983 resultados para Cabrera


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Os objetivos deste trabalho foram verificar a existência de interação entre genótipos de feijoeiro-comum e épocas de semeadura, avaliar a importância da interação complexa e verificar a necessidade de indicação de cultivares para cada época, em região de altitude intermediária nos estados do Paraná e Santa Catarina. Utilizaram-se avaliações de produtividade de grãos de 16 genótipos, em 12 ensaios realizados em duas épocas de semeadura. As análises de variância foram realizadas com decomposição da interação genótipos x ambientes. A percentagem complexa da interação para os pares de ambientes e também a correlação de Spearman entre épocas foram estimadas por meio de médias de produtividade e parâmetros de estabilidade dos genótipos, obtidos pela metodologia Annicchiarico. Detectaram-se diferenças entre épocas e presença de interação genótipos x épocas, mas com menor importância que as outras interações duplas com genótipos. As correlações de Spearman entre épocas mostraram interação predominantemente simples entre genótipos e épocas. A média da percentagem complexa da interação entre pares de ensaios mostrou que a alteração de classificação dos genótipos dentro de cada época tem a mesma magnitude do que a alteração entre épocas. Não é necessário indicar cultivares de feijoeiro comum para cada época isoladamente na região de estudo.

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Background: Differences in the distribution of genotypes between individuals of the same ethnicity are an important confounder factor commonly undervalued in typical association studies conducted in radiogenomics. Objective: To evaluate the genotypic distribution of SNPs in a wide set of Spanish prostate cancer patients for determine the homogeneity of the population and to disclose potential bias. Design, Setting, and Participants: A total of 601 prostate cancer patients from Andalusia, Basque Country, Canary and Catalonia were genotyped for 10 SNPs located in 6 different genes associated to DNA repair: XRCC1 (rs25487, rs25489, rs1799782), ERCC2 (rs13181), ERCC1 (rs11615), LIG4 (rs1805388, rs1805386), ATM (rs17503908, rs1800057) and P53 (rs1042522). The SNP genotyping was made in a Biotrove OpenArrayH NT Cycler. Outcome Measurements and Statistical Analysis: Comparisons of genotypic and allelic frequencies among populations, as well as haplotype analyses were determined using the web-based environment SNPator. Principal component analysis was made using the SnpMatrix and XSnpMatrix classes and methods implemented as an R package. Non-supervised hierarchical cluster of SNP was made using MultiExperiment Viewer. Results and Limitations: We observed that genotype distribution of 4 out 10 SNPs was statistically different among the studied populations, showing the greatest differences between Andalusia and Catalonia. These observations were confirmed in cluster analysis, principal component analysis and in the differential distribution of haplotypes among the populations. Because tumor characteristics have not been taken into account, it is possible that some polymorphisms may influence tumor characteristics in the same way that it may pose a risk factor for other disease characteristics. Conclusion: Differences in distribution of genotypes within different populations of the same ethnicity could be an important confounding factor responsible for the lack of validation of SNPs associated with radiation-induced toxicity, especially when extensive meta-analysis with subjects from different countries are carried out.

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Resumen Los turnos de trabajo tienen repercusión sobre el bienestar de los profesionales sanitarios influyendo en su calidad de vida. El objetivo principal de este estudio es describir las consecuencias que tiene el turno de trabajo diurno de 12 h respecto al de 7 h en los profesionales de enfermería que trabajan en Unidades de Cuidados Intensivos. Se trata así de un estudio descriptivo transversal en 2 hospitales de tercer nivel de Barcelona: Hospital Clínico y Hospital Vall d"Hebron (turnos de 7 h y 12 h respectivamente). La recogida de datos se ha realizado mediante cuestionario ad hoc de 29 preguntas cerradas, anónimo y autoadministrado, basado en 2 escalas: Standard Shiftwork Index y Shiftwork locus of control. Dichos datos fueron procesados a través del programa SPSS V.18.0. De las 85 encuestas realizadas 52 fueron válidas: 22 en el Hospital Clínico de Barcelona y 30 en el Hospital Vall d"Hebron. Cabe destacar que los profesionales encuestados que trabajan en turno de 12 h expresan niveles superiores de conciliación laboral y personal, concretamente en tiempo de ocio a disfrutar (× 2: 10,635; p = 0,031) y tiempo de dedicación familia-amigos, así como niveles más bajos de percepción de fatiga. No se han encontrado diferencias entre el tipo de turno y facilidad de desarrollo del trabajo profesional, a pesar de que el turno de 12 h presenta niveles más altos.

