From evolution to co-evolution – An empirical study of the role of innovation, policy and public research in industrial dynamics

In the past decades since Schumpeter’s influential writings economists have pursued research to examine the role of innovation in certain industries on firm as well as on industry level. Researchers describe innovations as the main trigger of industry dynamics, while policy makers argue that research and education are directly linked to economic growth and welfare. Thus, research and education are an important objective of public policy. Firms and public research are regarded as the main actors which are relevant for the creation of new knowledge. This knowledge is finally brought to the market through innovations. What is more, policy makers support innovations. Both actors, i.e. policy makers and researchers, agree that innovation plays a central role but researchers still neglect the role that public policy plays in the field of industrial dynamics. Therefore, the main objective of this work is to learn more about the interdependencies of innovation, policy and public research in industrial dynamics. The overarching research question of this dissertation asks whether it is possible to analyze patterns of industry evolution – from evolution to co-evolution – based on empirical studies of the role of innovation, policy and public research in industrial dynamics. This work starts with a hypothesis-based investigation of traditional approaches of industrial dynamics. Namely, the testing of a basic assumption of the core models of industrial dynamics and the analysis of the evolutionary patterns – though with an industry which is driven by public policy as example. Subsequently it moves to a more explorative approach, investigating co-evolutionary processes. The underlying questions of the research include the following: Do large firms have an advantage because of their size which is attributable to cost spreading? Do firms that plan to grow have more innovations? What role does public policy play for the evolutionary patterns of an industry? Are the same evolutionary patterns observable as those described in the ILC theories? And is it possible to observe regional co-evolutionary processes of science, innovation and industry evolution? Based on two different empirical contexts – namely the laser and the photovoltaic industry – this dissertation tries to answer these questions and combines an evolutionary approach with a co-evolutionary approach. The first chapter starts with an introduction of the topic and the fields this dissertation is based on. The second chapter provides a new test of the Cohen and Klepper (1996) model of cost spreading, which explains the relationship between innovation, firm size and R&D, at the example of the photovoltaic industry in Germany. First, it is analyzed whether the cost spreading mechanism serves as an explanation for size advantages in this industry. This is related to the assumption that the incentives to invest in R&D increase with the ex-ante output. Furthermore, it is investigated whether firms that plan to grow will have more innovative activities. The results indicate that cost spreading serves as an explanation for size advantages in this industry and, furthermore, growth plans lead to higher amount of innovative activities. What is more, the role public policy plays for industry evolution is not finally analyzed in the field of industrial dynamics. In the case of Germany, the introduction of demand inducing policy instruments stimulated market and industry growth. While this policy immediately accelerated market volume, the effect on industry evolution is more ambiguous. Thus, chapter three analyzes this relationship by considering a model of industry evolution, where demand-inducing policies will be discussed as a possible trigger of development. The findings suggest that these instruments can take the same effect as a technical advance to foster the growth of an industry and its shakeout. The fourth chapter explores the regional co-evolution of firm population size, private-sector patenting and public research in the empirical context of German laser research and manufacturing over more than 40 years from the emergence of the industry to the mid-2000s. The qualitative as well as quantitative evidence is suggestive of a co-evolutionary process of mutual interdependence rather than a unidirectional effect of public research on private-sector activities. Chapter five concludes with a summary, the contribution of this work as well as the implications and an outlook of further possible research.

Evaluation of coupled ocean-atmosphere simulations of northern hemisphere extratropical climates in the mid-Holocene

We have used the BIOME4 biogeography–biochemistry model and comparison with palaeovegetation data to evaluate the response of six ocean–atmosphere general circulation models to mid-Holocene changes in orbital forcing in the mid- to high-latitudes of the northern hemisphere. All the models produce: (a) a northward shift of the northern limit of boreal forest, in response to simulated summer warming in high-latitudes. The northward shift is markedly asymmetric, with larger shifts in Eurasia than in North America; (b) an expansion of xerophytic vegetation in mid-continental North America and Eurasia, in response to increased temperatures during the growing season; (c) a northward expansion of temperate forests in eastern North America, in response to simulated winter warming. The northward shift of the northern limit of boreal forest and the northward expansion of temperate forests in North America are supported by palaeovegetation data. The expansion of xerophytic vegetation in mid-continental North America is consistent with palaeodata, although the extent may be over-estimated. The simulated expansion of xerophytic vegetation in Eurasia is not supported by the data. Analysis of an asynchronous coupling of one model to an equilibrium-vegetation model suggests vegetation feedback exacerbates this mid-continental drying and produces conditions more unlike the observations. Not all features of the simulations are robust: some models produce winter warming over Europe while others produce winter cooling. As a result, some models show a northward shift of temperate forests (consistent with, though less marked than, the expansion shown by data) and others produce a reduction in temperate forests. Elucidation of the cause of such differences is a focus of the current phase of the Palaeoclimate Modelling Intercomparison Project.

