The doctrine of the Russian Church : being the primer or spelling book, the shorter and longer catechisms, and a treatise on the duty of parish priests. /

Mode of access: Internet.

Not for personal gratification, or for contention, or to look down on others, or for convenience, reputation, or power : Cultura Animi in Bacon’s 1605 Apology for the proficiency and advancement of learning

This paper examines the apology for the life of the mind Francis Bacon gives in Book I of his 1605 text The Advancement of Learning. Like recent work on Bacon led by the ground-breaking studies of Corneanu, Harrison and Gaukroger, I argue that Bacon’s conception and defence of intellectual inquiry in this extraordinary text is framed by reference to the classical model, which had conceived and justified philosophising as a way of life or means to the care of the inquirer’s soul or psyche. In particular, Bacon’s proximities and debts to the Platonic Apology and Cicero’s defence of intellectual pursuits in Rome are stressed, alongside the acuity and eloquence of Bacon’s descriptions of the intellectual virtues and their advertised contributions to the theologically and civically virtuous life.

Magnetisation of 2.6T in Gadolinium Thin Films

There is renewed interest in rare-earth elements and gadolinium in particular for a range of studies in coupling physics and applications. However, it is still apparent that synthesis impacts understanding of the intrinsic magnetic properties of thin gadolinium films, particularly for thicknesses of topicality. We report studies on 50nm thick nanogranular polycrystalline gadolinium thin films on SiO2 wafers that demonstrate single-crystal like behavior. The maximum in-plane saturation magnetization at 4K was found to be 4pMS4K = (2.61±0.26)T with a coercivity of HC4K = (160±5)Oe. A maximum Curie point of TC = (293±2)K was measured via zero-field-cooled - field-cooled magnetization measurements in close agreement with values reported in bulk single crystals. Our measurements revealed magnetic transitions at T1 = (12±2)K (as deposited samples) and T2 = (22±2)K (depositions on heated substrates) possibly arising from the interaction of paramagnetic fcc grains with their ferromagnetic hcp counterparts.

Effects of soil and foliar application of soluble silicon on mineral nutrition, gas exchange, and growth of potato plants

Silicon can alleviate biotic and abiotic stresses in several crops, and it has beneficial effects on plants under nonstressed conditions. However, there is still doubt about foliar-applied Si efficiency and Si effects on mineral nutrition, physiological processes, and growth of potato (Solanum tuberosum L.) plants under wellwatered conditions. The objective of this study was to evaluate the effect of soil and foliar application of soluble Si on Si accumulation, nutrients, and pigments concentration as well as gas exchange and growth of potato plants. The experiment was conducted under greenhouse conditions in pots containing 35 dm3 of a Typic Acrortox soil. The treatments consisted of a control (no Si application), soil application of soluble Si (50 mg dm-3 Si), and foliar application of soluble Si (three sprays of 1.425 mM Si water solution, prepared with a soluble concentrate stabilized silicic acid), with eight replications. Both soil and foliar application of Si resulted in higher Si accumulation in the whole plant. Foliar application of Si resulted in the greatest Si concentration in leaves, and soil application increased Si concentration in leaves, stems, and roots. Silicon application, regardless of the application method, increased leaf area, specific leaf area, and pigment concentration (chlorophyll a and carotenoids) as well as photosynthesis and transpiration rates of wellwatered potato plants. However, only soil application increased P concentration in leaves and dry weight of leaves and stems. © Crop Science Society of America.

Undergraduate Scholarship in the College of Arts and Sciences 2004 Book of Abstracts

In his work entitled The Advancement of Learning (1605), Francis Bacon expresses the need for students and their teachers to push beyond current knowledge by testing accepted theories, developing new paradigms, and discovering new information. The abstracts in this booklet are clear examples of how students and faculty in the College of Arts and Sciences are advancing knowledge in a variety of disciplines. From the analysis of particular proteins to the examination of various literary themes, the students whose scholarly endeavors are represented in this booklet pursued research projects that have explored new ideas; and their teachers have helped them to achieve their goals by providing expert guidance in the field of study, by challenging students to excel, and by encouraging them as they developed their ideas. Students and faculty should be very proud of the work reflected in these abstracts. These individual efforts and collaborations reveal what is best about Winthrop University as a learning community.

