Rouen, France, 1943 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Rouen : city plan. 1st ed.-AMS 1. It was published by the United States Army Map Service in 1943. Scale 1:12,500. Covers Rouen, France. The image inside the map neatline is georeferenced to the surface of the earth and fit to the 'European Datum 1950 UTM Zone 31N' coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as roads, railroads and stations, drainage, built-up areas and selected buildings and industries, parks, wharves, docks, city district boundaries, and more. This layer is part of a selection of digitally scanned and georeferenced historic maps from The Harvard Map Collection as part of the Imaging the Urban Environment project. Maps selected for this project represent major urban areas and cities of the world, at various time periods. These maps typically portray both natural and manmade features at a large scale. The selection represents a range of regions, originators, ground condition dates, scales, and purposes.

Strasbourg, France, City Planning, 1880 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Bebauungsplan für die Erweiterung der Stadt Strassburg. It was published by Druck und Verlag R. Schultz & Cie. in 1880. Scale 1:5,000. Covers Strasbourg, France. Map in German. The image inside the map neatline is georeferenced to the surface of the earth and fit to the 'European Datum 1950 UTM Zone 32N' coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows development plans for the expansion of the city of Strasbourg. It includes features such as existing and proposed roads (with measurements), railroads and stations, drainage, built-up areas and selected buildings, fortification, ground cover, parks, and more. This layer is part of a selection of digitally scanned and georeferenced historic maps from The Harvard Map Collection as part of the Imaging the Urban Environment project. Maps selected for this project represent major urban areas and cities of the world, at various time periods. These maps typically portray both natural and manmade features at a large scale. The selection represents a range of regions, originators, ground condition dates, scales, and purposes.

Strasbourg, France, City Planning, 1910 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Plan der Stadt Strassburg : aufgestellt nach dem amtlichen Bebauungsplan. It was published by W. Heinrich in 1910. Scale 1:7,500. Covers Strasbourg, France. Map in German. The image inside the map neatline is georeferenced to the surface of the earth and fit to the 'European Datum 1950 UTM Zone 32N' coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows development plans for the expansion of the city of Strasbourg. It includes features such as existing and proposed roads, railroads and stations, street-railroads, drainage, built-up areas and selected buildings, ground cover, parks, city district boundaries, and more. Includes black pen-and-ink manuscript additions and type-script paper pasted over map in English; red and yellow lines showing the public lands & buildings & lands owned by municpality. This layer is part of a selection of digitally scanned and georeferenced historic maps from The Harvard Map Collection as part of the Imaging the Urban Environment project. Maps selected for this project represent major urban areas and cities of the world, at various time periods. These maps typically portray both natural and manmade features at a large scale. The selection represents a range of regions, originators, ground condition dates, scales, and purposes.

La Gironde Rivière Area, Bordeaux, France, ca. 1910 (Image 2 of 2) (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Plan de Bordeaux. It was published ca. 1910. Scale 1:10,000. Covers La Gironde Rivière area, Bordeaux, France. This layer is image 2 of 2 total images of the two sheet source map, representing the northern portion of the map. Map in French. The image inside the map neatline is georeferenced to the surface of the earth and fit to the 'European Datum 1950 UTM 30N' projected coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as roads, railroads, drainage, built-up areas and selected buildings and industries, docks and wharves, and more. Includes manuscript additions. This layer is part of a selection of digitally scanned and georeferenced historic maps from The Harvard Map Collection as part of the Imaging the Urban Environment project. Maps selected for this project represent major urban areas and cities of the world, at various time periods. These maps typically portray both natural and manmade features at a large scale. The selection represents a range of regions, originators, ground condition dates, scales, and purposes.

Rouen, France, 1884 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Rouen. It was published by gravé et imprimé par Wagner & Debes in 1884. Scale 1:20,000. Map in French. Covers Rouen, France.The image inside the map neatline is georeferenced to the surface of the earth and fit to the European Datum 1950, Universal Transverse Mercator (UTM) Zone 31N projected coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as roads, railroads and stations, drainage, built-up areas and selected buildings and industries, docks, and more. Relief shown by hachures.This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of originators, ground condition dates, scales, and map purposes.