Synergistic feedbacks between ocean and vegetation on mid- and high-latitude climates during the mid-Holocene

Simulations with the IPSL atmosphere–ocean model asynchronously coupled with the BIOME1 vegetation model show the impact of ocean and vegetation feedbacks, and their synergy, on mid- and high-latitude (>40°N) climate in response to orbitally-induced changes in mid-Holocene insolation. The atmospheric response to orbital forcing produces a +1.2 °C warming over the continents in summer and a cooling during the rest of the year. Ocean feedback reinforces the cooling in spring but counteracts the autumn and winter cooling. Vegetation feedback produces warming in all seasons, with largest changes (+1 °C) in spring. Synergy between ocean and vegetation feedbacks leads to further warming, which can be as large as the independent impact of these feedbacks. The combination of these effects causes the high northern latitudes to be warmer throughout the year in the ocean–atmosphere-vegetation simulation. Simulated vegetation changes resulting from this year-round warming are consistent with observed mid-Holocene vegetation patterns. Feedbacks also impact on precipitation. The atmospheric response to orbital-forcing reduces precipitation throughout the year; the most marked changes occur in the mid-latitudes in summer. Ocean feedback reduces aridity during autumn, winter and spring, but does not affect summer precipitation. Vegetation feedback increases spring precipitation but amplifies summer drying. Synergy between the feedbacks increases precipitation in autumn, winter and spring, and reduces precipitation in summer. The combined changes amplify the seasonal contrast in precipitation in the ocean–atmosphere-vegetation simulation. Enhanced summer drought produces an unrealistically large expansion of temperate grasslands, particularly in mid-latitude Eurasia.

Welche Typen von Autokratien sind leistungsfähiger und warum? : eine empirische Analyse auf Grundlage der Selektoratstheorie = Which type of autocracy performs better, and why?

Performanzunterschiede zwischen verschiedenen Autokratietypen wie Monarchien, Militär-, Ein-Parteien- und begrenzten Mehr-Parteien-Regimen sind bis auf wenige Ausnahmen bisher relativ unerforscht. Deshalb widmet sich diese Arbeit folgenden Forschungsfragen: Gibt es Performanzunterschiede zwischen verschiedenen Autokratietypen? Wenn ja, wie gestalten sich diese und wie lassen sie sich erklären? Auf Grundlage der Selektoratstheorie von Bueno de Mesquite et al. wird die Hypothese aufgestellt, dass die Performanz politischer Regime mit der Größe der Winning Coalition steigt. Da verschiedene Autokratietypen unterschiedlich große Winning Coalitions haben, wird angenommen, dass es deutliche Performanzunterschiede zwischen diesen Typen gibt. Als Performanzkriterien dienen in dieser Arbeit wirtschaftlicher Wohlstand, soziale Sicherheit und ökologische Nachhaltigkeit. Aus diesen drei Kriterien wird zusätzlich ein Indikator allgemeiner Performanz gebildet. Die empirische Untersuchung erfolgt mit den Daten des Quality-of-Governement-Datensatzes und erstreckt sich über 140 autokratische Länder im Zeitraum von 1972 bis 2010. Die Daten werden mittels Time-Series-Cross-Section-Regressionen analysiert. Die Ergebnisse der Analysen entsprechen nur teilweise den Erwartungen. Die Größe der Winning Coalition wirkt positiv auf die wirtschaftliche Wohlfahrt und die soziale Sicherheit und damit auch auf die allgemeine Performanz aus. Entgegen den Erwartungen sinkt die ökologische Performanz jedoch mit steigender Größe der Winning Coalition. Auch die Befunde bezüglich der Performanz verschiedener Autokratietypen entsprechen nicht den Erwartungen. So sind Ein-Parteien-Regime insgesamt leistungsfähiger als Mehr-Parteien-Regime, Militär-Regime und Monarchien. Militär-Regime sind leistungsfähiger als Monarchien und tendenziell auch als Mehr-Parteien-Regime.