Copeptin Is Associated with Kidney Length, Renal Function, and Prevalence of Simple Cysts in a Population-Based Study.

Arginine vasopressin (AVP) has a key role in osmoregulation by facilitating water transport in the collecting duct. Recent evidence suggests that AVP may have additional effects on renal function and favor cyst growth in polycystic kidney disease. Whether AVP also affects kidney structure in the general population is unknown. We analyzed the association of copeptin, an established surrogate for AVP, with parameters of renal function and morphology in a multicentric population-based cohort. Participants from families of European ancestry were randomly selected in three Swiss cities. We used linear multilevel regression analysis to explore the association of copeptin with renal function parameters as well as kidney length and the presence of simple renal cysts assessed by ultrasound examination. Copeptin levels were log-transformed. The 529 women and 481 men had median copeptin levels of 3.0 and 5.2 pmol/L, respectively (P<0.001). In multivariable analyses, the copeptin level was associated inversely with eGFR (β=-2.1; 95% confidence interval [95% CI], -3.3 to -0.8; P=0.002) and kidney length (β=-1.2; 95% CI, -1.9 to -0.4; P=0.003) but positively with 24-hour urinary albumin excretion (β=0.11; 95% CI, 0.01 to 0.20; P=0.03) and urine osmolality (β=0.08; 95% CI, 0.05 to 0.10; P<0.001). A positive association was found between the copeptin level and the presence of renal cysts (odds ratio, 1.6; 95% CI, 1.1 to 2.4; P=0.02). These results suggest that AVP has a pleiotropic role in renal function and may favor the development of simple renal cysts.

Effect of the REG1 anticoagulation system versus bivalirudin on outcomes after percutaneous coronary intervention (REGULATE-PCI): a randomised clinical trial.

BACKGROUND REG1 is a novel anticoagulation system consisting of pegnivacogin, an RNA aptamer inhibitor of coagulation factor IXa, and anivamersen, a complementary sequence reversal oligonucleotide. We tested the hypothesis that near complete inhibition of factor IXa with pegnivacogin during percutaneous coronary intervention, followed by partial reversal with anivamersen, would reduce ischaemic events compared with bivalirudin, without increasing bleeding. METHODS We did a randomised, open-label, active-controlled, multicentre, superiority trial to compare REG1 with bivalirudin at 225 hospitals in North America and Europe. We planned to randomly allocate 13,200 patients undergoing percutaneous coronary intervention in a 1:1 ratio to either REG1 (pegnivacogin 1 mg/kg bolus [>99% factor IXa inhibition] followed by 80% reversal with anivamersen after percutaneous coronary intervention) or bivalirudin. Exclusion criteria included ST segment elevation myocardial infarction within 48 h. The primary efficacy endpoint was the composite of all-cause death, myocardial infarction, stroke, and unplanned target lesion revascularisation by day 3 after randomisation. The principal safety endpoint was major bleeding. Analysis was by intention to treat. This trial is registered at ClinicalTrials.gov, identifier NCT01848106. The trial was terminated early after enrolment of 3232 patients due to severe allergic reactions. FINDINGS 1616 patients were allocated REG1 and 1616 were assigned bivalirudin, of whom 1605 and 1601 patients, respectively, received the assigned treatment. Severe allergic reactions were reported in ten (1%) of 1605 patients receiving REG1 versus one (<1%) of 1601 patients treated with bivalirudin. The composite primary endpoint did not differ between groups, with 108 (7%) of 1616 patients assigned REG1 and 103 (6%) of 1616 allocated bivalirudin reporting a primary endpoint event (odds ratio [OR] 1·05, 95% CI 0·80-1·39; p=0·72). Major bleeding was similar between treatment groups (seven [<1%] of 1605 receiving REG1 vs two [<1%] of 1601 treated with bivalirudin; OR 3·49, 95% CI 0·73-16·82; p=0·10), but major or minor bleeding was increased with REG1 (104 [6%] vs 65 [4%]; 1·64, 1·19-2·25; p=0·002). INTERPRETATION The reversible factor IXa inhibitor REG1, as currently formulated, is associated with severe allergic reactions. Although statistical power was limited because of early termination, there was no evidence that REG1 reduced ischaemic events or bleeding compared with bivalirudin. FUNDING Regado Biosciences Inc.

