O efeito da ciclosporina-A na osseointegração

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Efeito do Diabetes mellitus e da insulinoterapia na osseointegração estabelecida ao redor de implantes instalados em tíbia de ratos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Utilização do extrato de óleo insaponificável de abacte e soja na osseointegração. Avaliação biomecânca, radiográfica, histológica e histomorfométrica em ratos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Influência de uma superfície modificada por fluoretos na osseointegração de implantes dentais em ratos diabéticos

Pós-graduação em Odontologia - FOAR

Utilização sistêmica de estrôncio não radioativo como potencializador da osseointegração de implantes: avaliação biomeânica, microtomográfica e histomorfométrica em ratos

Pós-graduação em Odontologia - FOAR

Efeito de três sistemas de osteotomia - ultrassom cirúrgico, laser Er, Cr: YSGG e sistema rotatório - sobre o processo de osseointegração e reparo de defeitos ósseos em tíbia de ratos: estudo histomorfométrico, imuno-histoquímico e biomecânico

Pós-graduação em Odontologia - FOAR

Efeito do extrato insaponificável de abacate e soja na doença periodontal induzida, na osseointegração de implantes e no reparo de defeitos críticos de calvaria de ratos

Pós-graduação em Odontologia - FOAR

Efeito da aPDT na osseointegração de implantes em alvéolos contaminados

Objective: The aim of this study is to evaluate by histometric and immunohistochemistry analysis the effects of antimicrobial photodynamic therapy (aPDT) in alveolar prior to placement of mini-implants in animals with or without induced periodontal disease. Material and method: Thirty-two rats were used. Periodontal disease (PD) was induced by ligature in the lower left first molar. After 7 days of PD evolution, it was performed removal of the ligature and extraction of the left lower first molars in all animals. Thus, animals were divided into 2 groups (n=16) according to the treatments in the dental alveolus before immediate implant installation: MD (control) : mechanical debridement (MD), irrigation with 1 ml of saline solution followed by implant installation; aPDT- MD, irrigation with 1 ml of Toluidine Blue-O and low intensity laser (LLLT) and implant installation. Eight animals from each group were euthanized at 15 and 30 days after the installation of mini-implants. Specimens were processed for histologic, immunohistochemical and histometric analysis. The histometric data were processed for statistical analysis (Kruskall-Wallis and Dunn test; p <0.05). Result: In treatment analysis, results indicated that there was a greater BIC in implants installed in uncontaminated alveolus treated with a PDT ( p<0,05) and greater imuno-reactivity to OPG in bone issue treated with aPDT. Conclusion: The aPDT proved to be effective in bone loss control in no contaminated area and it has increased the bone loss and metabolic activity in alveolus irradiated prior to implant installation.

Aspectos biológico-celulares da osseointegração baseados nas superfícies de implantes

Osseointegration involves a cascade of biological events, which can be accelerated by modifying the micro and/or nanometric topography of dental implant surfaces. Considering that different treatment types modify the titanium surface giving it a more pronounced rough topography, and physicochemical changes that appear to positively influence the osseointegration process, a literature review was made on the main types of surface treatments and their influence on the biological and cellular aspects of osseointegration, with publications dating from 1969 until the present moment. Although the precise role of the implant surface on the osseointegration of dental implants is not completely clear, the specific effects of implant surface on bone regeneration, initial kinetics, and evolution of mechanical properties have shown to be quite promising. Thus, based on dental implant surface modifications, osseointegration can be defined as a process by which rigid asymptomatic fixation of an alloplastic material can be achieved and kept in close contact with bone tissue, being resistant to early and late functional loads. This process can be modulated by an appropriate treatment of the alloplastic material surface.

Impacto do controle glicêmico sobre as complicações associadas ao diabetes mellitus na osseointegração

The increased prevalence of diabetic individuals has become a public health problem. Diabetes Mellitus is a metabolic disorder characterized by an increase in plasma glucose levels. It impairs the physiological equilibrium in utilization of carbohydrate by tissues. The persistent hyperglycemia can produce deleterious effects on bone formation due the microvascular complication. The present paper reviews the bibliography linking the impact of glycemic control at complications associated at diabetes mellitus on osseointegration. In experimental models of diabetes it was observed a reduced level of bone-implant contact. This failure can be reduced by means of hyperglycemia control. Also, several studies point the beneficial effect of coated implant on osseointegration process. It is necessary to take special care into account for the placement of implants in diabetic patient and improve the percentages of implant survival. A rigorous control of plasma glycaemia, together with other measures, like as absence of chronic complications, good oral hygiene and regular medical follow-up has been related to rising the percentages of successful in diabetic patients.

Osseointegração de implantes instalados sem estabilidade primária: o papel dos materiais à base de fibrina e fosfato de cálcio

When implants are installed immediately after tooth extraction may occur anchoring primary decreased, delay or failure of osseointegration process. This occurs because of the large interface between the surrounding walls of the socket and the surface of the implant. For reconstruction, replacement or filling of bone defects the solution can be obtained with the use of autogenous, heterogenous or allogeneic bone grafts. However, these grafts suffer certain drawbacks, particularly a high rate of donor site morbidity, limited amounts of available bone, and the additional operative time required for harvest. For these reasons, intensive efforts have been directed toward developing alternative substances for to either augment or substitute. In this paper, we will examine some of the commonly used materials : fibrin and calcium phosphate.

Efeito na osseointegração de um novo método de nanotexturização de superfície de implantes através de anodização

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Influência da quimioterapia com 5-Fluorouracil na osseointegração de implantes instalados em tíbias de ratos: avaliação biomecânica, microtomográfica, histomorfométrica, histoquímica e imunoistoquímica

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Influência da quimioterapia com 5-Fluorouracil na osseointegração de implantes instalados em tíbias de ratos: avaliação biomecânica, microtomográfica, histomorfométrica, histoquímica e imunoistoquímica

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)