Lyon, France, ca. 1910 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Noveau plan topographique de la ville Lyon : comprenant et indiquant toutes les améliorations en projet et en voie d'exécution, par l'agence Fournier, Lyon. It was published by Fournier ca. 1910. Scale [ca. 1:10,000]. The image inside the map neatline is georeferenced to the surface of the earth and fit to the European Datum 1950, Universal Transverse Mercator (UTM) Zone 31N projected coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as roads, railroads and stations, drainage, built-up areas and selected buildings, fortification, property boundaries, parks, and more. Relief shown by hachures.This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of originators, ground condition dates, scales, and map purposes.

Official map publications; a historical sketch, and a bibliographical handbook of current maps and mapping services in the United States, Canada, Latin America, France, Great Britain, Germany, and certain other countries,

"Classification, cataloging, and care of maps": p. 282-295; "Tentative map classification outline by subject": p. 297-308; "Map classification outline by areas": p. 309-311.

Prospectus of the Buffalo and Washington railway company : with maps of its route and connections with other railroads in Pennsylvania, New Jersey and Maryland. May 1, 1865.

Mode of access: Internet.

Heat maps for aggregating bioacoustic annotations

In our large library of annotated environmental recordings of animal vocalizations, searching annotations by label can return thousands of results. We propose a heat map of aggregated annotation time and frequency bounds, maintaining the shape of the annotations as they appear on the spectrogram. This compactly displays the distribution of annotation bounds for the user's query, and allows them to easily identify unusual annotations. Key to this is allowing zero values on the map to be differentiated from areas where there are single annotations.

Genetics of path lengths in brain connectivity networks: HARDI-based maps in 457 adults

Brain connectivity analyses are increasingly popular for investigating organization. Many connectivity measures including path lengths are generally defined as the number of nodes traversed to connect a node in a graph to the others. Despite its name, path length is purely topological, and does not take into account the physical length of the connections. The distance of the trajectory may also be highly relevant, but is typically overlooked in connectivity analyses. Here we combined genotyping, anatomical MRI and HARDI to understand how our genes influence the cortical connections, using whole-brain tractography. We defined a new measure, based on Dijkstra's algorithm, to compute path lengths for tracts connecting pairs of cortical regions. We compiled these measures into matrices where elements represent the physical distance traveled along tracts. We then analyzed a large cohort of healthy twins and show that our path length measure is reliable, heritable, and influenced even in young adults by the Alzheimer's risk gene, CLU.

Atlas de France Vinicole, 1946

An atlas of wines of France from a series. This particular Atlas is from the year 1946 and includes photographs, maps and descriptions. The descriptions are in French, English and Italian.

Use of self-organizing maps and molecular descriptors to predict the cytotoxic activity of sesquiterpene lactones

Some sesquiterpene lactones (SLs) are the active compounds of a great number of traditionally medicinal plants from the Asteraceae family and possess considerable cytotoxic activity. Several studies in vitro have shown the inhibitory activity against cells derived from human carcinoma of the nasopharynx (KB). Chemical studies showed that the cytotoxic activity is due to the reaction of alpha,beta-unsaturated carbonyl structures of the SLs with thiols, such as cysteine. These studies support the view that SLs inhibit tumour growth by selective alkylation of growth-regulatory biological macromolecules, such as key enzymes, which control cell division, thereby inhibiting a variety of cellular functions, which directs the cells into apoptosis. In this study we investigated a set of 55 different sesquiterpene lactones, represented by 5 skeletons (22 germacranolides, 6 elemanolides, 2 eudesmanolides, 16 guaianolides and nor-derivatives and 9 pseudoguaianolides), in respect to their cytotoxic properties. The experimental results and 3D molecular descriptors were submitted to Kohonen self-organizing map (SOM) to classify (training set) and predict (test set) the cytotoxic activity. From the obtained results, it was concluded that only the geometrical descriptors showed satisfactory values. The Kohonen map obtained after training set using 25 geometrical descriptors shows a very significant match, mainly among the inactive compounds (similar to 84%). Analyzing both groups, the percentage seen is high (83%). The test set shows the highest match, where 89% of the substances had their cytotoxic activity correctly predicted. From these results, important properties for the inhibition potency are discussed for the whole dataset and for subsets of the different structural skeletons. (C) 2008 Elsevier Masson SAS. All rights reserved.