995 resultados para Protéine de stress-72 (HSP-72)


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This study was undertaken to examine the main and interactive effects of work stress and work control on levels of adjustment. Work stress, behavioral control, and informational control were manipulated in an experimental setting in which participants (N = 192) completed an in-basket activity. Although minimal support was found for the main and interactive effects of objective work stress, behavioral control, and informational control on adjustment, analyses involving the subjective measures of these variables revealed strong support for the proposal that work stress, behavioral control, and informational control would exert main effects on adjustment. There was also evidence that subjective levels of behavioral control buffered the negative effects of subjective work stress on positive mood, subjective task performance, and task satisfaction.

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This work investigates the academic stress and mental health of Indian high school students and the associations between various psychosocial factors and academic stress. A total of190 students from grades 11 and 12 (mean age: 16.72 years) from three government-aided and three private schools in Kolkata India were surveyed in the study. Data collection involved using a specially designed structured questionnaire as well as the General Health Questionnaire. Nearly two-thirds (63.5%) of the students reported stress due to academic pressure – with no significant differences across gender, age, grade, and several other personal factors. About two-thirds (66%) of the students reported feeling pressure from their parents for better academic performance. The degree of parental pressure experienced differed significantly across the educational levels of the parents, mother’s occupation, number of private tutors, and academic performance. In particular, children of fathers possessing a lower education level (non-graduates) were found to be more likely to perceive pressure for better academic performance. About one-thirds (32.6%) of the students were symptomatic of psychiatric caseness and 81.6% reported examination-related anxiety. Academic stress was positively correlated with parental pressure and psychiatric problems, while examination-related anxiety also was positively related to psychiatric problems. Academic stress is a serious issue which affects nearly two thirds of senior high school students in Kolkata. Potential methods for combating the challenges of academic pressure are suggested.

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Background: The gene encoding for uncoupling protein-1 (UCP1) is considered to be a candidate gene for type 2 diabetes because of its role in thermogenesis and energy expenditure. The objective of the study was to examine whether genetic variations in the UCP1 gene are associated with type 2 diabetes and its related traits in Asian Indians. Methods: The study subjects, 810 type 2 diabetic subjects and 990 normal glucose tolerant (NGT) subjects, were chosen from the Chennai Urban Rural Epidemiological Study (CURES), an ongoing population-based study in southern India. The polymorphisms were genotyped using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. Linkage disequilibrium (LD) was estimated from the estimates of haplotypic frequencies. Results: The three polymorphisms, namely -3826A -> G, an A -> C transition in the 5'-untranslated region (UTR) and Met229Leu, were not associated with type 2 diabetes. However, the frequency of the A-C-Met (-3826A -> G-5'UTR A -> C-Met229Leu) haplotype was significantly higher among the type 2 diabetic subjects (2.67%) compared with the NGT subjects (1.45%, P < 0.01). The odds ratio for type 2 diabetes for the individuals carrying the haplotype A-C-Met was 1.82 (95% confidence interval, 1.29-2.78, P = 0.009). Conclusions: The haplotype, A-C-Met, in the UCP1 gene is significantly associated with the increased genetic risk for developing type 2 diabetes in Asian Indians.

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English summary: On snowmelt and water balance during snowmelt period in Pääjärvi representative basin in 1970-72

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A 0.9 kb double stranded cDNA of foot and mouth disease virus (FMDV) Type Asia 1, 63/72 was cloned in an expression vector, pUR222. A protein of 38 kd was produced by the clone which reacted with the antibodies raised against the virus. A 20 kd protein which may be derived from the 38 kd protein contained the antigenic epitopes of the protein VP1 of the virus. Injection of 10-20 micrograms of the partially purified 38 and 20 kd proteins or a lysate of cells containing 240 micrograms of the proteins elicited high titers of FMDV specific antibodies in guinea pigs and cattle respectively. Also, at these concentrations, the proteins protected 5 of 8 guinea pigs and 3 of 8 cattle when challenged with a virulent virus.

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Regular vaccinations with potent vaccine, in endemic countries and vaccination to live in non-endemic countries are the methods available to control foot-and-mouth disease. Selection of candidate vaccine strain is not only cumbersome but the candidate should grow well for high potency vaccine preparation. Alternative strategy is to generate an infectious cDNA of a cell culture-adapted virus and use the replicon for development of tailor-made vaccines. We produced a chimeric `O' virus in the backbone of Asia 1 and studied its characteristics. The chimeric virus showed high infectivity titre (>10(10)) in BHK 21 cell lines, revealed small plague morphology and there was no cross reactivity with antiserum against Asia I. The virus multiplies rapidly and reaches peak at 12 h post infection. The vaccine prepared with this virus elicited high antibody titres.

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Contenido: Ponencias. Escrituras del viaje en la Edad Media hispánica: Viajeros de tierras extrañas : esposos sobrenaturales en la leyenda del Caballero del Cisne en La gran conquista de Ultramar / María Eugenia Alcatena -- Utopía : relato de un viaje desde el medioevo al renacimiento / Pablo A. Blanco González -- El Libro de Alexandre : un repositorio de saber geográfico / Penélope Marcela Fernández Izaguirre -- Peregrinación a la cibdat de gygantes : configuración del imaginario geográfico bíblico en La fazienda de Ultramar / Melisa Laura Marti -- Estudios de literatura española medieval: La configuración heroica del personaje de Enalviello en la Crónica de la población de Ávila / Manuel Abeledo -- "Et avié una viña rica, de mejor non nos cala" : la representación del palacio de Poro y la viña áurea en el Libro de Alexandre, diálogos intertextuales y funciones literarias / Gerardo Altamirano Meza -- Algunas cuestiones textuales en torno al Liber Mariae de Juan Gil de Zamora (ca. 1241-1318) / Olga Soledad Bohdziewicz -- Literatura hispanorromance primigenia : la glosa conoajutorio del Codex Aemilianensis 60 / María Gimena del Río Riande -- Más sobre Ayala narrador en la crónica de Enrique III / Jorge N. Ferro -- La construcción de Alfonso XI como héroe épico en el Poema de Alfonso Onceno : el caso del asesinato de don Juan el tuerto / Erica Janin -- "Y vino a consentir, aunque no por su voluntad, que tuviese sus ayuntamientos libidinosos con ella" : sobre los raptos femeninos ejecutados por animales en la literatura española / Lucía Orsanic -- Acerca del Troço de la corónica del rey don Enrique el doliente del manuscrito BNM 1530 / Pablo Enrique Saracino -- Los nombres de la ley : identidad y autoridad en lafazaña castellana / Maximiliano A. Soler Bistué -- Teología mística de Gonzalo de Berceo / Aquilino Suárez Pallasá -- El Viejo, el Amor y la Hermosa como texto espectacular / Lillian vonder Walde Moheno -- Reescritura de refranes sobre la apariencia y realidad el El Criticón de Baltasar Gracián / Verónica Marcela Zalba -- Reseñas

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The Department of Natural Resources, Bureau of Geology, is publishing as its Information Circular No. 85 the report entitled, "Water Levels in Artesian and Non-Artesian Aquifers of Florida, 1971-72," by Henry G. Healy, of the U. S. Geological Survey. In order to prevent future shortages developing from increasing demands, the present supplies of ground water must be properly appraised before they can be effectively utilized. Records of trends and fluctuations of ground water have long formed a basis for such an appraisal. (105 page document)

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(PDF contains 5 pages.)