Performance of sustainable SCC mixes with mineral additions for use in precast concrete industry

The aim of this research was to study the impact that different mineral powders have on the properties of self-compacting concrete (SCC) in order to obtain relations that make it possible to optimize their dosages for being used in precast concrete applications. Different combinations and contents of cement, mineral additions (active and inert), superplasticizers, and aggregates are considered. A new approach for determining the saturation point of superplasticizers is introduced. The fresh state performance was assessed by means of the following tests: slump flow, V-funnel, and J-ring. Concrete compressive strength values at different ages up to 56 days have been retained as representative of the materials’ performance in its hardened state. All these properties have been correlated with SCC proportioning. As a result, a number of recommendations for the precast concrete industry arise to design more stable SCC mixes with a reduced carbon footprint.

Two-Year Monitoring of Water Samples from Dam of Iskar and the Black Sea, Bulgaria, by Molecular Analysis: Focus on Mycobacterium spp

The coast of the Bulgarian Black Sea is a popular summer holiday destination. The Dam of Iskar is the largest artificial dam in Bulgaria, with a capacity of 675 million m3. It is the main source of tap water for the capital Sofia and for irrigating the surrounding valley. There is a close relationship between the quality of aquatic ecosystems and human health as many infections are waterborne. Rapid molecular methods for the analysis of highly pathogenic bacteria have been developed for monitoring quality. Mycobacterial species can be isolated from waste, surface, recreational, ground and tap waters and human pathogenicity of nontuberculose mycobacteria (NTM) is well recognized. The objective of our study was to perform molecular analysis for key-pathogens, with a focus on mycobacteria, in water samples collected from the Black Sea and the Dam of Iskar. In a two year period, 38 water samples were collected-24 from the Dam of Iskar and 14 from the Black Sea coastal zone. Fifty liter water samples were concentrated by ultrafiltration. Molecular analysis for 15 pathogens, including all species of genus Mycobacterium was performed. Our results showed presence of Vibrio spp. in the Black Sea. Rotavirus A was also identified in four samples from the Dam of Iskar. Toxigenic Escherichia coli was present in both locations, based on markers for stx1 and stx2 genes. No detectable amounts of Cryptosporidium were detected in either location using immunomagnetic separation and fluorescence microscopy. Furthermore, mass spectrometry analyses did not detect key cyanobacterial toxins. On the basis of the results obtained we can conclude that for the period 2012-2014 no Mycobacterium species were present in the water samples. During the study period no cases of waterborne infections were reported.

Curso: En llegando a esta pasión II (Área escénica)

Coordina: José Luis Ibáñez, Auxiliar: Lic. Emilio Méndez Ríos

Vivendo e aprendendo: a literacia ao longo da vida

Dissertação de mest., Educação Social, Escola Superior de Educação e Comunicação, Univ. do Algarve, 2013

PPARβ/δ ameliorates fructose-induced insulin resistance in adipocytes by preventing Nrf2 activation

We studied whether PPARβ/δ deficiency modifies the effects of high fructose intake (30% fructose in drinking water) on glucose tolerance and adipose tissue dysfunction, focusing on the CD36-dependent pathway that enhances adipose tissue inflammation and impairs insulin signaling. Fructose intake for 8weeks significantly increased body and liver weight, and hepatic triglyceride accumulation in PPARβ/δ-deficient mice but not in wild-type mice. Feeding PPARβ/δ-deficient mice with fructose exacerbated glucose intolerance and led to macrophage infiltration, inflammation, enhanced mRNA and protein levels of CD36, and activation of the JNK pathway in white adipose tissue compared to those of water-fed PPARβ/δ-deficient mice. Cultured adipocytes exposed to fructose also exhibited increased CD36 protein levels and this increase was prevented by the PPARβ/δ activator GW501516. Interestingly, the levels of the nuclear factor E2-related factor 2 (Nrf2), a transcription factor reported to up-regulate Cd36 expression and to impair insulin signaling, were increased in fructose-exposed adipocytes whereas co-incubation with GW501516 abolished this increase. In agreement with Nrf2 playing a role in the fructose-induced CD36 protein level increases, the Nrf2 inhibitor trigonelline prevented the increase and the reduction in insulin-stimulated AKT phosphorylation caused by fructose in adipocytes. Protein levels of the well-known Nrf2 target gene NAD(P)H: quinone oxidoreductase 1 (Nqo1) were increased in water-fed PPARβ/δ-null mice, suggesting that PPARβ/δ deficiency increases Nrf2 activity; and this increase was exacerbated in fructose-fed PPARβ/δ-deficient mice. These findings indicate that the combination of high fructose intake and PPARβ/δ deficiency increases CD36 protein levels via Nrf2, a process that promotes chronic inflammation and insulin resistance in adipose tissue.

Authorship in scientific publications: analysis and recommendations.

