distributed by M. Molling & Co. to commemorate the 100th anniversary of Friedrich Schiller's death; Hannover, Germany. Advertisements

Addressed to Therese Gottschalk nee Molling, postmarked 25 April 1905 and mailed from Hannover to Hildesheim, most likely while Therese was visiting her Meyerhof grandparents

Tombstone of Meta Levy nee Daniel; Strangriede Cemetery; Hannover Cemeteries Tombs

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Silhouette of Ernst Gottschalk Artworks

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Negligible evidence for regional genetic population structure for two shark species Rhizoprionodon acutus (Rüppell, 1837) and Sphyrna lewini (Griffith & Smith, 1834) with contrasting biology

Biodiversity of sharks in the tropical Indo-Pacific is high, but species-specific information to assist sustainable resource exploitation is scarce. The null hypothesis of population genetic homogeneity was tested for scalloped hammerhead shark (Sphyrna lewini, n = 237) and the milk shark (Rhizoprionodon acutus, n = 207) from northern and eastern Australia, using nuclear (S. lewini, eight microsatellite loci; R. acutus, six loci) and mitochondrial gene markers (873 base pairs of NADH dehydrogenase subunit 4). We were unable to reject genetic homogeneity for S. lewini, which was as expected based on previous studies of this species. Less expected were similar results for R. acutus, which is more benthic and less vagile than S. lewini. These features are probably driving the genetic break found between Australian and central Indonesian R. acutus (F-statistics; mtDNA, 0.751–0.903, respectively; microsatellite loci, 0.038–0.047 respectively). Our results support the spatially homogeneous monitoring and management plan for shark species in Queensland, Australia.

Tombstone of Meta Levy nee Daniel; Strangriede Cemetery; Hannover Cemeteries Tombs

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Friedrich Bergammer (Fritz Glueckselig) standing in the doorway of the gallery store M. Glueckselig & Son; 108 East 57th Street, New York Portraits Men

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Portrait of Friedrich Bergammer (Fritz Glueckselig) Portraits Men

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Portrait of Ernst Gottschalk with his wife Louise "Isa" nee Rosenthal; Welwyn Garden City, England.

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Studio portrait of Joseph Molling and business partner Ernst Joachim (?); Hannover, Germany.

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Henriette Gottschalk nee Rothschild with her sons Ernst (on left) and Fritz Gottschalk in her garden.

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Friedrich Unger; Zurich.

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Grete and Ernst Glasner (seated center); Danubius, Bratislava.

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New genetic loci link adipose and insulin biology to body fat distribution

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10−8). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms.