Improving the railway’s understanding of accident causation through an integrated approach to human factors analysis and technical safety data recording

This paper describes a safety data recording and analysis system that has been developed to capture safety occurrences including precursors using high-definition forward-facing video from train cabs and data from other train-borne systems. The paper describes the data processing model and how events detected through data analysis are related to an underlying socio-technical model of accident causation. The integrated approach to safety data recording and analysis insures systemic factors that condition, influence or potentially contribute to an occurrence are captured both for safety occurrences and precursor events, providing a rich tapestry of antecedent causal factors that can significantly improve learning around accident causation. This can ultimately provide benefit to railways through the development of targeted and more effective countermeasures, better risk models and more effective use and prioritization of safety funds. Level crossing occurrences are a key focus in this paper with data analysis scenarios describing causal factors around near-miss occurrences. The paper concludes with a discussion on how the system can also be applied to other types of railway safety occurrences.

A simple and unified approach to human voluntary movements

In his provocative article, F. Mechsner (2004) advances the thesis that human voluntary movements are subject to "psychological" or "perceptual -cognitive" control and are thus organized "without regard to efferent patterns" (p. 355). Rather than considering in detail the experiments that he proffered by way of support, the present author discusses the degree to which that supposition has appeal on the grounds of simplicity and is defined in terms that are compatible with a unified science.

A Synergistic Approach to Human Rights and Public Health Ethics: Effective or a Source of Conflict?

Commentaire / Commentary

A Systems-Level Approach to Human Epileptic Seizures

Epileptic seizures are due to the pathological collective activity of large cellular assemblies. A better understanding of this collective activity is integral to the development of novel diagnostic and therapeutic procedures. In contrast to reductionist analyses, which focus solely on small-scale characteristics of ictogenesis, here we follow a systems-level approach, which combines both small-scale and larger-scale analyses. Peri-ictal dynamics of epileptic networks are assessed by studying correlation within and between different spatial scales of intracranial electroencephalographic recordings (iEEG) of a heterogeneous group of patients suffering from pharmaco-resistant epilepsy. Epileptiform activity as recorded by a single iEEG electrode is determined objectively by the signal derivative and then subjected to a multivariate analysis of correlation between all iEEG channels. We find that during seizure, synchrony increases on the smallest and largest spatial scales probed by iEEG. In addition, a dynamic reorganization of spatial correlation is observed on intermediate scales, which persists after seizure termination. It is proposed that this reorganization may indicate a balancing mechanism that decreases high local correlation. Our findings are consistent with the hypothesis that during epileptic seizures hypercorrelated and therefore functionally segregated brain areas are re-integrated into more collective brain dynamics. In addition, except for a special sub-group, a highly significant association is found between the location of ictal iEEG activity and the location of areas of relative decrease of localised EEG correlation. The latter could serve as a clinically important quantitative marker of the seizure onset zone (SOZ).

An approach to visual cortex operation: optical neuron model

Several works have been published in the last years concerning the modelling and implementation of the visual cortex operation. Most of them present simple neurons with just two different responses, namely inhibitory and excitatory. Some of the different types of visual cortex cells are simulated in these configurations.

Gene-based approach to human gene-phenotype correlations

Elucidating the genetic basis of human phenotypes is a major goal of contemporary geneticists. Logically, two fundamental and contrasting approaches are available, one that begins with a phenotype and concludes with the identification of a responsible gene or genes; the other that begins with a gene and works toward identifying one or more phenotypes resulting from allelic variation of it. This paper provides a conceptual overview of phenotype-based vs. gene-based procedures with emphasis on gene-based methods. A key feature of a gene-based approach is that laboratory effort first is devoted to developing an assay for mutations in the gene under regard; the assay then is applied to the evaluation of large numbers of unrelated individuals with a variety of phenotypes that are deemed potentially resulting from alleles at the gene. No effort is directed toward chromosomally mapping the loci responsible for the phenotypes scanned. Example is made of my laboratory’s successful use of a gene-based approach to identify genes causing hereditary diseases of the retina such as retinitis pigmentosa. Reductions in the cost and improvements in the speed of scanning individuals for DNA sequence anomalies may make a gene-based approach an efficient alternative to phenotype-based approaches to correlating genes with phenotypes.

The Illinois Commission on Human Relations presents a human approach to human problems : the third annual Statewide Human Relations Conference : program report and evaluation submitted to the Illinois Humanities Council and conference participants.

Cover title.

A simple and unified approach to human voluntary movements

In his provocative article, F. Mechsner (2004) advances the thesis that human voluntary movements are subject to psychological or perceptual -cognitive control and are thus organized without regard to efferent patterns (p. 355). Rather than considering in detail the experiments that he proffered by way of support, the present author discusses the degree to which that supposition has appeal on the grounds of simplicity and is defined in terms that are compatible with a unified science.

Missionary survey as an aid to intelligent co-operation in foreign missions, by Roland Allen, and Thomas Cochrane.

http://www.archive.org/details/missionarysurvey13360gut

Actividades realizadas por la Comisión Económica para América Latina y el Caribe (CEPAL) para el fomento de la cooperación entre países y regiones en desarrollo (agosto de 1983 a julio de 1984) = Activities carried out by the Economic Commission for Latin America and the Caribbean (ECLAC) to promote co-operation among developing countries and regions (August 1983 to July 1984)

Resena las actividades de promocion de la cooperacion tecnica y economica entre paises en desarrollo realizadas por CEPAL en los planos regional e interregional, destacando los aportes hechos a las reuniones tecnicas convocadas por el Comite de Seguimiento y Coordinacion en el bienio 1983-1984.

Guía para la cooperación técnica entre países en desarrollo (CTPD): oferta y directorio de instituciones = Guide to technical co-operation among developing countries (TCDC): TCDC supply and directory of institutions

Proporciona orientacion a demandantes potenciales de CTPD y presenta una vision completa sobre las actividades de oferta en la region. Incluye 1) informacion por paises: politicas, procedimientos, capacidad nacional y experiencias, 2) informacion por areas de especializacion: agricultura y pesca, administracion y desarrollo, educacion, industria, recursos naturales, transporte y comunicaciones, salud, y 3) directorio de instituciones especializadas en CTPD.

Guía revisada para la cooperación técnica entre países en desarrollo (CTPD): oferta y directorio de instituciones = Revised guide to technical co-operation among developing countries (TCDC): supply and directory of institutions

Publicación bilingüe

Lineamientos de un programa regional para el fortalecimiento de la cooperación entre redes y sistemas nacionales de información para el desarrollo en América Latina y el Caribe (INFOLAC) = Basic principles for a regional programme to strengthen co-operation among national information networks and systems for development in Latin America and the Caribbean (INFOLAC)

Contiene antecedentes y lineamientos para formular e impulsar un programa regional de cooperacion entre redes y sistemas nacionales de informacion existentes en America Latina y el Caribe.