854 resultados para Utero Cáncer.
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Tesis (MaestrÃa en Ciencias con Especialidad en BiologÃa Molecular e IngenierÃa Genética) UANL
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Tesis (MaestrÃa en Ciencias con Especialidad en MicrobiologÃa) UANL
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Tesis (MaestrÃa en Ciencias con Especialidad en BiologÃa Molecular e IngenierÃa Genética) UANL
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Tesis (MaestrÃa en Ciencias con Orientación en BiologÃa Molecular e IngenierÃa Genética) U.A.N.L., 2006.
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Tesis (Especialidad en GinecologÃa y Obstetricia). U. A. N. L.
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Tesis (Doctorado en Ciencias con Especialidad en BiologÃa Moleculare IngenierÃa Genética) UANL
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Tesis ( Doctor en Ciencias con Especialidad en BiotecnologÃa) U.A.N.L.
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Pós-graduação em Biologia Geral e Aplicada - IBB
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Pós-graduação em Patologia - FMB
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Estudio descriptivo en el que se incluyeron 3953 papanicolaou, con la nomenclatura del Sistema Bethesda. Justificación: proque se cree necesario conocer la realidad del medio sobre patologÃa cervical. Resultados: dentro de lÃmites normales 7, cambios celulares benignos 76.5, células escamosas atÃpicas de significancia indeterminada ASCUS 12.2neoplasia intraepitelial de bajo grado LIE BG 1.7, neoplasia intraepitelial de alto grado LIEAG 0, 7, carcinoma de células escamosas 0,6, células glandulares atÃpicas de significancia indeterminada AGUS
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Early preterm birth (<32 weeks) is associated with in utero infection and inflammation. We used an ovine model of in utero infection to ask if exposure to Ureaplasma serovar 3 (UP) modulated the response of the fetal skin to LPS.
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Ureaplasmas are the microorganisms most frequently isolated from the amniotic fluid of pregnant women and can cause chronic intrauterine infections. These tiny bacteria are thought to undergo rapid evolution and exhibit a hypermutatable phenotype; however, little is known about how ureaplasmas respond to selective pressures in utero. Using an ovine model of chronic intra-amniotic infection, we investigated if exposure of ureaplasmas to sub-inhibitory concentrations of erythromycin could induce phenotypic or genetic indicators of macrolide resistance. At 55 days gestation, 12 pregnant ewes received an intra-amniotic injection of a non-clonal, clinical U. parvum strain, followed by: (i) erythromycin treatment (IM, 30 mg/kg/day, n=6); or (ii) saline (IM, n=6) at 100 days gestation. Fetuses were then delivered surgically at 125 days gestation. Despite injecting the same inoculum into all ewes, significant differences between amniotic fluid and chorioamnion ureaplasmas were detected following chronic intra-amniotic infection. Numerous polymorphisms were observed in domain V of the 23S rRNA gene of ureaplasmas isolated from the chorioamnion (but not the amniotic fluid), resulting in a mosaic-like sequence. Chorioamnion isolates also harboured the macrolide resistance genes erm(B) and msr(D) and were associated with variable roxithromycin minimum inhibitory concentrations. Remarkably, this variability occurred independently of exposure of ureaplasmas to erythromycin, suggesting that low-level erythromycin exposure does not induce ureaplasmal macrolide resistance in utero. Rather, the significant differences observed between amniotic fluid and chorioamnion ureaplasmas suggest that different anatomical sites may select for ureaplasma sub-types within non-clonal, clinical strains. This may have implications for the treatment of intrauterine ureaplasma infections.