Anuario Científico y Tecnológico IMARPE 2012

Reúne información sobre los Programas de investigación y actividades/proyectos realizados por las Direcciones de Investigación de la Sede Central y las diez Sedes Descentralizadas del IMARPE. Se destacan los resultados logrados en base a la Matriz de Actividades y Proyectos de Investigaciones Científicas y Tecnológicas durante el año 2012.

Anuario Científico y Tecnológico IMARPE 2013

El Anuario Científico Tecnológico IMARPE, reúne información sobre las actividades científicas y tecnológicas realizadas durante el año 2013, por las cinco Direcciones Generales de Investigación y por las diez Sedes Descentralizadas del IMARPE. Se destacan resultados relevantes referidos a los Programas de Investigación, sus Líneas de Investigación y los Objetivos Específicos consignados en la Matriz de Actividades y Proyectos de Investigación Científica y Tecnológica del año 2013.

Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium.

OBJECTIVES: To investigate whether associations of smoking with depression and anxiety are likely to be causal, using a Mendelian randomisation approach. DESIGN: Mendelian randomisation meta-analyses using a genetic variant (rs16969968/rs1051730) as a proxy for smoking heaviness, and observational meta-analyses of the associations of smoking status and smoking heaviness with depression, anxiety and psychological distress. PARTICIPANTS: Current, former and never smokers of European ancestry aged ≥16 years from 25 studies in the Consortium for Causal Analysis Research in Tobacco and Alcohol (CARTA). PRIMARY OUTCOME MEASURES: Binary definitions of depression, anxiety and psychological distress assessed by clinical interview, symptom scales or self-reported recall of clinician diagnosis. RESULTS: The analytic sample included up to 58 176 never smokers, 37 428 former smokers and 32 028 current smokers (total N=127 632). In observational analyses, current smokers had 1.85 times greater odds of depression (95% CI 1.65 to 2.07), 1.71 times greater odds of anxiety (95% CI 1.54 to 1.90) and 1.69 times greater odds of psychological distress (95% CI 1.56 to 1.83) than never smokers. Former smokers also had greater odds of depression, anxiety and psychological distress than never smokers. There was evidence for positive associations of smoking heaviness with depression, anxiety and psychological distress (ORs per cigarette per day: 1.03 (95% CI 1.02 to 1.04), 1.03 (95% CI 1.02 to 1.04) and 1.02 (95% CI 1.02 to 1.03) respectively). In Mendelian randomisation analyses, there was no strong evidence that the minor allele of rs16969968/rs1051730 was associated with depression (OR=1.00, 95% CI 0.95 to 1.05), anxiety (OR=1.02, 95% CI 0.97 to 1.07) or psychological distress (OR=1.02, 95% CI 0.98 to 1.06) in current smokers. Results were similar for former smokers. CONCLUSIONS: Findings from Mendelian randomisation analyses do not support a causal role of smoking heaviness in the development of depression and anxiety.

Anuario Científico Tecnológico IMARPE 2014

El Anuario Científico Tecnológico IMARPE, reúne información sobre programas de investigación y actividades y proyectos realizados por las Direcciones de Investigación de la Sede Central y las diez sedes descentralizadas del IMARPE, Se destacan los resultados logrados en base a la Matriz de Actividades y proyectos de Investigaciones Científicas y Tecnológicas durante el 2014.

Mielen rajamailla

Teuvo Laitila

Filaroides osleri -madon aiheuttama trakeobronkiitti koiralla : kirjallisuuskatsaus ja kaksi tapausselostusta

Summary: Filaroides osleri causing tracheo-bronchitis in the dog : literature review and two case reports

Effect of feeding level during autumn and winter on breeding weight and result in single and pair-housed minks

Selostus: Syys- ja talviruokinnan vaikutus yksin ja pareittain kasvatettujen minkkien lisääntymistulokseen