1.7 Nicholas Cave, Assistant Legal Counsel, University of Missouri

https://bluetigercommons.lincolnu.edu/lgaines_sec2/1006/thumbnail.jpg

1.6 Lloyd Hogsett, University of Missouri Legal Counsel

By March, 1936, the University of Missouri formally rejected Gaines because Missouri law would not permit a person of African descent to enter a white school. Within three weeks, the NAACP petitioned the court asking the University of Missouri to open its doors to Gaines on the grounds that it was the only public law school in Missouri.

2.3 University of Missouri building

The university’s defense, led by William Hogsett, countered that the University was bound by law to reject Gaines’ application and stated that Lincoln University had to provide higher education for Negroes. This is the point that Houston wanted the court to address. Houston got Canada to admit the only students he would bar would be of African descent. Hogsett, on the other hand, was unable to unnerve young Mr. Gaines with speculation that the NAACP had put him up to applying at MU. Gaines replied,” No, that is my idea; about the [law] suit.”

3.3 University of Missouri awarded a law degree to Lloyd Gaines in 2006

In 2006, a law degree was posthumously awarded to Lloyd and accepted by his nephew, George Gaines.

3.2 Lloyd L. Gaines/Marian O'Fallon Oldham Black Culture Center at University of Missouri

Lloyd Gaines’ memory has been honored most notably by the University of Missouri. In 1995, a law scholarship in his name was established at the institution. Also, in 2001, MU opened the Gaines/Oldham Black Culture at MU which shares his name.

3.4 University of Missouri Doctor of Law Degree to Lloyd Lionel Gaines

On May 13, 2006, University of Missouri awarded Lloyd Gaines Doctor of Law degree.

Soldiers' dream continued : a pictorial history of Lincoln University of Missouri

Pictorial history of Lincoln University of Missouri from 1866-1980s.

Soldiers' dream : a centennial history of Lincoln University of Missouri

A Pictorial History of Lincoln University from 1866-1966.

Record of service, 1914-1918, University of British Columbia, McGill British Columbia, Vancouver college.

Mode of access: Internet.

Research bulletin / University of Missouri, College of Agriculture, Agricultural Experiment Station.

Mode of access: Internet.

Public lectures delivered in the chapel of the University of the State of Missouri,

Mode of access: Internet.

Report of the committee on the reorganization and enlargement of the University of the state of Missouri, presented to the Board of curators, at their meeting, December 20, 1870.

Mode of access: Internet.

Soil survey laboratory data and descriptions for some soils of Arkansas, Louisiana, Missouri /

Mode of access: Internet.

Interview with Dr. Young-Ki Paik, President of the Human Proteome Organization (HUPO): Pharmacoproteomics and the approaching wave of “Proteomics Diagnostics”

Dr. Young-Ki Paik directs the Yonsei Proteome Research Center in Seoul, Korea and was elected as the President of the Human Proteome Organization (HUPO) in 2009. In the December 2009 issue of the Current Pharmacogenomics and Personalized Medicine (CPPM), Dr. Paik explains the new field of pharmacoproteomics and the approaching wave of “proteomics diagnostics” in relation to personalized medicine, HUPO’s role in advancing proteomics technology applications, the HUPO Proteomics Standards Initiative, and the future impact of proteomics on medicine, science, and society. Additionally, he comments that (1) there is a need for launching a Gene-Centric Human Proteome Project (GCHPP) through which all representative proteins encoded by the genes can be identified and quantified in a specific cell and tissue and, (2) that the innovation frameworks within the diagnostics industry hitherto borrowed from the genetics age may require reevaluation in the case of proteomics, in order to facilitate the uptake of pharmacoproteomics innovations. He stresses the importance of biological/clinical plausibility driving the evolution of biotechnologies such as proteomics,instead of an isolated singular focus on the technology per se. Dr. Paik earned his Ph.D. in biochemistry from the University of Missouri-Columbia and carried out postdoctoral work at the Gladstone Foundation Laboratories of Cardiovascular Disease, University of California at San Francisco. In 2005, his research team at Yonsei University first identified and characterized the chemical structure of C. elegans dauer pheromone (daumone) which controls the aging process of this nematode. He is interviewed by a multidisciplinary team specializing in knowledge translation, technology regulation, health systems governance, and innovation analysis.

Early transplantation of human immature dental pulp stem cells from baby teeth to golden retriever muscular dystrophy (GRMD) dogs: Local or systemic?

Background:The golden retriever muscular dystrophy (GRMD) dogs represent the best available animal model for therapeutic trials aiming at the future treatment of human Duchenne muscular dystrophy (DMD). We have obtained a rare litter of six GRMD dogs (3 males and 3 females) born from an affected male and a carrier female which were submitted to a therapeutic trial with adult human stem cells to investigate their capacity to engraft into dogs muscles by local as compared to systemic injection without any immunosuppression. Methods Human Immature Dental Pulp Stem Cells (hIDPSC) were transplanted into 4 littermate dogs aged 28 to 40 days by either arterial or muscular injections. Two non-injected dogs were kept as controls. Clinical translation effects were analyzed since immune reactions by blood exams and physical scores capacity of each dog. Samples from biopsies were checked by immunohistochemistry (dystrophin markers) and FISH for human probes. Results and Discussion We analyzed the cells' ability in respect to migrate, engraftment, and myogenic potential, and the expression of human dystrophin in affected muscles. Additionally, the efficiency of single and consecutive early transplantation was compared. Chimeric muscle fibers were detected by immunofluorescence and fluorescent in situ hybridisation (FISH) using human antibodies and X and Y DNA probes. No signs of immune rejection were observed and these results suggested that hIDPSC cell transplantation may be done without immunosuppression. We showed that hIDPSC presented significant engraftment in GRMD dog muscles, although human dystrophin expression was modest and limited to several muscle fibers. Better clinical condition was also observed in the dog, which received monthly arterial injections and is still clinically stable at 25 months of age. Conclusion Our data suggested that systemic multiple deliveries seemed more effective than local injections. These findings open important avenues for further researches.