The Pennsylvania Turnpike Commission's Incident Management Team.

Transportation Department, Washington, D.C.

Examining congestion pricing implementation issues : summary of proceedings, Congestion Pricing Symposium, June 10-12, 1992.

"Publication no. FHWA-PL-93-008"--P. 4 of cover.

Exploring the role of pricing as a congestion management tool : summary of proceeedings : Seminar on the Application of Pricing Principles to Congestion Management.

"FHWA-PL-92-012."

A roadmap for the future : recommendations and guiding principles for Illinois Tollway decision-making /

"October 2010"--Cover.

Annual report /

Title from cover.

Annual report /

Cover title.

I-355 extension update.

Includes an annoucement that the Illinois Dept. of Transportation, in cooperation with the Illinois State Toll Highway Authority, will be performing additional studies in support of the extension of I-355 through Will County, Illinois.

Illinois tollway annual report.

Mode of access: Internet.

Illinois Tollway.

Mode of access: Internet.

The abolition of the toll-bar system, and the best means of making and maintaining the public roads : a discussion at general meeting of the Scottish Chamber of Agriculture, held at Edinburgh, November 13, 1866...--

Mode of access: Internet.

Toll facilities in the United States : bridges, roads, tunnels, ferries.

Mode of access: Internet.

Energy consumption and intensity of toll highway transport in Spain

We estimate the energy consumption of toll highway transport on a number of Spanish roads. Regression parameters are balanced according to coefficients from an empirical analysis based on survey data by vehicle type. The mean energy consumption and subsequent CO2 emissions on the toll highway sections are estimated as 1895 MJ/h/lane-km and 0.15 tCO2 eq./h/lane-km, values that increase to 2644 and 0.22 when energy and carbon emissions of transport infrastructure are considered based on the life cycle energy consumption for toll highway construction and use. If the energy intensity of infrastructure construction is allocated to the users according to traffic, it is much higher for motorcycles than for cars, and is significantly lower for articulated trucks than for vans.

Roads from Rome /

"Three of the papers ... have already appeared in the Atlantic monthly."

The laws of trade applied to the determination of the most advantageous fare for passengers on rail roads.

[With his Popular exposition of the incorrectness of the tariffs of toll in use on the public improvements of the United States. Philadelphia, 1839]

Toll-like Receptor 4 Activation Promotes Cardiac Arrhythmias By Decreasing The Transient Outward Potassium Current (ito) Through An Irf3-dependent And Myd88-independent Pathway.

Cardiac arrhythmias are one of the main causes of death worldwide. Several studies have shown that inflammation plays a key role in different cardiac diseases and Toll-like receptors (TLRs) seem to be involved in cardiac complications. In the present study, we investigated whether the activation of TLR4 induces cardiac electrical remodeling and arrhythmias, and the signaling pathway involved in these effects. Membrane potential was recorded in Wistar rat ventricle. Ca(2+) transients, as well as the L-type Ca(2+) current (ICaL) and the transient outward K(+) current (Ito), were recorded in isolated myocytes after 24 h exposure to the TLR4 agonist, lipopolysaccharide (LPS, 1 μg/ml). TLR4 stimulation in vitro promoted a cardiac electrical remodeling that leads to action potential prolongation associated with arrhythmic events, such as delayed afterdepolarization and triggered activity. After 24 h LPS incubation, Ito amplitude, as well as Kv4.3 and KChIP2 mRNA levels were reduced. The Ito decrease by LPS was prevented by inhibition of interferon regulatory factor 3 (IRF3), but not by inhibition of interleukin-1 receptor-associated kinase 4 (IRAK4) or nuclear factor kappa B (NF-κB). Extrasystolic activity was present in 25% of the cells, but apart from that, Ca(2+) transients and ICaL were not affected by LPS; however, Na(+)/Ca(2+) exchanger (NCX) activity was apparently increased. We conclude that TLR4 activation decreased Ito, which increased AP duration via a MyD88-independent, IRF3-dependent pathway. The longer action potential, associated with enhanced Ca(2+) efflux via NCX, could explain the presence of arrhythmias in the LPS group.