Technology News, July, 1897

Technology News is a newsletter produced by the Iowa Department of Transportation to provide information to the transportation specialist in Iowa's cities and counties. Technology News is one of CTRE's primary avenues for exchanging transportation-related information with local agencies. The bimonthly newsletter gives an up-to-date look to the up-to-date information our 2,500+ readers have grown to expect.

Technology News, November, 1897

Technology News is a newsletter produced by the Iowa Department of Transportation to provide information to the transportation specialist in Iowa's cities and counties. Technology News is one of CTRE's primary avenues for exchanging transportation-related information with local agencies. The bimonthly newsletter gives an up-to-date look to the up-to-date information our 2,500+ readers have grown to expect.

Role of homer 1 proteins in the calcium signaling pathway(s) underlying exo-endocytosis processes of glutamatergic slmvs in astrocytes

The discovery that astrocytes possess a nonelectrical form of excitability (calcium excitability) that leads to the release of chemical transmitters, an activity called gliotransmission, indicates that these cells may have additional important roles in brain function. Elucidating the stimulussecretion coupling leading to the exocytic release of chemical transmitters (such as glutamate, Bezzi et al., Nature Neurosci, 2004) may therefore clarify i) whether astrocytes represent in full a new class of secretory cells in the brain and ii) whether they can participate to the fast brain signaling in the brain. We have recently discovered the existence in astrocytes of functional sub-membrane microdomains of calcium release from the internal stores in response to mGluR5 activation (Marchaland et al., J of Neurosci., 2008). Such sub-plasma membrane calcium microdomains control exocytosis of astrocytic glutamate signaling to neurons. Homer proteins are scaffold proteins controlling calcium signaling in different cellular microdomains, including dendritic spines in neurons (Sala et al., J of Neurosci., 2005). Thus, similarly to dendritic pines, Homer1 could be implicated in the coupling between astrocytic mGluR5 and IP3Rs on the ER. Here, by using a recently developed approach for studying vesicle recycling dynamics at synapses (Voglmaier et al., Neuron, 2006; Balaji and Ryan, PNAS, 2007) combined with epifluorescence and total internal reflection fluorescence (TIRF) imaging, we investigated the involvement of Homer1 proteins in the calcium dependent stimulus-secretion coupling leading glutamate exocytosis of synaptic-like microvesicles (SLMVs) in astrocytes.

Discours prononcé par M. Jean-Robert Deschamps-Dumesnil, curé de Saint-Martin...le 23 janvier 1791, pour la prestation du serment, conformément au décret concernant la constitution civile du clergé ([Reprod.])

[Discours. 1791-01-23. Saint-Martin]

22-10-19, congrès de l'U.V.F. [Union vélocipédique de France, debout, de gauche à droite, Alfred Riguelle, René Mathis, Van Steenbrugghe, Georges Duchesne, et assis, Louis Josset, Georges Chollet, Léon Breton, Schrader, Ernest Delamarre, Tristan Bernard, Claude Martin] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 56597

22-10-19, congrès de l'U.V.F.[Union vélocipédique de France, debout, de gauche à droite, Alfred] Riguelle, [René] Mathis, Van Steenbrugghe, [Georges] Duchesne, [et assis, Louis] Josset, [Georges] Chollet, [Léon] Breton, Schrader, [Ernest] Delamarre, Tristan Bernard, [Claude] Martin : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 56598

Discours de M. Surget, curé de St-Martin à ses paroissiens, dans lequel il expose les motifs qui l'ont déterminé à prêter son serment ([Reprod.])

Collection : Les archives de la Révolution française ; 8.484