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Para conseguir una docencia de excelencia y calidad en la Universidad se requiere de una preparación por parte del profesorado que la debe impartir. Si esta formación comienza desde los primeros escalones de la Universidad, los profesores noveles, ésta les permitirá alcanzar unas competencias pedagógicas básicas que podrán ir ampliando y mejorando en el transcurso de su trayectoria docente.

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Peer-reviewed

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A particular property of the matched desiredimpulse response receiver is introduced in this paper, namely,the fact that full exploitation of the diversity is obtained withmultiple beamformers when the channel is spatially and timelydispersive. This particularity makes the receiver specially suitablefor mobile and underwater communications. The new structureprovides better performance than conventional and weightedVRAKE receivers, and a diversity gain with no needs of additionalradio frequency equipment. The baseband hardware neededfor this new receiver may be obtained through reconfigurabilityof the RAKE architectures available at the base station. Theproposed receiver is tested through simulations assuming UTRAfrequency-division-duplexing mode.

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A unified and general vision of different space-time processors is presented. Many popular receivers can beaccomodated, like V-RAKE receivers, weighted V-RAKE, or spatial narrowband beamforming. By makingappropriate assumptions on the space/time characteristic of the interference it is possible to enhance theperformance of the receiver through spatial/temporal pre-processors. These receivers will be tested in the FDDmode of UTRA.

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Forecasting coal resources and reserves is critical for coal mine development. Thickness maps are commonly used for assessing coal resources and reserves; however they are limited for capturing coal splitting effects in thick and heterogeneous coal zones. As an alternative, three-dimensional geostatistical methods are used to populate facies distributionwithin a densely drilled heterogeneous coal zone in the As Pontes Basin (NWSpain). Coal distribution in this zone is mainly characterized by coal-dominated areas in the central parts of the basin interfingering with terrigenous-dominated alluvial fan zones at the margins. The three-dimensional models obtained are applied to forecast coal resources and reserves. Predictions using subsets of the entire dataset are also generated to understand the performance of methods under limited data constraints. Three-dimensional facies interpolation methods tend to overestimate coal resources and reserves due to interpolation smoothing. Facies simulation methods yield similar resource predictions than conventional thickness map approximations. Reserves predicted by facies simulation methods are mainly influenced by: a) the specific coal proportion threshold used to determine if a block can be recovered or not, and b) the capability of the modelling strategy to reproduce areal trends in coal proportions and splitting between coal-dominated and terrigenousdominated areas of the basin. Reserves predictions differ between the simulation methods, even with dense conditioning datasets. Simulation methods can be ranked according to the correlation of their outputs with predictions from the directly interpolated coal proportion maps: a) with low-density datasets sequential indicator simulation with trends yields the best correlation, b) with high-density datasets sequential indicator simulation with post-processing yields the best correlation, because the areal trends are provided implicitly by the dense conditioning data.

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Es presenta un model de negoci de venda per Internet d’ aliments típics espanyols orientat principalment a les persones que han emigrat del nostre país. El motiu que dona lloc a aquest projecte no es altre que el constant increment de espanyols que decideixen buscar oportunitats fora del país, cosa que suposa una oportunitat de negoci. Per comprovar la sostenibilitat del projecte, es realitzarà un anàlisi de totes aquelles variables externes que pugin intervenir i afectar al desenvolupament de la activitat així com un estudi de mercat, un pla estratègic i un estudi financer que serveixi per assentar les bases d’un negoci que sens dubte està ple d’oportunitats.