Potemkin conservatism. An ideological tool of the Kremlin. OSW Point of View 48, February 2015

Since the beginning of his third presidential term, Vladimir Putin has consistently invoked conservative ideology. Thus he legitimises the Kremlin’s new political strategy, the aim of which is to stabilise the regime and prevent any political mobilisation in Russia around a liberal agenda. This strategy is also intended to strengthen the legitimacy of the current model of government, by portraying it as ‘traditional’ for Russia; and to justify the government’s repressive and anti-Western policies. It also includes the policy of reintegrating the post-Soviet space under the auspices of Moscow, as evidenced by the annexation of Crimea and the Novorossiya project. This strategy was devised as a response to the galvanisation of adherents of liberalisation in Russia, namely the new middle class and a part of the business and administrative elites who publicly demonstrated their dissatisfaction with the regime in 2011 and 2012. However, the dissonance between the conservative slogans mouthed by the ruling elite and its actual conduct suggest that the Kremlin’s ‘conservative project’ is purely instrumental in nature, which in the longer term will undercut its effectiveness by undermining its credibility in the eyes of Russian society.

The Southern Gas Corridor. The Azerbaijani-Turkish project becomes part of the game between Russia and the EU. OSW POINT OF VIEW 53, 2015-08-20

The Southern Gas Corridor is a system of three complementary gas pipeline projects controlled by Azerbaijan and Turkey, each at a different stage of implementation. The crisis in EU-Russia relations over Ukraine has made the two players interested in the Southern Gas Corridor once again. Brussels views it as an opportunity for a genuine diversification of gas supplies and a way to reinforce its position against Russia. In turn, Moscow’s proposal for Turkey and Greece to join the Turkish Stream gas pipeline project changes the energy map of the regional projects, which indirectly affects the Southern Gas Corridor. This has raised concern in Azerbaijan, which has been making efforts to manoeuvre between the interests of Moscow and Brussels.

The Aleut language, the elements of Aleut grammar with a dictionary in two parts containing basic vocabularies of Aleut and English,

"Aleut-English dictionary, compiled by Richard Henry Geoghegan. A vocabulary of the Aleutian or Unangan language as spoken on the eastern Aleutian Islands and on the Alaska Peninsula, being a translation of the Russian, 'Slovarʹ aleutsko-lisʹevskago yazyka' or 'Dictionary of the Aleut-Fox language', by Ivan Veniaminov, 1834, with additions and annotations by the compiler": p. 89-124.

Limits of allowable concentrations of atmospheric pollutants.

"Three reports issued by the U.S.S.R. Committee on the Determination of Limits of Allowable Concentrations of Atmospheric Pollutants. Published by the State Publishing House of Medical Literature, Medgiz of Moscow, 1952-1957."

The history of the Jews : from the earliest period down to modern times /

Original in the Princeton Theological Seminary.

Select treatises of S. Athanasius ... in controversy with the Arians /

Preface signed: J.H.N.

Auserlesene Gedichte von Julius Wilhelm Zinckgref, Andreas Tscherning, Ernst Christoph Homburg und Paul Gerhard.

"Über das Leben und die Schriften Julius Wilhelm Zinckgref's [etc.]": pp.[xi]-xxxviii.

Narratives of early Pennsylvania, West New Jersey and Delaware, 1630-1707,

--A further account of the province of Pennsylvania, by William Penn, 1685.--Letters of Doctor Nicholas More, and others, 1686.--A short description of Pennsylvania, by Richard Frame, 1692.--An historical and geographical account of Pennsylvania and West-New-Jersey, by Gabriel Thomas, 1698.--Circumstantial geographical description of Pennsylvania, by Francis Daniel Pastorius, 1700.--Letter of John Jones, 1725.