85 resultados para RIT


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reunis et composés par Émile Jonas

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A aprendizagem das competências da leitura e da escrita é uma das primeiras conquistas que as crianças realizam no 1.º Ciclo do Ensino Básico. Neste âmbito é essencial conhecer e dominar todos os processos e métodos envolvidos nesta aprendizagem para a adequação do ensino e a prevenção das dificuldades de aprendizagem. Esta Dissertação de Mestrado em Ciências da Educação na especialidade de Educação Especial: Domínio Cognitivo-Motor visa descobrir a metodologia de ensino de leitura e escrita que mais se adequa às crianças disléxicas, disgráficas ou com atraso na aprendizagem da leitura e escrita, valorizando os Meios Educativos Jean-Qui-Rit e as efetivas vantagens na sua aplicação. Em suma é um trabalho que visa, para além de uma análise aprofundada de vários conceitos ligados à temática, expor todos os processos e métodos de iniciação à leitura e escrita existentes, bem como demonstrar a metodologia mais fiável a aplicar com os alunos disléxicos, disgráficos ou com atraso na leitura e escrita e também facultar meios, recursos, estratégias e instrumentos de avaliação para trabalhar a reeducação com este tipo de discentes.

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Mode of access: Internet.

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Mode of access: Internet.

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Mode of access: Internet.

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Mode of access: Internet.

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Current guidelines have advised against the performance of (131)I-iodide diagnostic whole body scintigraphy (dxWBS) to minimize the occurrence of stunning, and to guarantee the efficiency of radioiodine therapy (RIT). The aim of the study was to evaluate the impact of stunning on the efficacy of RIT and disease outcome. This retrospective analysis included 208 patients with differentiated thyroid cancer managed according to a same protocol and followed up for 12-159 months (mean 30 ± 69 months). Patients received RIT in doses ranging from 3,700 to 11,100 MBq (100 mCi to 300 mCi). Post-RIT-whole body scintigraphy images were performed 10 days after RIT in all patients. In addition, images were also performed 24-48 hours after therapy in 22 patients. Outcome was classified as no evidence of disease (NED), stable disease (SD) and progressive disease (PD). Thyroid stunning occurred in 40 patients (19.2%), including 26 patients with NED and 14 patients with SD. A multivariate analysis showed no association between disease outcome and the occurrence of stunning (p = 0.3476). The efficacy of RIT and disease outcome do not seem to be related to thyroid stunning.

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OBJECTIVE: Evaluate the efficacy of cumulative doses (CDs) of 131I-iodide therapy (RIT) in differentiated thyroid cancer (DTC). SUBJECTS AND METHODS: The probability of progressive disease according to CDs was evaluated in patients < 45 years old and > 45 years old and correlated to tumor-node-metastasis (TNM), thyroglobulin values, histological types and variants, age, and zduration of the disease. RESULTS: At the end of a follow-up period of 69 ± 56 months, 85 out of 150 DTC patients submitted to fixed doses RIT had no evidence of disease, 47 had stable disease and 18 had progressive disease. Higher CDs were used in the more aggressive variants (p < 0.0001), higher TNM stages (p < 0.0001), and follicular carcinomas (p = 0.0034). Probability of disease progression was higher with CDs > 600 mCi in patients > 45 years old and with CDs > 800 mCi in patients < 45 years. CONCLUSION: Although some patients may still respond to high CDs, the impact of further RIT should be carefully evaluated and other treatment strategies may be warranted.