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Familial structural rearrangements of chromosomes represent a factor of malformation risk that could vary over a large range, making genetic counseling difficult. However, they also represent a powerful tool for increasing knowledge of the genome, particularly by studying breakpoints and viable imbalances of the genome. We have developed a collaborative database that now includes data on more than 4100 families, from which we have developed a web site called HC Forum® (http://HCForum.imag.fr). It offers geneticists assistance in diagnosis and in genetic counseling by assessing the malformation risk with statistical models. For researchers, interactive interfaces exhibit the distribution of chromosomal breakpoints and of the genome regions observed at birth in trisomy or in monosomy. Dedicated tools including an interactive pedigree allow electronic submission of data, which will be anonymously shown in a forum for discussions. After validation, data are definitively registered in the database with the email of the sender, allowing direct location of biological material. Thus HC Forum® constitutes a link between diagnosis laboratories and genome research centers, and after 1 year, more than 700 users from about 40 different countries already exist.

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This paper reports on an ongoing partnership between Queensland University of Technology and Volunteering Queensland regarding the development and revision of a website for community leaders. The website, designed in late 2003, was established to provide a range of learning activities for community leaders including a problem based learning activity, case studies of community leaders and a range of resources deemed significant for leaders in the community. To date, anecdotal evidence as well as some more hard evidence (i.e. number of visits to the site), indicates that the site appears to be a valuable resource for community leaders. The purpose of this paper was firstly to investigate the utility of the site and secondly to consider some bigger issues concerning its sustainability. To achieve this, the paper explores the perceptions of (i) a group of community leaders regarding the strengths and weaknesses of the site; and (ii) key stakeholders (from QUT and Volunteering Queensland) who participated in a focus group discussion to consider important issues relating to its management and sustainability. Themes emerging from the two groups are provided and implications for small scale partnership projects such as this one are discussed.

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Structure of University lecturer’s web-site is suggested. A need for higher education system hyperspace is demonstrated.

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The information architecture supports information retrieval by users in Web environment. The design should be center in the information user, favoring usability. The Faculty of Industrial Engineering and Tourism of the Universidad Central "Marta Abreu" de Las Villas, lacks a site that enhances the disclosure of information to its members. Are presented as objectives of the study: 1) conduct a user survey to identify information needs of users, 2) establish guidelines for information architecture for the institution focused on users, 3) designing the information architecture for the institution and 4) designed to evaluate the proposal. Are presented as objectives of the study: 1) to realize a user study to identify the information needs of users, 2) establish guidelines for information architecture for the institution focused on users, 3) to design the information architecture for the institution and 4) to evaluate the proposal designed. To obtain results are used methods in the theoretical and empirical levels. Besides, are use techniques that favored the design and evaluation. Is designed the intranet of the Faculty of Industrial Engineering and Tourism. Is evaluated the proposed design for the validation of the results.

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This paper presents a web based expert system application that carries out an initial assessment of the feasibility of a web project. The system allows detection of inconsistency problems before design starts, and suggests correcting actions to solve them. The developed system presents important advantages not only for determining the feasibility of a web project but also by acting as a means of communication between the client company and the web development team, making the requirements specification clearer.

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To support student learning in a large Metabolism and Nutrition class, we have introduced a web-based package, using a commercially available program, WebCT. The package was developed at a minimal cost and with limited resources. In addition to downloadable (PDF) versions of lecture Powerpoint presentations, tutorial outlines and a practical class exercise, web-based self-directed learning exercises were included to reinforce and extend lecture material in an active learning environment. The web-site also contained a variety of formative and summative assessment tasks that examined both factual recall and higher order thinking Detailed course information, timetables and a bulletin board were also readily accessible. Student usage of the site was generally high, but varied widely between individual students. Students who achieved a high overall score for the course completed on average three times as many formative assessment items and achieved a higher score for all tests than students who did poorly. Student feedback about the site was very positive with the majority of students reporting that the course material and assessment items that were available were useful to their learning. Administration of the course was also facilitated. (C) 2001 IUBMB. Published by Elsevier Science Ltd. All rights reserved.

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A manutenção do conteúdo web pode ser uma tarefa difícil, especialmente se considerarmos websites em que muitos utilizadores têm permissões para alterar o seu conteúdo. Um exemplo deste tipo de websites são os wikis. Se por um lado permitem rápida disseminação de conhecimento, por outro lado implicam um grande esforço para verificar a qualidade do seu conteúdo. Nesta tese analisamos diferentes abordagens à modelação de websites, especialmente para a verificação de conteúdo, onde contribuímos com uma extensão à ferramenta VeriFLog para a tornar mais adequada à verificação de conteúdos em websites colaborativos.

