Kitāb Fatḥ al-jawād bi-sharḥ Manẓūmat Ibn al-ʻImād / taṣnīf al-Shaykh al-Imām al-ʻĀlim al-ʻAllāmah shaykhinā wa-mawlānā Abū al-ʻAbbās al-Shihāb Aḥmad al-Ramlī al-Anṣārī al-Khazrajī : manuscript, 1542

بسم الله الرحمن الرحيم الحمد لله الذي بعث محمد صلى الله عليه وسلم رحمة للعالمين ... :Incipit

Sauerio orientale o vero Istorie de' cristiani illustri dell'Oriente li quali nelle parti orientali sono stati chiari per virtu, e pieta cristiana, dall'anno 1542 fino al 1600 : raccolte dalle lettere scritte in Europa da' religiosi della Compagnia di Giesù, e da altri autori /

Mode of access: Internet.

La Violencia intrafamiliar a partir de la ley 1542 de 2012. Análisis desde el derecho a la familia y la Declaración Universal de los Derechos Humanos

47 p.

Direct Visualization Of The Action Of Triton X-100 On Giant Vesicles Of Erythrocyte Membrane Lipids.

The raft hypothesis proposes that microdomains enriched in sphingolipids, cholesterol, and specific proteins are transiently formed to accomplish important cellular tasks. Equivocally, detergent-resistant membranes were initially assumed to be identical to membrane rafts, because of similarities between their compositions. In fact, the impact of detergents in membrane organization is still controversial. Here, we use phase contrast and fluorescence microscopy to observe giant unilamellar vesicles (GUVs) made of erythrocyte membrane lipids (erythro-GUVs) when exposed to the detergent Triton X-100 (TX-100). We clearly show that TX-100 has a restructuring action on biomembranes. Contact with TX-100 readily induces domain formation on the previously homogeneous membrane of erythro-GUVs at physiological and room temperatures. The shape and dynamics of the formed domains point to liquid-ordered/liquid-disordered (Lo/Ld) phase separation, typically found in raft-like ternary lipid mixtures. The Ld domains are then separated from the original vesicle and completely solubilized by TX-100. The insoluble vesicle left, in the Lo phase, represents around 2/3 of the original vesicle surface at room temperature and decreases to almost 1/2 at physiological temperature. This chain of events could be entirely reproduced with biomimetic GUVs of a simple ternary lipid mixture, 2:1:2 POPC/SM/chol (phosphatidylcholine/sphyngomyelin/cholesterol), showing that this behavior will arise because of fundamental physicochemical properties of simple lipid mixtures. This work provides direct visualization of TX-100-induced domain formation followed by selective (Ld phase) solubilization in a model system with a complex biological lipid composition.

Avaliação e intervenção socio-neuromotora de crianças com marasmo na primeira infancia

Universidade Estadual de Campinas . Faculdade de Educação Física

Enzymatic kinetic resolution of (RS)-1-(Phenyl)ethanols by Burkholderia cepacia lipase immobilized on magnetic nanoparticles

Lipase from Burkholderia cepacia immobilized on superparamagnetic nanoparticles using adsorption and chemisorption methodologies was efficiently applied as recyclable biocatalyst in the enzymatic kinetic resolution of (RS)-1-(phenyl)ethanols via transesterification reactions. (R)-Esters and the remaining (S)-alcohols were obtained with excellent enantiomeric excess (> 99%), which corresponds to a perfect process of enzymatic kinetic resolution (conversion 50%, E > 200). The transesterification reactions catalysed with B. cepacia lipase immobilized by the glutaraldehyde method showed the best results in terms of reusability, preserving the enzyme activity (conversion 50%, E > 200) for at least 8 successive cycles.