N-(3-Cyanophenyl)-2-phenylacetamide, an effective inhibitor of morbillivirus-induced membrane fusion with low cytotoxicity

Based on the structural similarity of viral fusion proteins within the family Paramyxoviridae, we tested recently described and newly synthesized acetanilide derivatives for their capacity to inhibit measles virus (MV)-, canine distemper virus (CDV)- and Nipah virus (NiV)-induced membrane fusion. We found that N-(3-cyanophenyl)-2-phenylacetamide (compound 1) has a high capacity to inhibit MV- and CDV-induced (IC(50) muM), but not NiV-induced, membrane fusion. This compound is of outstanding interest because it can be easily synthesized and its cytotoxicity is low [50 % cytotoxic concentration (CC(50)) >/= 300 muM], leading to a CC(50)/IC(50) ratio of approximately 100. In addition, primary human peripheral blood lymphocytes and primary dog brain cell cultures (DBC) also tolerate high concentrations of compound 1. Infection of human PBMC with recombinant wild-type MV is inhibited by an IC(50) of approximately 20 muM. The cell-to-cell spread of recombinant wild-type CDV in persistently infected DBC can be nearly completely inhibited by compound 1 at 50 muM, indicating that the virus spread between brain cells is dependent on the activity of the viral fusion protein. Our findings demonstrate that this compound is a most applicable inhibitor of morbillivirus-induced membrane fusion in tissue culture experiments including highly sensitive primary cells.

Reibschlüssige Greifsysteme für die automatische Handhabung im Materialfluss

Die personalintensive manuelle Durchführung notwendiger Handhabungsaufgaben im Materialfluss ist bedingt durch die oftmals vielfältig auftretenden charakteristischen Eigenschaften der zu behandelnden Stückgutobjekte. Typische Beispiele hierfür sind die Tätigkeiten des Kommissionierens und Sortierens, geprägt durch einen hohen Anteil manueller Tätigkeiten zur Handhabung wie: Vereinzeln, Greifen, Bewegen, Auf- und Abstapeln, Ordnen, Beladen und Ähnliche. Innovative Greifersysteme zur Stückguthandhabung eröffnen neue Möglichkeiten zur weiteren Automatisierung auch in diesem Bereich. Ein Lösungsansatz zur Entwicklung neuer Greifsysteme ist es, gezielt Friktionskräfte in Oberflächenbereiche des zu greifenden Objektes einzubringen und diese für den Handhabungsvorgang z.B. als Haltekräfte zu nutzen. Bei guten Reibwerten und entsprechender Anordnung der Wirkelemente können Objekte auch dann rein reibschlüssig gegriffen werden, wenn deren Oberfläche nur seitlich und von oben zugänglich ist, wie etwa Kartons im Packmusterverbund auf der Palette.

Der Übergang ins Hochschulstudium: Prozesse und Mechanismen am Beispiel der deutschen Schweiz

Im Allgemeinen wird zum einen die Auffassung geteilt, dass auch ein Land wie die Schweiz auf ein steigendes Angebot qualifizierter und hochqualifizierter Arbeitskräfte angewiesen ist, um wirtschaftliche Prosperität und allgemeine Wohlfahrt dauerhaft sicherstellen zu können (vgl. SKBF 2010). Zum anderen wird dem modernen Bildungssystem – unter Gewährleistung zumindest formaler Chancengleichheit – die Aufgabe zugeschrieben, mittels ausreichender Bildungsgelegenheiten für dieses Angebot an Humankapital zu sorgen (vgl. Müller und Kogan 2010; Müller et al. 1997; Seibert et al. 2010).

Von jüdischer Wohlfahrtspflege

hrsg. von der Zentralwohlfahrtsstelle der deutschen Juden. [Hrsg.[[Elektronische Ressource]] : Eugen Caspary]

Der Landesverein zur Erziehung israelitischer Waisen im Grossherzogtum Baden in seinen ersten fünfundzwanzig Jahren : 1888 - 1913

Im Auftr. des Vereinsvorstands dargest. von S. Grzymisch

Wohlfahrtseinrichtungen für Israeliten in Frankfurt a. M. : gewidmet der am 7. u. 8. Juli 1902 in Frankfurt a. M. ... Generalversammlung des Rabbiner-Verbandes in Deutschland

von A. Freimann

Die Wohlthätigkeit bei den Juden im alten Frankfurt

von M. Horovitz

Die Armenpflege für Ortsangesessene in der Frankfurter israelitischen Gemeinde : nach e. Referat, erstattet bei der Kriegstagung des "Jüdischen Frauenbundes" am 16. Januar 1916

von Arnold Lazarus

Zur Verbesserung der Lage unserer öst.-ung. Glaubensgenossen in Jerusalem

von Simon Löffler