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Aquesta memòria tracta sobre el desenvolupament d’una aplicació en un portal web, la qual ha de ser un suport per a que els entrenadors puguin controlar i analitzar els entrenaments de cada un dels seus esportistes, sense la necessitat de tenir que perdre molt de temps en la captació, transmissió i processament de la informació resultant de realitzar un entrenament. Aquesta aplicació neix amb la intenció de ser una eina útil tant per entrenadors, metges i esportistes, en l’obtenció dels objectius fixats.

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Este documento explica la metodología de trabajo utilizada durante el desarrollo de este proyecto. El resultado obtenido ha sido un producto que forma parte del portal web Luxury Porperties. Luxury Properties es una marca comercial, creada por la compañía Luxury Dreams, para identificar un portal web especializado en las propiedades de lujo. Para desarrollar este concepto, la empresa compró el dominio luxuryproperties.es con el objetivo de crear un sistema que implemente toda la lógica de negocio necesaria para la publicidad y mercadeo de sus productos. Al final del documento se encuentran las recomendaciones y las futuras valoraciones a tener en cuenta por el cliente en futuras ampliaciones del portal.

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PADICAT is the web archive created in 2005 in Catalonia (Spain ) by the Library of Catalonia (BC ) , the National Library of Catalonia , with the aim of collecting , processing and providing permanent access to the digital heritage of Catalonia . Its harvesting strategy is based on the hybrid model ( of massive harvesting . SPA top level domain ; selective compilation of the web site output of Catalan organizations; focused harvesting of public events) . The system provides open access to the whole collection , on the Internet . We consider necessary to complement the current search for new and visualization software with open source software tool, CAT ( Curator Archiving Tool) , composed by three modules aimed to effectively managing the processes of human cataloguing ; to publish directories where the digital resources and special collections ; and to offer statistical information of added value to end users. Within the framework of the International Internet Preservation Consortium meeting ( Vienna 2010) , the progress in the development of this new tool, and the philosophy that has motivated his design, are presented to the international community.

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Most life science processes involve, at the atomic scale, recognition between two molecules. The prediction of such interactions at the molecular level, by so-called docking software, is a non-trivial task. Docking programs have a wide range of applications ranging from protein engineering to drug design. This article presents SwissDock, a web server dedicated to the docking of small molecules on target proteins. It is based on the EADock DSS engine, combined with setup scripts for curating common problems and for preparing both the target protein and the ligand input files. An efficient Ajax/HTML interface was designed and implemented so that scientists can easily submit dockings and retrieve the predicted complexes. For automated docking tasks, a programmatic SOAP interface has been set up and template programs can be downloaded in Perl, Python and PHP. The web site also provides an access to a database of manually curated complexes, based on the Ligand Protein Database. A wiki and a forum are available to the community to promote interactions between users. The SwissDock web site is available online at http://www.swissdock.ch. We believe it constitutes a step toward generalizing the use of docking tools beyond the traditional molecular modeling community.

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Aquest treball té com a finalitat, d'una banda, col·laborar a determinar les mancances, tant de disseny com de contingut, que té actualment el web dels Estudis d'Humanitats i Filologia de la UOC i, de l'altra, fer una proposta d'un nou disseny, que inclogui la reestructuració dels continguts.

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Des de fa ja alguns anys que el sector de la construcció està malmès degut a la crisi econòmica actual i moltes de les empreses que hi ha no aconsegueixen sortir del pou i tenen seriosos problemes per a vendre els seus productes o serveis. És aquí on sorgeix una magnífica possibilitat d'utilitzar tècniques d'usabilitat i accessibilitat Web que poden permetre a les empreses del sector de la construcció millorar els ratis tant de captació com de fidelització de clients ja que la idea és aconseguir realitzar una Web pensada en l'usuari i per l'usuari tenint en compte sempre les seves necessitats. Com el sector és molt estès i per ser competitiu cal tenir algun factor diferenciador, com per exemple el de la sostenibilitat que està tan de moda, en aquest projecte s'ha volgut treballar amb una empresa que acompleix tots dos requisits: ven parquet de bambú i alhora aquesta planta és totalment sostenible.

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Desenvolupament d'una aplicació web per a la recollida i classificació d'informació en entorns virtuals d'interacció síncrona: xat + classificació automàtica de les converses generades + les seves pròpies interaccions en funció d'unes categories existents + fitxers log.