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Aquest treball de final de carrera tracta sobre el futur del sistema de pensions a l’economia espanyola, i estudia l’estructura i evolució del sistema en el nostre país així com la legislació vigent i les mesures que el govern pretén instaurar. Aquesta investigació també profunditzarà en aquelles matèries i factors que pugin influir en la sostenibilitat de les pensions. Degut al envelliment de la població i la baixa taxa de natalitat a la Unió Europea, la majoria de països han pres mesures per assegurar la viabilitat dels seus sistemes. El treball analitzarà la direcció de les mesures preses per Espanya amb l’objectiu de saber com afectaran a l’economia del nostre país i al sistema de pensions

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The multicultural nature of our society requests new professional requirements at the Public Administration. There are news users that present specifics needs and conditions provoked by the legal situation and cultural origin. The research has two aims: 1) The assessment of Intercultural Competencies of the public employees of el Servicio de Empleo de Cataluña and 2) The design of a training program for the development of this competencies. The scope where are more needed this competencies are the capacity to solve intercultural problems, the intercultural communication, the knowledge of cultures and the migratory phenomena, and the role played by thestereotypes and the bias

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We tested for interactions between body mass index (BMI) and common genetic variants affecting serum urate levels, genome-wide, in up to 42569 participants. Both stratified genome-wide association (GWAS) analyses, in lean, overweight and obese individuals, and regression-type analyses in a non BMI-stratified overall sample were performed. The former did not uncover any novel locus with a major main effect, but supported modulation of effects for some known and potentially new urate loci. The latter highlighted a SNP at RBFOX3 reaching genome-wide significant level (effect size 0.014, 95% CI 0.008-0.02, Pinter= 2.6 x 10-8). Two top loci in interaction term analyses, RBFOX3 and ERO1LB-EDARADD, also displayed suggestive differences in main effect size between the lean and obese strata. All top ranking loci for urate effect differences between BMI categories were novel and most had small magnitude but opposite direction effects between strata. They include the locus RBMS1-TANK (men, Pdifflean-overweight= 4.7 x 10-8), a region that has been associated with several obesity related traits, and TSPYL5 (men, Pdifflean-overweight= 9.1 x 10-8), regulating adipocytes-produced estradiol. The top-ranking known urate loci was ABCG2, the strongest known gout risk locus, with an effect halved in obese compared to lean men (Pdifflean-obese= 2 x 10-4). Finally, pathway analysis suggested a role for N-glycan biosynthesis as a prominent urate-associated pathway in the lean stratum. These results illustrate a potentially powerful way to monitor changes occurring in obesogenic environment.

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Objetivando caracterizar a produção e a qualidade de bananas produzidas em diferentes condições de cultivo na ilha de Tenerife, foram estudadas três regiões da ilha (Cueva del Polvo, Hoya Melleque e Canaria Forestal), onde se produzem bananas ao ar livre das cultivares Gruesa, Gran Enana e Laja. Nas áreas de Cueva del Polvo e Hoya Melleque, emprega-se o cultivo convencional e, na propriedade Canaria Forestal, pratica-se o orgânico. Os espaçamentos adotados foram de 1,67 x 5,0 m, com duas plantas por cova; 1,3 x 3,0 m, com uma planta por cova, e 2,0 x 5,0 m, com duas plantas por cova, respectivamente, para as propriedades em Cueva del Polvo, Hoya Melleque e Canaria Forestal. Diante dos dados observados, é possível verificar que as plantas da cv. Gran Enana apresentam maior altura e as da cv. Gruesa, maior espessura de pseudocaule. Também se pode inferir que, dentre as áreas e cultivares estudadas, não houve grande variabilidade nas características físicas dos frutos. A produtividade média encontrada foi de 99,8 t.ha-1, valor considerado adequado.