321 resultados para 1374


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Mode of access: Internet.

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"Description of the coins relating to the age of Petrarch. By J. G. Pfister": v.2, p. [379]-398.

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"Francesco Petrarca ai posteri": p. [vii]-xvi.

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Tr. of: Africa.

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Mode of access: Internet.

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On the love of Petrarch.--On the poetry of Petrarch.--On the character of Petrarch.--A parallel between Dante and Petrarch.--Appendix: I. Specimens of Petrarch's Latin poetry. II. Specimens of Greek amatory poetry, from Sappho down to the writers of the lower empire. III. A theory of Platonic love, by Lorenzo de' Medici. IV. Comparative description of woman's beauty according to Platonic ideas, by the early Italian poets. V. Petrarch's unpublished letters in Italian (with facsimile) VI. A letter, in Latin, of Dante's lately discovered (Epistola "amico florentino") VII. Translations from Petrarch, by Barbarina lady Dacre.

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Mode of access: Internet.

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Printed in Plymouth, Eng.

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Prepared under the supervision of H.C. Maxwell Lyte. Text by R.F. Isaacson, vol. 1-15 (with G.J. Morris and H.E. Lawrence, vol. 1; C.B. Dawes, vol. 13-15); C.B. Dawes, vol. 16.

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übersetzt und mit Anmerkungen versehen von Prof. Dr. A. Sulzbach

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There appear to have been no previous literature-based or literature-oriented studies in telemedicine which have analysed raw citation data. Using a simple search strategy, the Web of Science was analysed up to the end of 2005 to give a snapshot of the field, and to identify matters which would need to be considered in larger scale bibliometric studies. Of the 3673 telemedicine documents retrieved, 2213 (60%) had been cited. Of 56,875 citation records, 32,460 unique citation formats were found. The most-cited paper, and the paper with the greatest annual citation rate, was Perednia and Allen's review article in JAMA, 1995. The two specialist telemedicine journals published 40% of all papers retrieved. In the general literature (i.e. excluding the two specialist journals) there were 1556 citations to their 1374 'citable' articles, apportioned in the ratio 76:24, almost exactly in accordance with the distribution of the articles themselves. However, each of the two specialist telemedicine journals cited itself in a proportion higher than its share of original articles, with an 'excess' of self-citations of 14% in the journal of Telemedicine and Telecare, and 19% in the Telemedicine journal and E-Health. Despite certain technical difficulties, there is considerable scope for bibliometric research in telemedicine.

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Bem-estar no trabalho, percepção de suporte do supervisor e estilos de liderança são temas que vêm despertando atenção crescente nos últimos tempos, de diversos pesquisadores no campo de estudos do comportamento organizacional. O objetivo desta pesquisa foi investigar o impacto da percepção do suporte do supervisor e dos estilos de liderança no bem-estar no trabalho. O construto bem-estar no trabalho no presente estudo foi representado por duas dimensões: satisfação no trabalho e comprometimento organizacional afetivo. A amostra foi composta por 200 trabalhadores que atuavam em empresas privadas e públicas, situadas no Estado de São Paulo, sendo 110 mulheres e 90 homens, distribuídos entre solteiros e casados. O instrumento de coleta de dados foi um questionário composto por quatro escalas que mediram as variáveis: percepção de suporte do supervisor, estilos de lideranças, satisfação no trabalho e comprometimento organizacional afetivo. Para a análise dos dados utilizou-se um programa estatístico. Foram calculadas estatísticas descritivas das variáveis do estudo (médias, desvios-padrão e correlações bivariadas) e modelos de regressão multivariada para se investigar os impactos causados por percepção do suporte do supervisor e por estilos de liderança sobre bem-estar no trabalho, representado por vínculos com o trabalho (satisfação no trabalho) e com a organização (comprometimento organizacional afetivo). Os resultados deste estudo, revelaram maiores impactos do suporte do supervisor do que de estilos de liderança sobre bem-estar no trabalho. Ao final, algumas considerações e recomendações serão feitas destacando-se a importância do bem-estar no trabalho sobre a saúde dos trabalhadores e das organizações.

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A range of particulate delivery systems have been considered as vaccine adjuvants. Of these systems, liposomes offer a range of advantages including versatility and flexibility in design format and their ability to incorporate a range of immunomodulators and antigens. Here we briefly outline research, from within our laboratories, which focused on the systematic evaluation of cationic liposomes as vaccines adjuvants. Our aim was to identify physicochemical characteristics that correlate with vaccine efficacy, with particular consideration of the interlink between depot-forming action and immune responses. A variety of parameters were investigated and over a range of studies we have confirmed that cationic liposomes, based on dimethyldioctadecylammonium bromide and trehalose 6,6'-dibehenate formed a depot at the injection site, which stimulates recruitment of antigen presenting cells to the injection site and promotes strong humoral and cell-mediated immune responses. Physicochemical factors which promote a strong vaccine depot include the combination of a high cationic charge and electrostatic binding of the antigen to the liposome system and the use of lipids with high transition temperatures, which form rigid bilayer vesicles. Reduction in vesicle size of cationic vesicles did not promote enhanced drainage from the injection site. However, reducing the cationic nature through substitution of the cationic lipid for a neutral lipid, or by masking of the charge using PEGylation, resulted in a reduced depot formation and reduced Th1-type immune responses, while Th2-type responses were less influenced. These studies confirm that the physicochemical characteristics of particulate-based adjuvants play a key role in the modulation of immune responses.