910 resultados para Perry, John.


Relevância:

20.00% 20.00%

Publicador:

Resumo:

Audit report on the City of Perry, Iowa for the year ended June 30, 2013

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Audit report on the Perry Municipal Waterworks, Perry, Iowa for the year ended June 30, 2013

Relevância:

20.00% 20.00%

Publicador:

Resumo:

To identify common variants influencing body mass index (BMI), we analyzed genome-wide association data from 16,876 individuals of European descent. After previously reported variants in FTO, the strongest association signal (rs17782313, P = 2.9 x 10(-6)) mapped 188 kb downstream of MC4R (melanocortin-4 receptor), mutations of which are the leading cause of monogenic severe childhood-onset obesity. We confirmed the BMI association in 60,352 adults (per-allele effect = 0.05 Z-score units; P = 2.8 x 10(-15)) and 5,988 children aged 7-11 (0.13 Z-score units; P = 1.5 x 10(-8)). In case-control analyses (n = 10,583), the odds for severe childhood obesity reached 1.30 (P = 8.0 x 10(-11)). Furthermore, we observed overtransmission of the risk allele to obese offspring in 660 families (P (pedigree disequilibrium test average; PDT-avg) = 2.4 x 10(-4)). The SNP location and patterns of phenotypic associations are consistent with effects mediated through altered MC4R function. Our findings establish that common variants near MC4R influence fat mass, weight and obesity risk at the population level and reinforce the need for large-scale data integration to identify variants influencing continuous biomedical traits.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Annual report of the John Pappajohn Entrepreneurial Center at the University of Iowa.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Annual report of the John Pappajohn Entrepreneurial Center at the University of Iowa.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Annual report of the John Pappajohn Entrepreneurial Center at the University of Iowa.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

A water-surface-elevation profile and peak discharges for the flood of May 19, 1990, along Perry Creek in Plymouth and Woodbury Counties, Iowa, are presented in this report. The peak discharge for the May 19, 1990, flood on Perry Creek at 38th Street, Sioux City (06600000) is the second largest flood-peak discharge recorded at the streamflow-gaging station for the period 1939-95. The peak discharge for May 19, 1990, of 8,670 cubic feet per second, is approximately equal to the 35-year recurrence-interval discharge. The report provides information on flood stages and discharges and floodflow frequencies for streamflow- gaging stations in the Perry Creek Basin using flood information collected during 1939-95. Information on temporary bench marks and reference points established in the Perry Creek Basin during 1990-93 is also included in the report. A flood history describes rainfall conditions for the three largest floods that occurred during 1939-95 (July 1944, September 1949, and May 1990).

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Audit report on the Perry Municipal Waterworks, Perry, Iowa for the year ended June 30, 2014

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Audit report on the City of Perry, Iowa for the year ended June 30, 2014

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Vastine Sami Pihlströmin kirjoitukseen Tieteessä tapahtuu-lehden numerossa 4/2000

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Audit report on the Perry Municipal Waterworks, Perry, Iowa for the year ended June 30, 2015