In 2008, a Swiss Academies of Arts and Sciences working group chaired by Professor Emilio Bossi issued a "Memorandum on scientific integrity and the handling of misconduct in the scientific context", together with a paper setting out principles and procedures concerning integrity in scientific research. In the Memorandum, unjustified claims of authorship in scientific publications are referred to as a form of scientific misconduct - a view widely shared in other countries. In the Principles and Procedures, the main criteria for legitimate authorship are specified, as well as the associated responsibilities. It is in fact not uncommon for disputes about authorship to arise with regard to publications in fields where research is generally conducted by teams rather than individuals. Such disputes may concern not only the question who is or is not to be listed as an author but also, frequently, the precise sequence of names, if the list is to reflect the various authors' roles and contributions. Subjective assessments of the contributions made by the individual members of a research group may differ substantially. As scientific collaboration - often across national boundaries - is now increasingly common, ensuring appropriate recognition of all parties is a complex matter and, where disagreements arise, it may not be easy to reach a consensus. In addition, customs have changed over the past few decades; for example, the practice of granting "honorary" authorship to an eminent researcher - formerly not unusual - is no longer considered acceptable. It should be borne in mind that the publications list has become by far the most important indicator of a researcher's scientific performance; for this reason, appropriate authorship credit has become a decisive factor in the careers of young researchers, and it needs to be managed and protected accordingly. At the international and national level, certain practices have therefore developed concerning the listing of authors and the obligations of authorship. The Scientific Integrity Committee of the Swiss Academies of Arts and Sciences has collated the relevant principles and regulations and formulated recommendations for authorship in scientific publications. These should help to prevent authorship disputes and offer guidance in the event of conflicts.

Revue du XIXe siècle / L. Guérin, directeur-gérant

1854/12/15 (T2,VOL2).

Revue du XIXe siècle (Paris. 1854)

Variante(s) de titre : Revue du dix-neuvième siècle

Revue du XIXe siècle / L. Guérin, directeur-gérant

1854/04 (A1,T1)-1854/10 (A1,T1).

Revue du XIXe siècle / L. Guérin, directeur-gérant

1855/02/15 (T1,VOL1).

Recueil de pièces originales et de copies de pièces indiquées comme telles dans le dépouillement qui suit.

Contient : 1 « Instruction pour le reglement et entretenement des galleres du roy et armées de mer es partyes de Levant... Faict à Marseille, le vingtiesme jour d'aoust mil cinq cens soixante et dix » ; 2 « Description au vray de la construction du corps d'une gallere neufve, subtile ou bastardelle, qu'on pourra armer à galoche, c'est à dire quatrirame, et l'ordre qu'il convyent observer en ladicte construction » ; 3 « Estat abregé de la recepte et despense faicte pour le faict de l'advitaillement de l'armée de mer que le roy avoit deliberé mettre sus pour son service au pays et duché de Normendie... 1559 et 1560 » ; 4 « Advertissement à monseigneur de Biron, chevalier de l'ordre du roy, grand maistre et cappitaine general de son artillerye, de ce qui seroit bien necessaire pour le service dudict seigneur au faict de son artillerye au païs de Piedmont... Faict à Pignerolle, le quatreieme jour de janvier mil cinq cens soixante et douze ». Signé : « DE CARONDELET » ; 5 « Estat au vray du payement faict par Me François de La Gorse, conseiller du roy et tresorier de l'extraordinaire de ses guerres, de l'ordonnance et commandement de monseigneur le duc de Nivernois, pair de France, gouverneur et lieutenant general pour Sa Majesté au païs de Piemont et marquisat de Salusse, pour les estatz, pensions et entretenemens tant de luy que de plusieurs gentilz hommes, cappitaines, gouverneurs de places et autres entretenus pour le service de Sa Majesté au païs de Piemont et marquisat de Salusse, pour huict mois entiers, commencés le premier jour de janvier M.V.C. soixante treize et finis le dernier jour d'aoust ensuivant » ; 6 « Confessions de POLTROT sur les interrogatz à luy faicts de l'assasinat commis par luy en la personne de feu François de Lorraine, duc de Guise, au camp de St Hilaire pres St Mesmin... Du XXe jour de febvrier, l'an mil cinq cens soixante deux ». Copie ; 7 « Coppie de l'arrest donné au conseil privé du roy, le 29 janvier mil cinq cens soixante cinq, à la poursuitte de la maison de Guise, pour l'assassinat commis en la personne de feu monsieur le duc de Guise, François de Lorraine » ; 8 Mémoire sur la tactique militaire, à propos des guerres de religion en France. En italien ; 9 « Ligue faicte entre le roy Charle neufviesme et la royne d'Angletere » Elizabeth. En latin. Copie ; 10 « Instruction au sieur de Malras, ambassadeur pour le roy à Rome, sur le fait de l'abbaye de Vaucelles, scituée au pais de Cambresis... Signé : CHARLES,... Le dernier jour d'octobre mil cinq cens soixante et unze ». Copie ; 11 « Memoire touchant ladite abbaye de Vaucelles ». Copie ; 12 « Instruction à monseigneur d'Oisel, envoyé de la part du roy vers le roy d'Espagne. 1563. » Copie ; 13 « Extraict de l'instruction du sieur de Laubespine le jeune, envoyé par le roy en Espagne en 1564 » ; 14 « Memoire envoyé par le roy au sieur de Schomberg, estant de la part de Sa Majesté vers les princes de la Germanie, pour faire entendre ausdictz princes sur la mort de l'admiral... Fait à Paris, le 25e aoust 1572, signé : CHARLES » ; 15 Mémoire du duc DE NEVERS, contenant copie d'un état des deniers perçus par lui de 1549 à 1578 ; 16 « L'Ordre et reigle que anciennement se gardoit aux armées pour le faict et distribution des vivres de munition ». Copie ; 17 « Memoire » sur « des feux d'artifice de guerre » ; 18 « Discours sur les fortificacions... par LA TRUILLE, commissaire de l'artillerie du roy... 8 novembre 1566 » ; 19 « Reglement » fait par ceux de la religion réformée. 20 juillet 1567. Copie ; 20 « Ordonnances des cent Suisses de la garde du roy, en langaige d'allemant et françois... Signé : Guillaume Tonguiner,... Faict le seiziesme jour de janvier 1567 ». Copie ; 21 « Memoria di quello che EMILIO CAVRIANI,... ha visto... in cinque asedii dove s'e trovato in Italia ». En italien